1,2-Dichloroethane
Product identifier
- Product name: 1,2-Dichloroethane
- CBnumber: CB7295478
- CAS: 107-06-2
- EINECS Number: 203-458-1
- Synonyms: DCE,EDC
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
Substance
- Product name: 1,2-Dichloroethane
- Synonyms: DCE,EDC
- CAS: 107-06-2
- EC number: 203-458-1
- MF: C2H4Cl2
- MW: 98.96
Description of first aid measures
General adviceMost important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
Extinguishing media
Suitable extinguishing mediaSpecial hazards arising from the substance or mixture
Carbon oxides Hydrogen chloride gas Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors. Risk of dust explosion.
Development of hazardous combustion gases or vapours possible in the event of fire. Forms explosive mixtures with air at ambient temperatures.
Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Further information
Remove container from danger zone and cool with water. Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
| HEALTH | 2 | Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine) | |
| FIRE | 3 | Liquids and solids (including finely divided suspended solids) that can be ignited under almost all ambient temperature conditions . Liquids having a flash point below 22.8 °C (73 °F) and having a boiling point at or above 37.8 °C (100 °F) or having a flash point between 22.8 and 37.8 °C (73 and 100 °F). (e.g. gasoline, acetone) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert. For personal protection see section 8.
Environmental precautions
Do not let product enter drains. Risk of explosion.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material (e.g.
Chemizorb?). Dispose of properly. Clean up affected area.
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Advice on safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Storage conditions
Keep container tightly closed in a dry and well-ventilated place. Keep away from heat and
sources of ignition. Keep locked up or in an area accessible only to qualified or authorized persons.
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
control parameter
Hazard composition and occupational exposure limitsExposure controls
Personal protective equipmentUse equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Full contact Material: Viton?
Minimum layer thickness: 0,7 mm Break through time: 480 min
Material tested:Vitoject? (KCL 890 / Aldrich Z677698, Size M)
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Splash contact Material: Chloroprene
Minimum layer thickness: 0,65 mm Break through time: 10 min
Material tested:KCL 720 Camapren?
Flame retardant antistatic protective clothing.
Recommended Filter type: Filter A (acc. to DIN 3181) for vapours of organic compounds
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Do not let product enter drains. Risk of explosion.
Information on basic physicochemical properties
- Appearancecolorless viscous liquid
- Odourof solvents
- Odour Threshold3 ppm
- pHNo data available
- Melting point/freezing pointMelting point/range: -35 °C - lit.
- Initial boiling point and boiling range83 °C - lit.
- Flash pointca.13 °C - closed cup - DIN 51755 Part 1
- Evaporation rate4,1
- Flammability (solid, gas)No data available
- Upper/lower flammability or explosive limits Upper explosion limit: 15,9 %(V) Lower explosion limit: 6 %(V)
- Vapour pressure 87 hPa at 20 °C 102 hPa at 25 °C
- Vapour density 4,1 at 20 °C
- Relative density1,256 g/mL at 25 °C - lit. No data available
- Water solubility7,9 g/l at 25 °C - OECD Test Guideline 105- soluble
- Partition coefficient: n-octanol/waterlog Pow: 1,45 at 20 °C - Bioaccumulation is not expected.
- Autoignition temperature440 °C at 1.013 hPa - DIN 51794
- Decomposition temperature300 °C -
- ViscosityViscosity, kinematic: No data available Viscosity, dynamic: 0,83 mPa.s at 20 °C
- Explosive propertiesNo data available
- Oxidizing propertiesNo data available
- Henry's Law Constant11.24 at 30 °C (headspace-GC, Sanz et al., 1997)
Other safety information
Surface tension 32,45 mN/m at 20 °C
Relative vapor density
4,1 at 20 °C
Reactivity
Vapors may form explosive mixture with air.
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions
Exothermic reaction with: Alkaline earth metals alkali amides
Nitric acid nitrogen oxides Oxidizing agents Chlorine
powdered magnesium Zinc
Risk of explosion with:
Alkali metals powdered aluminium Powdered metals Potassium
nitrogen dioxide
Conditions to avoid
Warming.
