ChemicalBook >>Floxuridine>>Fluorodeoxyuridine(50-91-9)

Fluorodeoxyuridine(50-91-9)

Fluorodeoxyuridine(50-91-9)
Product IdentificationBack to Contents
【Product Name】

Fluorodeoxyuridine
【Synonyms】

1-(2-Deoxy-beta-D-ribofuranosyl)-5-fluorouracil
1-beta-D-2'-Deoxyribofuranosyl-5-flurouracil
2'-Deoxy-5-fluorouridine
Deoxyfluorouridine
FDUR
Floxuridin
【CAS】

50-91-9
【Formula】

C9H11FN2O5
【Molecular Weight】

246.2
【EINECS】

200-072-5
【RTECS】

YU7525000
【RTECS Class】

Drug; Mutagen; Reproductive Effector; Human Data
【Merck】

13,4138
【Beilstein/Gmelin】

90221
【Beilstein Reference】

5-24-06-00291
Physical and Chemical PropertiesBack to Contents
【Appearance】

Inhibits DNA synthesis.
【Solubility in water】

1 g in about 2 ml
【Melting Point】

153
【pKa/pKb】

7.44 (pKa)
【Partition Coefficient】

-1.16
【Usage】

Sustained release of large numbers of sterilized males of specific insect species has yielded remarkable control of certain insect pests of domestic animals & crop plants. Sterilization can be effected chemically, by feeding compd of known chemosterilant activity, such as fluorouracil deriv.
First Aid MeasuresBack to Contents
【Ingestion】

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
【Inhalation】

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】

Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Handling and StorageBack to Contents
【Storage】

Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.
【Handling】

Wash thoroughly after handling. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Hazards IdentificationBack to Contents
【Inhalation】

May cause respiratory tract irritation.
【Skin】

May cause skin irritation.
【Eyes】

May cause eye irritation.
【Ingestion】

Harmful if swallowed. Causes gastrointestinal irritation with nausea, vomiting and diarrhea. Stomatitis (inflamation of the mucous membranes in the mouth) is a common sign of toxicity.
【Hazards】

Contact with metals may evolve flammable hydrogen gas.
【EC Risk Phrase】

R 20/22 40 61
【EC Safety Phrase】

S 22 36/37/39 45
【UN (DOT)】

1760
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
【Exposure Effects】

Chronic ingestion may result in hair loss, nail changes, dermatitis and increased pigmentation of the skin.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water fog, dry chemical, carbon dioxide, or regular foam. Use agent most appropriate to extinguish fire.
【Fire Potential】

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability and ReactivityBack to Contents
【Stability】

Stable under normal temperatures and pressures.
【Incompatibilities】

Strong oxidizing agents, strong bases.
【Decomposition】

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrogen fluoride.
【Combustion Products】

Fire may produce irritating, corrosive and/or toxic gases.
Transport InformationBack to Contents
【UN Number】

1760
【Hazard Class】

8
【Packing Group】

I; II; III
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