Ketanserin(74050-98-9)

Contents

Product Identification	Back to Contents
【Product Name】 Ketanserin
【Synonyms】 2,4(1H,3H)-Quinazolinedione, 3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]- 3-[2-[4-(4-Fluorobenzoyl)piperidin-1-yl]ethyl]-1H-quinazoline-2,4-dione
【CAS】 74050-98-9
【Formula】 C22H22FN3O3
【Molecular Weight】 395.43
【EINECS】 277-680-2
【Merck】 12,5307

Physical and Chemical Properties	Back to Contents
【Appearance】 White to off-white solid.
【Solubility in water】 Insoluble
【Melting Point】 231
【Density】 1.28 g/cm3 (20 C)
【pKa/pKb】 6.26 (pKb)
【Partition Coefficient】 3.21
【Usage】 Classified as an antihypertensive, serotonin antagonist.

First Aid Measures	Back to Contents
【Ingestion】 Remove dentures and clear mouth. If person is conscious, rinse mouth with water. Call physician or poison control immediately.
【Inhalation】 Remove from exposure. If breathing is difficult, administer oxygen. If breathing stops, administer artificial respiration. Seek medical attention immediately.
【Skin】 Wash with soap and water for 15 minutes. Remove contaminated clothing and shoes. Seek medical attention immediately.
【Eyes】 Check for and remove contact lenses. Flush eyes with running water for at least 15 minutes separating eyelids. Seek medical attention immediately

Handling and Storage	Back to Contents
【Storage】 This product should be stored at room temperature. It should be kept in a tightly closed container.

Exposure Controls/Personal Protection	Back to Contents
【Personal Protection】 For spill clean up, wear suitable protective clothing, chemical resistant rubber gloves, rubber boots, and chemical safety goggles. Self contained breathing apparatus or NIOSH/MSHA approved respirator is required.
【Exposure Effects】 May be harmful if ingested, inhaled, or absorbed through the skin. Symptoms of overexposure can include: low blood pressure, light-headedness, sedation, tremor, convulsions or vomiting.

Fire Fighting Measures	Back to Contents
【Fire Fighting】 Extinguish with carbon dioxide, dry chemical powder, polymer foam, water spray. Use self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures	Back to Contents
【Small spills/leaks】 Wipe up spill and place in sealed container and hold for disposal. Avoid raising dust. Ventilate the area and wash spill site after material has been removed.

Stability and Reactivity	Back to Contents
【Incompatibilities】 Oxidizing agents.
【Stability】 Stable if stored as directed.
【Combustion Products】 Carbon monoxide, Carbon dioxide, Nitrogen oxides, Fluorine, Hydrogen fluoride.

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