Chemical Safety Data Sheet MSDS / SDS

Hydrochloric acid

Revision Date:2026-04-04Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: Hydrochloric acid
  • CBnumber: CB7421538
  • CAS: 7647-01-0
  • EINECS Number: 231-595-7
  • Synonyms: HCl,Hydrochloric Acid

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Symbol(GHS)
  • Signal wordWarning
Precautionary statements
P390 Absorb spillage to prevent material damage.
P234 Keep only in original container.
Hazard statements
H290 May be corrosive to metals

SECTION 3: Composition/information on ingredients

Substance

  • Product name: Hydrochloric acid
  • Synonyms: HCl,Hydrochloric Acid
  • CAS: 7647-01-0
  • EC number: 231-595-7
  • MF: ClH
  • MW: 36.46

SECTION 4: First aid measures

General advice

First aiders need to protect themselves. Show this material safety data sheet to the doctor in attendance.

If inhaled

After inhalation: fresh air. Call in physician.

In case of skin contact

In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Call a physician immediately.

In case of eye contact

After eye contact: rinse out with plenty of water. Immediately call in ophthalmologist. Remove contact lenses.

If swallowed

After swallowing: make victim drink water (two glasses at most), avoid vomiting (risk of perforation). Call a physician immediately. Do not attempt to neutralise.

Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11

Protection of first-aiders

For personal protection see section 8.

Notes to physician

No data available

SECTION 5: Firefighting measures

Suitable extinguishing media

Water Foam Carbon dioxide (CO2) Dry powder

Unsuitable extinguishing media

For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards during fire fighting

Combustible. Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air at elevated temperatures. Development of hazardous combustion gases or vapours possible in the event of fire.

Hazardous combustion products

Carbon oxides Hydrogen chloride gas

Specific extinguishing methods

Remove container from danger zone and cool with water. Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.

Special protective equipment for fire-fighters

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

NFPA 704

3
0
1
HEALTH 3 Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid)
FIRE 0 Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Materials that will not burn in air when exposed to a temperature of 820 °C (1,500 °F) for a period of 5 minutes.(e.g. Carbon tetrachloride)
REACT 1 Normally stable, but can become unstable at elevated temperatures and pressures (e.g. propene)
SPEC. HAZ.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition. Evacuate the danger area, observe emergency procedures, consult an expert. Advice for emergency responders: For personal protection see section 8.

Environmental precautions

Do not let product enter drains. Risk of explosion.

Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent material (e.g. Chemizorb® ). Dispose of properly. Clean up affected area.

SECTION 7: Handling and storage

Handling

Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against static discharge.
Avoidance of contact
Oxidizing agents Soluble carbonates and phosphates Hydroxides Metals Peroxides permanganates, for example potassium permanganate Amines Alcohols Bases Alkali metals Fluorine hexalithium disilicide Metals

Storage

Conditions for safe storage
No metal containers.
Further information on storage conditions
Keep container tightly closed in a dry and wellventilated place. Keep away from heat and sources of ignition.
Storage class
3, Flammable liquids
Recommended storage temperature
Recommended storage temperature see product label.
Further information on
hygroscopic storage stability
Packaging material
Suitable material: Poly Drum

SECTION 8: Exposure controls/personal protection

control parameter

Hazard composition and occupational exposure limits
Does not contain substances with occupational exposure limits.

Engineering measures

No data available

Personal protective equipment

Respiratory protection
required when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type
Filter type ABEK
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Tightly fitting safety goggles
Skin and body protection
Flame retardant antistatic protective clothing.
Hand protection
Material
butyl-rubber
Break through time
480 min
Glove thickness
0.3 mm
Protective index
Full contact
Manufacturer
Butoject® (KCL 897 / Aldrich Z677647, Size M)
Material
Nitrile rubber
Break through time
30 min
Glove thickness
0.11 mm
Protective index
Splash contact
Manufacturer
(KCL 740 / Aldrich Z677272, Size M)
Manufacturer
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374
Remarks
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the EC approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • SolubilityH2O: soluble
  • Physical stateliquid
  • Viscosity1.7mm2/s
  • Dielectric constant4.6(20℃)
  • Particle characteristics Particle sizeNo data available
  • Molecular weight36.46 g/mol
  • Oxidizing propertiesnone
  • Explosive propertiesNot classified as explosive.
  • Flow timeNo data available
  • Viscosity, kinematicNo data available
  • Viscosity, dynamicNo data available
  • Decomposition temperatureNo data available
  • Autoignition temperatureNo data available
  • Partition coefficient: n-octanol/waterNo data available
  • Water solubilitymiscible
  • Density1.092 g/mL (25 °C)
  • Relative density1.2 g/mL at 25 °C (lit.)
  • Relative vapor density1.3 (vs air)
  • Vapor pressure613 psi ( 21.1 °C)
  • Lower explosion limit / Lower flammability limit2-13.4% (v/v) 2-Propanol)
  • Upper explosion limit / Upper flammability limit2-13.4% (v/v) 2-Propanol)
  • Burning rateNo data available
  • Flammability (liquids)No data available
  • Flammability (solid, gas)No data available
  • Evaporation rateNo data available
  • Flash point40 °C
  • Boiling point/boiling range>100 °C (lit.)
  • Melting point/ rangeNo data available
  • pH3.01(1 mM solution);2.04(10 mM solution);1.08(100 mM solution);
  • Odor ThresholdNo data available
  • OdorSharp, irritating odor detectable at 0.25 to 10 ppm
  • ColorLight Yellow
  • Appearanceliquid

