| Product Identification | Back to Contents | 【Product Name】
Propofol | 【Synonyms】
2,6-Bis(1-methylethyl)phenol
2,6-Bis(isopropyl)phenol
2,6-Diisopropylphenol
Diprofol
Disoprivan
Recofol | 【CAS】
2078-54-8 | 【Formula】
C12H18O | 【Molecular Weight】
178.27 | 【EINECS】
218-206-6 | 【RTECS】
SL0810000 | 【RTECS Class】
Drug; Reproductive Effector; Human Data | 【Merck】
12,8020 | 【Beilstein/Gmelin】
1866484 | 【Beilstein Reference】
4-06-00-03435 |
| Physical and Chemical Properties | Back to Contents | 【Appearance】
Yellow-tan liquid. | 【Solubility in water】
Insoluble | 【Melting Point】
18 | 【Boiling Point】
256 | 【Vapor Pressure】
0.01 (25 C) | 【Density】
1.032 g/cm3 | 【pKa/pKb】
11.00 (pKa) | 【Partition Coefficient】
4.16 | 【Heat Of Vaporization】
51.3 kJ/mol | 【Usage】
An intravenous sedative-hypnotic agent. | 【Refractive Index】
1.5134 (20 C) |
| First Aid Measures | Back to Contents | 【Ingestion】
Get medical aid. Wash mouth out with water. | 【Inhalation】
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. | 【Skin】
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. | 【Eyes】
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. |
| Handling and Storage | Back to Contents | 【Storage】
Store in a cool, dry place. Store in a tightly closed container. Keep under an argon blanket. Refrigerator (approx 4 C). | 【Handling】
Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Use only in a chemical fume hood. |
| Hazards Identification | Back to Contents | 【Ingestion】
Harmful if swallowed. May cause irritation of the digestive tract. | 【Inhalation】
Dust is irritating to the respiratory tract. The toxicological properties of this substance have not been fully investigated. | 【Skin】
Causes skin irritation. | 【Eyes】
Causes eye irritation. | 【EC Risk Phrase】
R 22 36/38 | 【EC Safety Phrase】
S 26 36/37/39 | 【UN (DOT)】
2810 |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. | 【Respirators】
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. |
| Fire Fighting Measures | Back to Contents | 【Flash Point】
107 | 【Fire Fighting】
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. |
| Stability and Reactivity | Back to Contents | 【Incompatibilities】
Oxidizing agents, bases, acid chlorides, acid anhydrides. | 【Stability】
Stable under normal temperatures and pressures. | 【Decomposition】
Carbon monoxide, carbon dioxide. |
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