Chemical Safety Data Sheet MSDS / SDS
2-PROPYLZINC BROMIDE SOLUTION 0.5M IN T&
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: 2-PROPYLZINC BROMIDE SOLUTION 0.5M IN T&
- CBnumber: CB1972285
- CAS: 77047-87-1
- Synonyms: zinc,propane,bromide;isopropylzinc bromide
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P403+P235 Store in a well-ventilated place. Keep cool.
P402+P404 Store in a dry place. Store in a closed container.
P370+P378 In case of fire: Use … for extinction.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P231+P232 Handle under inert gas. Protect from moisture.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P405 Store locked up.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P223 Keep away from any possible contact with water, because of violent reaction and possible flash fire.
Hazard statements
H351 Suspected of causing cancer
H335 May cause respiratory irritation
H314 Causes severe skin burns and eye damage
H261 In contact with water releases flammable gas
H225 Highly Flammable liquid and vapour
H333 May be harmful if inhaled
H318 Causes serious eye damage
H302 Harmful if swallowed
Substance
- Product name: 2-PROPYLZINC BROMIDE SOLUTION 0.5M IN T&
- Synonyms: zinc,propane,bromide;isopropylzinc bromide
- CAS: 77047-87-1
- MF: C3H7BrZn
- MW: 188.37
General advice
First aiders need to protect themselves. Show this safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Call in physician.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Call a physician immediately.
In case of eye contact
After eye contact: rinse out with plenty of water. Immediately call in ophthalmologist. Remove contact lenses.
If swallowed
After swallowing: make victim drink water (two glasses at most), avoid vomiting (risk of perforation). Call a physician immediately. Do not attempt to neutralise.
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
Protection of first-aiders
For personal protection see section 8.
Notes to physician
No data available
Suitable extinguishing media
Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
Water Foam
Specific hazards during fire fighting
Combustible. Pay attention to flashback. Vapours are heavier than air and may spread along floors. May not get in touch with: Water Development of hazardous combustion gases or vapours possible in the event of fire. Forms explosive mixtures with air at ambient temper- atures.
Hazardous combustion products
Nature of decomposition products not known.
Specific extinguishing methods
Remove container from danger zone and cool with water. Suppress (knock down) gases/vapours/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
Special protective equipment for fire-fighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
NFPA 704
3
3
2
| HEALTH | 3 | Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid) | |
| FIRE | 3 | Liquids and solids (including finely divided suspended solids) that can be ignited under almost all ambient temperature conditions . Liquids having a flash point below 22.8 °C (73 °F) and having a boiling point at or above 37.8 °C (100 °F) or having a flash point between 22.8 and 37.8 °C (73 and 100 °F). (e.g. gasoline, acetone) | |
| REACT | 2 | Undergoes violent chemical change at elevated temperatures and pressures, reacts violently with water, or may form explosive mixtures with water (e.g. white phosphorus, potassium, sodium) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapours, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition. Evacuate the danger area, observe emergency procedures, consult an expert. Advice for emergency responders: For personal protection see section 8.
Environmental precautions
Do not let product enter drains. Risk of explosion.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material . Dispose of properly. Clean up affected area.
Handling
Advice on protection against fire and explosionKeep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against static discharge.
Advice on safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols. Keep workplace dry. Do not allow product to come into contact with water.
Avoidance of contact
Oxidizing agents Strong oxidizing agents Oxygen
Storage
Further information on storage conditionsTightly closed. Keep away from heat and sources of ignition.
Materials to avoid
Never allow product to get in contact with water during storage.
Storage class
4.3, Hazardous materials, which set free flammable gases upon contact with water
Recommended storage temperature
2 - 8 °C
Further information on storage stability
Air and moisture sensitive. Handle and store under inert gas. Refrigerate before opening. Test for peroxide formation periodically and before distillation. Dry residue is explosive. Test for peroxide formation periodically and before distillation.
Packaging material
Suitable material: Sure-Seal Bottles
Ingredients with workplace control parameters
Biological occupational exposure limits drofuran shift BEI (As soon as possible after exposure ceases)
Engineering measures
No data available
Personal protective equipment
Respiratory protectionrequired when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Filter type ABEK
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Eye/face protection
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Tightly fitting safety goggles
Skin and body protection
Tightly fitting safety goggles
Flame retardant antistatic protective clothing.
