1,2-Dichlorobenzene
Product identifier
- Product name: 1,2-Dichlorobenzene
- CBnumber: CB9406935
- CAS: 95-50-1
- EINECS Number: 202-425-9
- Synonyms: 1,2-dichlorobenzene,O-Dichlorobenzene
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
Substance
- Product name: 1,2-Dichlorobenzene
- Synonyms: 1,2-dichlorobenzene,O-Dichlorobenzene
- CAS: 95-50-1
- EC number: 202-425-9
- MF: C6H4Cl2
- MW: 147
Description of first aid measures
General adviceMost important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
Extinguishing media
Suitable extinguishing mediaSpecial hazards arising from the substance or mixture
Carbon oxides Hydrogen chloride gas Combustible.
Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating.
Development of hazardous combustion gases or vapours possible in the event of fire.
Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Further information
Remove container from danger zone and cool with water. Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
| HEALTH | 2 | Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine) | |
| FIRE | 2 | Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur and multiple finely divided suspended solids that do not require heating before ignition can occur. Flash point between 37.8 and 93.3 °C (100 and 200 °F). (e.g. diesel fuel, sulfur) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert. For personal protection see section 8.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent material (e.g. Chemizorb? ). Dispose of properly. Clean up affected area.
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Advice on safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Storage conditions
Tightly closed. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons.
Light sensitive.
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
control parameter
Hazard composition and occupational exposure limitsExposure controls
Personal protective equipmentUse equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
protective clothing
Recommended Filter type: Filter A (acc. to DIN 3181) for vapours of organic compounds
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Do not let product enter drains.
Information on basic physicochemical properties
- Appearancecolorless, to, light yellow liquid, clear
- Odourcharacteristic
- Odour ThresholdNo data available
- pHNo data available
- Melting point/freezing pointMelting point/range: -18 - -17 °C - lit.
- Initial boiling point and boiling range178 - 180 °C - lit.
- Flash point66,0 °C - closed cup
- Evaporation rateNo data available
- Flammability (solid, gas)No data available
- Upper/lower flammability or explosive limits Upper explosion limit: 9,2 %(V) Lower explosion limit: 2,2 %(V)
- Vapour pressure 2,1 hPa at 35,0 °C
- Vapour density 5.1 (vs air)
- Relative density1,306 g/cm3 at 25 °C - lit. No data available
- Water solubilityca.0,1558 g/l at 25 °C - partly soluble
- Partition coefficient: n-octanol/waterlog Pow: 3,43 at 25 °C - Bioaccumulation is not expected., (Lit.)
- Autoignition temperature648,0 °C
- Decomposition temperatureNo data available
- ViscosityViscosity, kinematic: No data available Viscosity, dynamic: ca.1,324 mPa.s at 25 °C
- Explosive propertiesNo data available
- Oxidizing propertiesNo data available
- Henry's Law Constant1.92 at 25 °C (gas stripping-GC, Shiu and Mackay, 1997)
- λmaxλ: 296 nm Amax: 1.00
λ: 300 nm Amax: 0.30
λ: 305 nm Amax: 0.20
λ: 335 nm Amax: 0.05
λ: 375-400 nm Amax: 0.01
Other safety information
Surface tension ca.36,61 mN/m
Reactivity
Forms explosive mixtures with air on intense heating.
A range from approx. 15 Kelvin below the flash point is to be rated as critical.
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions
Alkali metals Alkaline earth metals Aluminum
Light metals
Conditions to avoid
Strong heating.
Incompatible materials
Aluminum, rubber, various plastics
Hazardous decomposition products
In the event of fire: see section 5
Information on toxicological effects
Acute toxicityRemarks: (Regulation (EC) No 1272/2008, Annex VI) LC50 Inhalation - Rat - 4 h - 8,15 mg/l
Remarks: (IUCLID)
LD50 Dermal - Rabbit - > 10.000 mg/kg Remarks: (RTECS)
Result: Skin irritation - 24 h (OECD Test Guideline 404)
Result: No eye irritation (OECD Test Guideline 405)
Remarks: (Regulation (EC) No 1272/2008, Annex VI)
Test system: Escherichia coli/Salmonella typhimurium Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471
Result: negative
Test Type: Mutagenicity (mammal cell test): chromosome aberration. Test system: lymphocyte
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 473
Result: negative
Test Type: In vitro mammalian cell gene mutation test Test system: Chinese hamster ovary cells
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 476
Result: negative
Test Type: In vivo micronucleus test Species: Mouse
Cell type: Bone marrow
Application Route: Intraperitoneal injection Method: OECD Test Guideline 474
Result: negative
Toxicity
Remarks: (ECHA)
static test EC50 - Ceriodaphnia dubia (water flea) - 0,66 mg/l - 48 h (US-EPA)
(US-EPA)
Persistence and degradability
Biodegradability aerobic - Exposure time 28 d
Result: 0 % - Not readily biodegradable. (OECD Test Guideline 301C)
Bioaccumulative potential
Bioaccumulation Cyprinus carpio (Carp) - 56 d
- 0,01 mg/l(1,2-Dichlorobenzene)
Bioconcentration factor (BCF): 90 - 260 (OECD Test Guideline 305C)
Mobility in soil
No data available
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
Waste treatment methods
Product
See www.retrologistik.com for processes regarding the return of chemicals and
containers, or contact us there if you have further questions.
IncompatibilitiesFor o-DCB and m-DCB: acid fumes, chlorides, strong oxidizers; hot aluminum, or aluminum alloys. For p-DCB: Strong oxidizers; although, incompatibilities for this chemical may also include other materials listed for o-DCB.
Waste DisposalIncineration, preferably after mixing with another combustible fuel. Care must be exercised to assure complete combustion to prevent the formation of phosgene. An acid scrubber is necessary to remove the halo acids produced.
UN number
ADR/RID: 1591 IMDG: 1591 IATA: 1591
UN proper shipping name
| | ADR/RID: o-DICHLOROBENZENE IMDG: ortho-DICHLOROBENZENE | |
| IATA: o-Dichlorobenzene | ||
| 14.3 | Transport hazard class(es) ADR/RID: 6.1 IMDG: 6.1 | IATA: 6.1 |
| 14.4 | Packaging group ADR/RID: III IMDG: III | IATA: III |
| 14.5 | Environmental hazards ADR/RID: yes IMDG Marine pollutant: yes | IATA: no |
| 14.6 | Special precautions for user No data available | |
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous ChemicalsAbbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.