ChemicalBook >>Capsaicin>>(E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide(404-86-4)

(E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide(404-86-4)

(E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide(404-86-4)
Product IdentificationBack to Contents
【Product Name】

(E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide
【Synonyms】

(E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
N-(4-Hydroxy-3-methoxy)benzyl-8-methylnon-trans-6-enamide
Styptysat
trans-8-Methyl-n-vanillyl-6-nonenamide
【CAS】

404-86-4
【Formula】

C18H27NO3
【Molecular Weight】

305.42
【EINECS】

206-969-8
【RTECS】

RA8530000
【RTECS Class】

Tumorigen; Mutagen; Natural Product
【Merck】

12,1811
【Beilstein/Gmelin】

2816484
【Beilstein Reference】

4-13-00-02588
Physical and Chemical PropertiesBack to Contents
【Appearance】

Monoclinic, rectangular plates, scales from petroleum ether.
【Solubility in water】

practically insoluble in cold water
【Melting Point】

66.1
【Boiling Point】

210-220 (0.01 torr):
【Partition Coefficient】

3.04
【Usage】

Flavoring agent in foods, additive to topical creams, used in pepper mace.
First Aid MeasuresBack to Contents
【Ingestion】

Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
【Inhalation】

If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
【Skin】

Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
【Eyes】

Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.
Handling and StorageBack to Contents
【Storage】

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
【Handling】

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Hazards IdentificationBack to Contents
【Inhalation】

Capsaicin vapors, especially from burning, may cause significant pulmonary irritation and prolonged cough. Pulmonary edema and bronchospasm may occur.
【Skin】

Irritation, erythema, and burning pain without vesiculation often occurs when applied topically to human skin.
【Ingestion】

Biting plants which contain capsaicin may cause acute stinging of the lips, tongue, and oral mucosa, which may lead to vomiting and diarrhea. Epithelial cell sloughing or mild mucosal bleeding may occur.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
【Respirators】

Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
【Exposure Effects】

stimulates pain fibers and release immunoreactive somatostatin.
【Poison Class】

2
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability and ReactivityBack to Contents
【Stability】

No data.
【Incompatibilities】

Strong oxidizing agents.
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