Chemical Safety Data Sheet MSDS / SDS

TERT-BUTYL 4-(2-HYDROXYETHYL)PIPERAZINE-1-CARBOXYLATE

Revision Date:2026-03-21Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

Product name: TERT-BUTYL 4-(2-HYDROXYETHYL)PIPERAZINE-1-CARBOXYLATE
CBnumber: CB8389646
CAS: 77279-24-4
Synonyms: 1-BOC-4-(2-HYDROXYETHYL)-PIPERAZINE

Relevant identified uses of the substance or mixture and uses advised against

Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
Uses advised against: none

Company Identification

Company: Chemicalbook
Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

Symbol(GHS)

Signal wordDanger

Precautionary statements

P273 Avoid release to the environment.

Hazard statements

H400 Very toxic to aquatic life

H301 Toxic if swalloed

SECTION 3: Composition/information on ingredients

Substance

Product name: TERT-BUTYL 4-(2-HYDROXYETHYL)PIPERAZINE-1-CARBOXYLATE
Synonyms: 1-BOC-4-(2-HYDROXYETHYL)-PIPERAZINE
CAS: 77279-24-4
MF: C11H22N2O3
MW: 230.3

SECTION 4: First aid measures

4.1 Description of first-aid measures

General advice

Consult a physician. Show this material safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration.
Consult a physician.

In case of skin contact

Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.

In case of eye contact

Flush eyes with water as a precaution.

If swallowed

Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

4.2 Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11

4.3 Indication of any immediate medical attention and special treatment needed

No data available

4.4 Notes to physician

No data available

SECTION 5: Firefighting measures

5.1 Extinguishing media

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

5.2 Special hazards arising from the substance or mixture

Carbon oxides
Nitrogen oxides (NOx)
Combustible.

5.3 Advice for firefighters

Wear self-contained breathing apparatus for firefighting if necessary.

NFPA 704

HEALTH	3	Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid)
FIRE	0	Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Materials that will not burn in air when exposed to a temperature of 820 °C (1,500 °F) for a period of 5 minutes.(e.g. Carbon tetrachloride)
REACT	0	Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)
SPEC. HAZ.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Wear respiratory protection. Avoid dust formation. Avoid breathing vapors, mist or gas.
Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
For personal protection see section 8.

6.2 Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
Discharge into the environment must be avoided.

6.3 Methods and materials for containment and cleaning up

Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.

6.4 Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

7.1 Precautions for safe handling

Advice on safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols.

Advice on protection against fire and explosion

Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire protection.

Hygiene measures

Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product.
For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Storage conditions

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Storage class

Storage class (TRGS 510): 6.1D: Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

SECTION 8: Exposure controls/personal protection

8.1 Control parameters

Ingredients with workplace control parameters

We are not aware of any national exposure limit.

8.2 Exposure controls

Appropriate engineering controls

Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product.

Personal protective equipment

Eye/face protection

Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.

Body Protection

Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection

Where risk assessment shows air-purifying respirators are appropriate use a full- face particle respirator type N99 (US) or type P2 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Control of environmental exposure

Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
Discharge into the environment must be avoided.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

a) Physical statesolid
b) ColorWhite to pale brown
c) OdorNo data available
d) Melting point/freezing pointMelting point/ range: 38 - 42 °C
e) Initial boiling point and boiling range114°C 0,1mm
f) Flammability (solid, gas)No data available
g) Upper/lower flammability or explosive limitsNo data available
h) Flash point> 110 °C - closed cup
i) Autoignition temperatureNo data available
j) Decomposition temperatureNo data available
k) pHNo data available
l) ViscosityViscosity, kinematic: No data available
Viscosity, dynamic: No data available
m) Water solubilityNo data available
n) Partition coefficient n-octanol/waterlog Pow: 0.581
o) Vapor pressureNo data available
p) Density1.092±0.06 g/cm3(Predicted)
Relative density1.092±0.06 g/cm3(Predicted)
q) Relative vapor densityNo data available
r) Particle characteristicsNo data available
s) Explosive propertiesNo data available
t) Oxidizing propertiesNo data available

9.2 Other safety information

No data available

SECTION 10: Stability and reactivity

10.1 Chemical stability

Stable under recommended storage conditions.

10.2 Possibility of hazardous reactions

No data available

10.3 Conditions to avoid

No data available

10.4 Incompatible materials

Strong oxidizing agents

10.5 Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects

Acute toxicity

Acute toxicity estimate Oral - 100 mg/kg (Calculation method)
Oral: No data available
LD50 Oral - 100 mg/kg
Inhalation: No data available
Dermal: No data available

Skin corrosion/irritation

Remarks: No data available

Serious eye damage/eye irritation

Remarks: No data available

Respiratory or skin sensitization