ChemicalBook >>Propofol>>Propofol(2078-54-8)

Propofol(2078-54-8)

Propofol(2078-54-8)
Product IdentificationBack to Contents
【Product Name】

Propofol
【Synonyms】

2,6-Bis(1-methylethyl)phenol
2,6-Bis(isopropyl)phenol
2,6-Diisopropylphenol
Diprofol
Disoprivan
Recofol
【CAS】

2078-54-8
【Formula】

C12H18O
【Molecular Weight】

178.27
【EINECS】

218-206-6
【RTECS】

SL0810000
【RTECS Class】

Drug; Reproductive Effector; Human Data
【Merck】

12,8020
【Beilstein/Gmelin】

1866484
【Beilstein Reference】

4-06-00-03435
Physical and Chemical PropertiesBack to Contents
【Appearance】

Yellow-tan liquid.
【Solubility in water】

Insoluble
【Melting Point】

18
【Boiling Point】

256
【Vapor Pressure】

0.01 (25 C)
【Density】

1.032 g/cm3
【pKa/pKb】

11.00 (pKa)
【Partition Coefficient】

4.16
【Heat Of Vaporization】

51.3 kJ/mol
【Usage】

An intravenous sedative-hypnotic agent.
【Refractive Index】

1.5134 (20 C)
First Aid MeasuresBack to Contents
【Ingestion】

Get medical aid. Wash mouth out with water.
【Inhalation】

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Handling and StorageBack to Contents
【Storage】

Store in a cool, dry place. Store in a tightly closed container. Keep under an argon blanket. Refrigerator (approx 4 C).
【Handling】

Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Use only in a chemical fume hood.
Hazards IdentificationBack to Contents
【Ingestion】

Harmful if swallowed. May cause irritation of the digestive tract.
【Inhalation】

Dust is irritating to the respiratory tract. The toxicological properties of this substance have not been fully investigated.
【Skin】

Causes skin irritation.
【Eyes】

Causes eye irritation.
【EC Risk Phrase】

R 22 36/38
【EC Safety Phrase】

S 26 36/37/39
【UN (DOT)】

2810
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Fire Fighting MeasuresBack to Contents
【Flash Point】

107
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container.
Stability and ReactivityBack to Contents
【Incompatibilities】

Oxidizing agents, bases, acid chlorides, acid anhydrides.
【Stability】

Stable under normal temperatures and pressures.
【Decomposition】

Carbon monoxide, carbon dioxide.
Transport InformationBack to Contents
【UN Number】

2810
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