Incompatible materials
various plastics, Light metals, Iron
Hazardous decomposition products
In the event of fire: see section 5
Information on toxicological effects
Acute toxicityLC50 Inhalation - Rat - male and female - 4 h - 7,8 mg/l (OECD Test Guideline 403)
LD50 Dermal - Rabbit - male - 4.890 mg/kg (OECD Test Guideline 402)
(OECD Test Guideline 404)
(OECD Test Guideline 405)
Test system: S. typhimurium
Metabolic activation: with and without metabolic activation Result: positive
Remarks: (ECHA) Test Type: Ames test
Test system: Escherichia coli
Metabolic activation: without metabolic activation Method: OECD Test Guideline 471
Result: positive
Test Type: In vitro mammalian cell gene mutation test Test system: human lymphoblastoid cells
Metabolic activation: without metabolic activation Method: OECD Test Guideline 476
Result: positive
Test Type: In vitro mammalian cell gene mutation test Test system: human lymphoblastoid cells
Metabolic activation: without metabolic activation Result: positive
Remarks: (ECHA)
Test Type: Mutagenicity (mammal cell test): chromosome aberration. Test system: Chinese hamster lung cells
Metabolic activation: with and without metabolic activation Result: positive
Remarks: (ECHA)
Test Type: unscheduled DNA synthesis assay Test system: rat hepatocytes
Metabolic activation: without metabolic activation Method: OECD Test Guideline 482
Result: positive
Test Type: Micronucleus test Species: Mouse
Application Route: Intraperitoneal Method: OECD Test Guideline 474 Result: negative
Test Type: Mutagenicity (mammal cell test): micronucleus. Species: Mouse
Cell type: Red blood cells (erythrocytes) Application Route: Oral
Method: OECD Test Guideline 474 Result: negative
Test Type: sister chromatid exchange assay Species: Rat
Cell type: mammary gland Application Route: inhalation (vapor)
Result: negative Remarks: (ECHA)
Species: Drosophila melanogaster Cell type: sperm
Application Route: Inhalation Method: OECD Test Guideline 477 Result: positive
Test Type: Transgenic rodent somatic cell gene mutation assay Species: Mouse
Application Route: Intraperitoneal Result: negative
Remarks: (ECHA)
Toxicity
(OECD Test Guideline 203)
static test EC50 - Daphnia magna (Water flea) - 160 mg/l - 48 h Remarks: (in soft water)
(IUCLID)
(OECD Test Guideline 201)
Persistence and degradability
Biodegradability aerobic - Exposure time 20 d
Result: > 90 % - Inherently biodegradable. Remarks: (ECHA)
Bioaccumulative potential
Bioaccumulation Lepomis macrochirus - 14 d
at 16 °C - 0,957 mg/l(1,2-Dichloroethane)
Bioconcentration factor (BCF): 2
Mobility in soil
No data available
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
No data available
Waste treatment methods
Product
See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.
IncompatibilitiesMay form explosive mixture with air. Reacts violently with strong oxidizers and caustics; chemically active metals, such as magnesium or aluminum powder, sodium and potassium; alkali metals; alkali amides; liquid ammonia. Decomposes to vinyl chloride and HCl above 600℃. Attacks plastics, rubber, coatings. Attacks many metals in presence of water.
Waste DisposalIncineration, preferably after mixing with another combustible fuel. Care must be exercised to assure complete combustion to prevent the formation of phosgene. An acid scrubber is necessary to remove the halo acids produced
UN number
ADR/RID: 1184 IMDG: 1184 IATA: 1184
UN proper shipping name
| | ADR/RID: ETHYLENE DICHLORIDE IMDG: ETHYLENE DICHLORIDE | |
| IATA: Ethylene dichloride | ||
| 14.3 | Transport hazard class(es) ADR/RID: 3 (6.1) IMDG: 3 (6.1) | IATA: 3 (6.1) |
| 14.4 | Packaging group ADR/RID: II IMDG: II | IATA: II |
| 14.5 | Environmental hazards ADR/RID: no IMDG Marine pollutant: no | IATA: no |
| 14.6 | Special precautions for user No data available | |
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous ChemicalsAbbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
Other Information
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.