Hand protection
Material
butyl-rubber
Break through time
10 min
Glove thickness
0.3 mm
Protective index
Splash contact
Manufacturer
Butoject® (KCL 897 / Aldrich Z677647, Size M)
Manufacturer
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374
Remarks
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Hygiene measures
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
Information on basic physicochemical properties
- Relative density0.963 g/mL at 25 °C
- Relative vapor densityNo data available
- Vapor pressure191 hPa (20 °C)
- Lower explosion limit / Lower flammability limitLower flammability limit
- Upper explosion limit / Upper flammability limitUpper flammability limit
- Self-ignition215 °C 1,013 hPa
- Burning rateNo data available
- Flammability (liquids)No data available
- Flammability (solid, gas)No data available
- Evaporation rate> 1
- Flash point-20 °C
- Boiling point/boiling range65 - 67 °C (1,013 hPa)
- Particle characteristics Particle sizeNo data available
- Molecular weight188.38 g/mol
- Oxidizing propertiesnone
- Explosive propertiesNot classified as explosive.
- Flow timeNo data available
- Viscosity, kinematicNo data available
- Viscosity, dynamicNo data available
- Decomposition temperatureNo data available
- Autoignition temperature215 °C
- Partition coefficient: n-octanol/waterNo data available
- Water solubilityReacts with water.
- Density0.963 g/cm3 (25 °C)
- Melting point/ range-108 °C
- pHNo data available
- Odor ThresholdNo data available
- OdorNo data available
- ColorNo data available
- Appearanceliquid
Reactivity
Formation of peroxides possible. Vapours may form explosive mixture with air.
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions
No data available
Conditions to avoid
Warming. Moisture.
Incompatible materials
Oxidizing agents Strong oxidizing agents Oxygen
Hazardous decomposition products
Peroxides : In the event of fire: see section 5
11.1 Information on toxicological effects
Acute toxicityOral: No data available
Acute toxicity estimate Inhalation - 4 h - > 10 mg/l - dust/mist(Calculation meth- od)
Symptoms: mucosal irritations, Cough, Shortness of breath, Possible damages:, damage of respiratory tract
Acute toxicity estimate Dermal - > 5,000 mg/kg (Calculation method)
Skin corrosion/irritation
Acute toxicity estimate Inhalation - 4 h - > 10 mg/l - dust/mist(Calculation meth- od)
Symptoms: mucosal irritations, Cough, Shortness of breath, Possible damages:, damage of respiratory tract
Acute toxicity estimate Dermal - > 5,000 mg/kg (Calculation method)
Remarks: Mixture causes burns.
Serious eye damage/eye irritation
Remarks: Mixture causes serious eye damage.
Risk of blindness!
Respiratory or skin sensitization
Risk of blindness!
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Evidence of a carcinogenic effect.
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Mixture may cause respiratory irritation.
Mixture may cause drowsiness or dizziness.
Specific target organ toxicity - repeated exposure
Mixture may cause drowsiness or dizziness.
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
Central nervous system depression, Cough, chest pain, Difficulty in breathing, Ex- posure to high airborne concentrations can cause anesthetic effects., To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Other dangerous properties can not be excluded.
This substance should be handled with particular care.
Handle in accordance with good industrial hygiene and safety practice.
Other dangerous properties can not be excluded.
This substance should be handled with particular care.
Handle in accordance with good industrial hygiene and safety practice.
Ecotoxicity
Components:
Tetrahydrofuran:
Toxicity to fishLC50 (Pimephales promelas (fathead minnow)): 2,160 mg/l End point: mortality Exposure time: 96 h Test Type: flow-through test Analytical monitoring: yes Method: OECD Test Guideline 203
Toxicity to daphnia and other aquatic invertebrates
EC50 (Daphnia magna (Water flea)): 3,485 mg/l End point: mortality Exposure time: 48 h Test Type: static test Method: OECD Test Guideline 202
Toxicity to fish (Chronic toxicity)
NOEC (Pimephales promelas (fathead minnow)): 216 mg/l End point: Growth inhibition Exposure time: 33 d Test Type: flow-through test Analytical monitoring: yes Remarks: (ECHA)
Persistence and degradability
Components:
Tetrahydrofuran:
Biodegradabilityaerobic Inoculum: activated sludge Concentration: 2 mg/l Biochemical oxygen demand Result: Not readily biodegradable. Biodegradation: 39 % Exposure time: 28 d Method: OECD Test Guideline 301D
Bioaccumulative potential
Components:
Tetrahydrofuran:
Partition coefficient: noctanol/waterlog Pow: 0.45 (25 °C) Method: OECD Test Guideline 107 Remarks: Bioaccumulation is not expected.
Mobility in soil
No data available
Other adverse effects
Components:
Tetrahydrofuran:
Results of PBT and vPvB assessmentSubstance does not meet the criteria for PBT or vPvB according to Regulation (EC) No 1907/2006, Annex XIII.
Disposal methods
Waste from residuesOffer surplus and non-recyclable solutions to a licensed disposal company.
