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Cell reports

Cell reports

IF:7.5 CiteScore:13.8 Articles:1305
Cell Reports publishes high-quality research across the life sciences and focuses on new biological insight as its primary criterion for publication. The journal offers three primary article types: Reports, which are shorter single-point articles, research articles, which are longer and provide deeper mechanistic insights, and resources, which highlight significant technical advances or major informational datasets that contribute to biological advances. Reviews covering recent literature in emerging and active fields are also accepted. The Cell Reports Portfolio includes gold open-access journals that cover life, medical, and physical sciences, and its mission is to make cutting-edge research and methodologies available to a wide readership. The journal's professional in-house editors work closely with authors, reviewers, and the scientific advisory board, which consists of current and future leaders in their respective fields. The advisory board guides the scope, content, and quality of the journal, but editorial decisions are independently made by the in-house scientific editors of Cell Reports.

DUSP14 suppresses ferroptosis and promotes tumor progression of triple-negative breast cancer

Published: 28 October 2025 DOI: 10.1016/j.celrep.2025.116365
Yueyue Cao, Yitian Zheng, Ruiqi Niu, Tingting Wang, Haiyang Yu, Yicheng Tong, Yi-Da Tang, Yueyin Pan

The m6A reader IGF2BP2 promotes homologous recombination-mediated DNA repair by eliminating DNA-RNA hybrids

Published: 28 October 2025 DOI: 10.1016/j.celrep.2025.116438
Yating Sun, Haojie Zhang, Shiwei Li, Jinzhi Zhang, Bin Lyu, Liping Kang, Xinkun Teng, Mingwei Yin, Weidong Peng, Jingjing Wang, Zhimin Chu, Chengying Cui, Dejie Kong, Mingqing Wu, Yongqiang Wang, Jiadong Wang, Yang Li

DEAD-box helicase DDX24 is essential for endothelial mitochondrial function to maintain the blood-brain barrier

Published: 28 October 2025 DOI: 10.1016/j.celrep.2025.116428
Shuai Li, Yuxuan Liu, Yingying Dong, Yujiao Gong, Simeng He, Jianyu Yuan, Shengfeng Deng, Qianqian Zhang, Lijie Wang, Fei Liu, Qiuyun Tu, Hong Shan, Huanhuan He

Structural basis of peptide recognition and modulation for neuropeptide FF receptors

Published: 23 September 2025 DOI: 10.1016/j.celrep.2025.116160
Xinzhu Li, Heng Zhang, Wen Hu, Kai Wu, Shuai Li, Sanshan Jin, Yuling Yin, Qingning Yuan, H Eric Xu, Benxun Pan, Yi Jiang

Disrupting mitochondrial dynamics attenuates ferroptosis and chemotoxicity via upregulating NRF2-mediated FSP1 expression

Published: 23 September 2025 DOI: 10.1016/j.celrep.2025.116234
Shuang Ma, Jianhua Qin, Yao Zhang, Jing Luan, Na Sun, Guoyuan Hou, Jiyuan He, Yang Xiao, Wei Zhang, Minghui Gao

FGF-induced phospholipase Cγ signaling regulates lacrimal gland branching by competing with PI3K in phosphoinositide metabolism

Published: 26 August 2025 DOI: 10.1016/j.celrep.2025.116046
Qian Wang, Chenqi Tao, Yihua Wu, Karen E Anderson, Neoklis Makrides, Abdul Hannan, John Peregrin, Chyuan-Sheng Lin, Zhipeng Ding, Wei Li, Phillip Hawkins, Len Stephens, Xin Zhang

The Nα-acetyl-L-lysine/Loxl2/H2O2 promotes intestinal tumor growth in Drosophila and cell proliferation in human colorectal cancer

Published: 26 August 2025 DOI: 10.1016/j.celrep.2025.116126
Lei Geng, Zhen Fan, Rongbing Chen, Kyu-Chan Cho, Yining Liu, Yu Cheng, Jingfeng Yang, Ying Zhang, Xuefei Wei, Liyuan Gong, Yingyu Tang, Zhan Xu, Wuren Huang, Shahzad Toufeeq, Zongzhao Zhai, Lei Pan, Jun Zhang, Bin Li, Brenda T Beerntsen, Ji-Hoon Lee, Youli Xiao, Younghwa Na, Won-Jae Lee, Erjun Ling

Mitochondrial thermal proteome profiling reveals aberrant activation of pyruvate dehydrogenase upon cuproptosis

Published: 22 July 2025 DOI: 10.1016/j.celrep.2025.115937
Zongyu Huang, Yanjun Liu, Ya Zeng, Jun Wang, Siyuan Sun, Chris Soon Heng Tan, Peng R Chen

Precise metabolic dependencies of cancer through deep learning and validations

Published: 22 July 2025 DOI: 10.1016/j.celrep.2025.115945
Tao Wu, Xiangyu Zhao, Yu Zhang, Die Qiu, Kaixuan Diao, Dongliang Xu, Weiliang Wang, Xiaopeng Xiong, Xinxiang Li, Xue-Song Liu

Coiled-coil-domain-mediated TRIM E3 protein condensation modulates enzymatic activity and functional specificity

Published: 24 June 2025 DOI: 10.1016/j.celrep.2025.115766
Qi Chen, Peiguo Yang

Lipid-coated nanoparticles enhance the delivery of bacterial virulence factors as a potent toxoid vaccine platform against bacterial infections.

