应用
Benzyl (R)-(-)-mandelate can be employed as reactant to synthesize: (S)-α-Hydroxy-N-(2-phenylethyl)benzenepropanamide (α-hydroxyamides) by enzyme catalyzed amidation reaction. Optically pure (R)- monomethyl esters of 3-[(tert-butyldimethylsilyl)oxy]pentanedioic acid, which is employed in the preparation of HMG-CoA reductase inhibitors. O-Ibuprofenylmandelic acid via acylation reaction with optically active ibuprofen and subsequent hydrogenation. Benzyl (R)-2-fluoro-2-phenylacetate via deoxyfluorination of alcohols using AlkylFluor.It can also be used to prepare HMG-CoA reductase inhibitors.
Sigma-Aldrich西格玛奥德里奇(上海)贸易有限公司
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