International Regulations
IATA-DGR
UN/ID No. : UN 3399
Proper shipping name : Organometallic substance, liquid, water-reactive, flammable (Propylzinc bromide, Tetrahydrofuran)
Class : 4.3
Subsidiary risk : 3
Packing group : II
Labels : Division 4.3 - Substances which in contact with water emit flammable gases, Class 3 - Flammable liquids
Packing instruction (cargo aircraft) : 494
Packing instruction (passenger aircraft) : 493
Proper shipping name : Organometallic substance, liquid, water-reactive, flammable (Propylzinc bromide, Tetrahydrofuran)
Class : 4.3
Subsidiary risk : 3
Packing group : II
Labels : Division 4.3 - Substances which in contact with water emit flammable gases, Class 3 - Flammable liquids
Packing instruction (cargo aircraft) : 494
Packing instruction (passenger aircraft) : 493
IMDG-Code
UN number : UN 3399
Proper shipping name : ORGANOMETALLIC SUBSTANCE, LIQUID, WATERREACTIVE, FLAMMABLE (Propylzinc bromide, Tetrahydrofuran)
Class : 4.3
Subsidiary risk : 3
Packing group : II
Labels : 4.3 (3)
EmS Code : F-G, S-N
Marine pollutant : no
Proper shipping name : ORGANOMETALLIC SUBSTANCE, LIQUID, WATERREACTIVE, FLAMMABLE (Propylzinc bromide, Tetrahydrofuran)
Class : 4.3
Subsidiary risk : 3
Packing group : II
Labels : 4.3 (3)
EmS Code : F-G, S-N
Marine pollutant : no
Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Not applicable for product as supplied.
National Regulations
JT/T 617
UN number : UN 3399
Proper shipping name : ORGANOMETALLIC SUBSTANCE, LIQUID, WATERREACTIVE, FLAMMABLE (Propylzinc bromide, Tetrahydrofuran)
Class : 4.3
Subsidiary risk : 3
Packing group : II
Labels : 4.3 (3)
Environmentally hazardous : no
Proper shipping name : ORGANOMETALLIC SUBSTANCE, LIQUID, WATERREACTIVE, FLAMMABLE (Propylzinc bromide, Tetrahydrofuran)
Class : 4.3
Subsidiary risk : 3
Packing group : II
Labels : 4.3 (3)
Environmentally hazardous : no
Special precautions for user
The transport classification(s) provided herein are for informational purposes only, and solely based upon the properties of the unpackaged material as it is described within this Safety Data Sheet. Transportation classifications may vary by mode of transportation, package sizes, and variations in regional or country regulations.
Downstream users need to comply with the conditions of safe use of the chemical, understand the environmental and health hazard and risk management measures identified on the SDS as well as the local/national regulations concerning the chemical.
National regulatory information
Law on the Prevention and Control of Occupational Diseases
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals
Listed
Identification of Major Hazard Installations for Hazardous Chemicals (GB 18218)
No. / Code Chemical name / Category Threshold quantity
W5.3 Flammable liquids 1,000 t
Hazardous Chemicals for Priority Management
Not listed under SAWS
Regulations on Labour Protection in Workplaces where Toxic Substances are Used
Catalogue of Highly Toxic Chemicals
Not listed
Regulation of Environmental Management on the First Import of Chemicals and the Import and Export of Toxic Chemicals
China Severely Restricted Toxic Chemicals for Import and Export
Not listed
Measures on the Environmental Administration of New Chemical Substances Registration
Registration/Notification number
B1A222241373
Full text of other abbreviations
ACGIHUSA. ACGIH Threshold Limit Values (TLV)
ACGIH BEI
ACGIH - Biological Exposure Indices (BEI)
GBZ 2.1-2007
Occupational exposure limits for hazardous agents in the workplace - Chemical hazardous agents.
