ChemicalBook >>Fluocinolone acetonide>>6a,9a-Fifluoro-16a,17a-isopropylidenedioxy-1,4-pregnadiene-3,20-dione(67-73-2)

6a,9a-Fifluoro-16a,17a-isopropylidenedioxy-1,4-pregnadiene-3,20-dione(67-73-2)

6a,9a-Fifluoro-16a,17a-isopropylidenedioxy-1,4-pregnadiene-3,20-dione(67-73-2)
Product IdentificationBack to Contents
【Product Name】

6a,9a-Fifluoro-16a,17a-isopropylidenedioxy-1,4-pregnadiene-3,20-dione
【Synonyms】

6a,9a-Difluoro-16a-hydroxyprednisolone 16,17-acetonide
6a-Fluorotriamcinolone acetonide
Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11,12-dihydroxy-16, 17-[(1-methylethylidene)bis(oxy)]-, (6.alpha.,11.beta., 16.alpha.)-
Sinalar
Synandone
【CAS】

67-73-2
【Formula】

C24H30F2O6
【Molecular Weight】

452.5
【EINECS】

200-668-5
【RTECS】

TU3830000
【RTECS Class】

Drug; Mutagen; Reproductive Effector
【Merck】

12,4185
【Beilstein/Gmelin】

1358395
【Beilstein Reference】

5-19-06-00571
Physical and Chemical PropertiesBack to Contents
【Solubility in water】

Insoluble
【Melting Point】

267 - 269
【Boiling Point】

579
【Vapor Pressure】

9E-16 (25 C)
【pKa/pKb】

12.55 (pKa)
【Heat Of Vaporization】

99.4 kJ/mol
【Usage】

A synthetic steroid used as an anti-inflammatory and anti-pruritic agent.
First Aid MeasuresBack to Contents
【Ingestion】

If swallowed, wash out mouth with water provided person is conscious. Call a physician.
【Inhalation】

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen
Handling and StorageBack to Contents
【Storage】

Keep tightly closed. Store in a cool dry place.
Hazards IdentificationBack to Contents
【Inhalation】

Material is irritating to mucous membranes and upper respiratory tract.
【Skin】

Causes irritation. Toxic if absorbed through the skin.
【Eyes】

Causes irritation.
【Ingestion】

Harmful/toxic if swallowed
【Hazards】

Emits toxic fumes under fire conditions.
【EC Risk Phrase】

20/21/22 36/37/38 40
【EC Safety Phrase】

22 26 36
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Evacuate area. Wear self-contained breathing apparatus, rubber boots, and heavy rubber gloves. Wear disposable coveralls and discard them after use.
【Exposure Effects】

Limited evidence of a carcinogenic effect Possible teratogen. Possible mutagen.
Fire Fighting MeasuresBack to Contents
【Flash Point】

304
【Fire Fighting】

Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. Water spray. Carbon dioxide, dry chemical powder, or appropriate foam.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete. Do not breathe dust. Do not get in eyes, on skin, on clothing. Avoid prolonged or repeated exposure.
Stability and ReactivityBack to Contents
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Carbon monoxide, Carbon dioxide, Hydrogen fluoride.
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