Published: 24 June 2025 DOI: 10.1016/j.celrep.2025.115786
Deli Zhuge, Yingnan Xiao, Yunxuan Huang, Yutong Zhong, Xueying Sun, Jing Wu, Shuangshuang Liu, Hui Liang, Weian Mao, Yuan Yang, Yijing Lin, Haonan Wang, Xuewei Yang, Xufei Zhang, Wenjie Sun, Caixia Liu, Yingzheng Zhao, Mengchun Chen, Yijie Chen

ENPP1 governs the metabolic regulation of effector T cells in autoimmunity by detecting cytosolic mitochondrial DNA

Published: 24 June 2025 DOI: 10.1016/j.celrep.2025.115851
Huiyan Ji, Wanwan Jiang, Juan Zhang, Mengdi Liu, Danhua Su, Jiaxin Lei, Lingyi Li, Ming Zheng, Ting Liu, Zhichun Liu, Qinghua Cao, Lin Xu, Sidong Xiong, Zhenke Wen

PI3K/AKT signaling mediates stress-inducible amyloid formation through c-Myc

Published: 27 May 2025 DOI: 10.1016/j.celrep.2025.115617
Emma Lacroix, Evgenia A Momchilova, Sahil Chandhok, Mythili Padavu, Richard Zapf, Timothy E Audas

Synaptic vesicle fusion promotes phosphatidylinositol 4-phosphate synthesis for efficient synaptic transmission

Published: 27 May 2025 DOI: 10.1016/j.celrep.2025.115634
Tomofumi Yoshida, Hiroyuki Kawano, Jumpei Omi, Tetsuya Hori, Yutaka Kobayashi, Naoto Saitoh, Junken Aoki, Shigeo Takamori

BCG-trained macrophages couple LDLR upregulation to type I IFN responses and antiviral immunity

Published: 22 April 2025 DOI: 10.1016/j.celrep.2025.115493
Yangdian Lai, Xiaoxu Yang, Dong Wei, Xin Wang, Ruiming Sun, Yunfei Li, Ping Ji, Yujie Bao, Tiancheng Chu, Chenxing Zhang, Qiming Liang, Jie Xu, Xinxin Zhang, Yingying Chen, Ying Wang

Decoding the structural basis of ligand recognition and biased signaling in the motilin receptor

Published: 25 March 2025 DOI: 10.1016/j.celrep.2025.115329
Chongzhao You, Mengting Jiang, Tianyu Gao, Zining Zhu, Xinheng He, Youwei Xu, Yuan Gao, Yi Jiang, H Eric Xu

GPNMB and ATP6V1A interact to mediate microglia phagocytosis of multiple types of pathological particles

Published: 25 March 2025 DOI: 10.1016/j.celrep.2025.115343
Mei Liu, Jianping Zhu, Jiawei Zheng, Xuan Han, Lijuan Jiang, Xiangzhen Tong, Yue Ke, Zhipeng Guo, Weiyuan Huang, Jin Cong, Meiqiu Liu, Su-Yan Lin, Shuang Zhu, Li Mei, Xingmei Zhang, Wangming Zhang, Wen-Jun Xin, Zhenhai Zhang, Yanwu Guo, Rongqing Chen

Structural basis of CXCR4 assembly and regulation

Published: 25 February 2025 DOI: 10.1016/j.celrep.2025.115255
Aijun Liu, Yezhou Liu, Richard D Ye

Nuclear-localized HKDC1 promotes hepatocellular carcinoma through phosphorylating RBBP5 to upregulate H3K4me3.

Published: 25 February 2025 DOI: 10.1016/j.celrep.2025.115250
Ling Ye, Shengqi Shen, Qiankun Mao, Hui Lu, Haiying Liu, Pinggen Zhang, Zetan Jiang, Wenhao Ma, Yuchen Sun, Yiyang Chu, Zilong Zhou, Rui Liu, Jian Li, Shi-Ting Li, Ping Gao, Huafeng Zhang

Carbonic anhydrase 2 facilitates sorafenib resistance by counteracting MCT4-mediated intracellular pH dysregulation in HCC

Published: 24 December 2024 DOI: 10.1016/j.celrep.2024.114996
Hui Lu, Huiya Liu, Ronghui Yan, Wenhao Ma, Haiying Liu, Rui Liu, Yuchen Sun, Ling Ye, Ping Gao, Weidong Jia, Pinggen Zhang, Huafeng Zhang