ACGIH / TWA
8-hour, time-weighted average
ACGIH / STEL
Short-term exposure limit
GBZ 2.1-2007 / PC-TWA AIIC - Australian Invent Transport by Land of Bra bw - Body weight; CMR Standard of the German List (Canada); ECx - Conc associated with x% respo Chemical Substances (Jap response; ERG - Emerge GLP - Good Laboratory P cer; IATA - International Construction and Equipm Half maximal inhibitory c tion; IECSC - Inventory o tional Maritime Dangerou Industrial Safety and H Standardisation; KECI - K tration to 50 % of a test (Median Lethal Dose); MA lution from Ships; MERC of Dangerous Goods; n.o. - No Observed (Adverse) fect Level; NOELR - No Norm; NTP - National Toxi icals; OECD - Organisatio fice of Chemical Safety a and Toxic substance; PIC stances; (Q)SAR - (Quant (EC) No 1907/2006 of th Registration, Evaluation, Accelerating Decompositi Chemical Substance Inve Thailand Existing Chemica States); UN - United Nat Transport of Dangerous WHMIS - Workplace Hazar
Permissible concentration - time weighted average ry of Industrial Chemicals
ANTT - National Agency for il
ASTM - American Society for the Testing of Materials
- Carcinogen, Mutagen or Reproductive Toxicant
DIN nstitute for Standardisation
DSL - Domestic Substances ntration associated with x% response
ELx - Loading rate se
EmS - Emergency Schedule
ENCS - Existing and New n)
ErCx - Concentration associated with x% growth rate cy Response Guide
GHS - Globally Harmonised System
actice
IARC - International Agency for Research on Canir Transport Association
IBC - International Code for the nt of Ships carrying Dangerous Chemicals in Bulk
IC50 ncentration
ICAO - International Civil Aviation Organiza- Existing Chemical Substances in China
IMDG - Interna- Goods
IMO - International Maritime Organisation
ISHL alth Law (Japan)
ISO - International Organisation for rea Existing Chemicals Inventory
LC50 - Lethal Concenopulation
LD50 - Lethal Dose to 50% of a test population POL - International Convention for the Prevention of Pol- SUR - The Agreement for the Facilitation of the Transport . - Not Otherwise Specified
Nch - Chilean Norm
NO(A)EC ffect Concentration
NO(A)EL - No Observed (Adverse) Efbservable Effect Loading Rate
NOM - Official Mexican ology Program
NZIoC - New Zealand Inventory of Chemfor Economic Co-operation and Development
OPPTS - Ofd Pollution Prevention
PBT - Persistent, Bioaccumulative S - Philippines Inventory of Chemicals and Chemical Subtative) Structure Activity Relationship
REACH - Regulation European Parliament and of the Council concerning the uthorisation and Restriction of Chemicals
SADT - Selfn Temperature
SDS - Safety Data Sheet
TCSI - Taiwan tory
TDG - Transportation of Dangerous Goods
TECI s Inventory
TSCA - Toxic Substances Control Act (United ons
UNRTDG - United Nations Recommendations on the oods
vPvB - Very Persistent and Very Bioaccumulative
ous Materials Information System
ANTT - National Agency for il
ASTM - American Society for the Testing of Materials
- Carcinogen, Mutagen or Reproductive Toxicant
DIN nstitute for Standardisation
DSL - Domestic Substances ntration associated with x% response
ELx - Loading rate se
EmS - Emergency Schedule
ENCS - Existing and New n)
ErCx - Concentration associated with x% growth rate cy Response Guide
GHS - Globally Harmonised System
actice
IARC - International Agency for Research on Canir Transport Association
IBC - International Code for the nt of Ships carrying Dangerous Chemicals in Bulk
IC50 ncentration
ICAO - International Civil Aviation Organiza- Existing Chemical Substances in China
IMDG - Interna- Goods
IMO - International Maritime Organisation
ISHL alth Law (Japan)
ISO - International Organisation for rea Existing Chemicals Inventory
LC50 - Lethal Concenopulation
LD50 - Lethal Dose to 50% of a test population POL - International Convention for the Prevention of Pol- SUR - The Agreement for the Facilitation of the Transport . - Not Otherwise Specified
Nch - Chilean Norm
NO(A)EC ffect Concentration
NO(A)EL - No Observed (Adverse) Efbservable Effect Loading Rate
NOM - Official Mexican ology Program
NZIoC - New Zealand Inventory of Chemfor Economic Co-operation and Development
OPPTS - Ofd Pollution Prevention
PBT - Persistent, Bioaccumulative S - Philippines Inventory of Chemicals and Chemical Subtative) Structure Activity Relationship
REACH - Regulation European Parliament and of the Council concerning the uthorisation and Restriction of Chemicals
SADT - Selfn Temperature
SDS - Safety Data Sheet
TCSI - Taiwan tory
TDG - Transportation of Dangerous Goods
TECI s Inventory
TSCA - Toxic Substances Control Act (United ons
UNRTDG - United Nations Recommendations on the oods
vPvB - Very Persistent and Very Bioaccumulative
ous Materials Information System
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.
Recommended Products
TERT-BUTYLZINC BROMIDE SDS
1-METHYLBUTYLZINC BROMIDE SDS
2-PROPYLZINC BROMIDE SOLUTION 0.5M IN T& SDS
A-METHYLBENZYLZINC BROMIDE SDS
EXO-2-NORBORNYLZINC BROMIDE SDS
2-BUTYLZINC BROMIDE SDS
CYCLOPROPYLZINC BROMIDE SOLUTION 0.5M I& SDS
CYCLOPENTYLZINC BROMIDE SDS
1-ETHYLPROPYLZINC BROMIDE SDS
2-ADAMANTYLZINC BROMIDE SDS