SECTION 10: Stability and reactivity

Reactivity

Vapor/air-mixtures are explosive at intense warming.

Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .

Possibility of hazardous reactions

No data available

Conditions to avoid

Heating.

Incompatible materials

Oxidizing agents Soluble carbonates and phosphates Hydroxides Metals Peroxides permanganates, for example potassium permanganate Amines Alcohols Bases Alkali metals Fluorine hexalithium disilicide Metals

Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects

Mixture Acute toxicity
Oral: No data available
Acute toxicity estimate Oral - 3,425 mg/kg (Calculation method)
Symptoms: If ingested, severe burns of the mouth and throat, as well as a danger of perforation of the esophagus and the stomach.
Symptoms: mucosal irritations, Cough, Shortness of breath, Possible damages:, damage of respiratory tract
Dermal: No data available
Skin corrosion/irritation
Remarks: Causes burns.
Serious eye damage/eye irritation
Remarks: Risk of serious damage to eyes.
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2

11.2 Additional Information

Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., spasm, inflammation and edema of the larynx, spasm, inflammation and edema of the bronchi, pneumonitis, pulmonary edema, burning sensation, Cough, wheezing, laryngitis, Shortness of breath, Headache,
Nausea, Vomiting, Ingestion or inhalation of concentrated acetic acid causes dam- age to tissues of the respiratory and digestive tracts. Symptoms include: hema- temesis, bloody diarrhea, edema and/or perforation of the esophagus and pylorus, pancreatitis, hematuria, anuria, uremia, albuminuria, hemolysis, convulsions, bron- chitis, pulmonary edema, pneumonia, cardiovascular collapse, shock, and death.
Direct contact or exposure to high concentrations of vapor with skin or eyes can cause: erythema, blisters, tissue destruction with slow healing, skin blackening, hyperkeratosis, fissures, corneal erosion, opacification, iritis, conjunctivitis, and possible blindness., To the best of our knowledge, the chemical, physical, and toxi- cological properties have not been thoroughly investigated.
Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice.
Components acetic acid
Acute toxicity
LD50 Oral - Rat - 3,310 mg/kg
Remarks: (RTECS)
LC50 Inhalation - Mouse - 4 h - 2,819 mg/l - vapor
Remarks: (RTECS)
Dermal: No data available
Skin corrosion/irritation
Skin - Rabbit
Result: Causes burns. - 4 h (OECD Test Guideline 404)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Causes burns. - 4 h (OECD Test Guideline 405)
Remarks: (IUCLID)
Remarks: Causes serious eye damage.
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Test Type: Ames test
Test system: Salmonella typhimurium
Result: negative
Test Type: Mutagenicity (mammal cell test): chromosome aberration.
Test system: Chinese hamster ovary cells
Result: negative
Method: Mutagenicity (micronucleus test)
Species: Rat - male and female - Bone marrow
Result: negative
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
Hydrochloric Acid Acute toxicity
Symptoms: If ingested, severe burns of the mouth and throat, as well as a danger of perforation of the esophagus and the stomach.
Inhalation: Cough Difficulty in breathing
Symptoms: mucosal irritations, Cough, Shortness of breath, Inhalation may lead to the formation of oedemas in the respiratory tract., Possible damag- es:, damage of respiratory tract, tissue damage
Dermal: No data available
Skin corrosion/irritation
Skin - reconstructed human epidermis (RhE)
Result: Corrosive (OECD Test Guideline 431)
Serious eye damage/eye irritation
Eyes - Bovine cornea
Result: Causes serious eye damage. - 10 min (OECD Test Guideline 437)
Respiratory or skin sensitization
Maximization Test - Guinea pig
Result: negative (OECD Test Guideline 406)
Germ cell mutagenicity
Test Type: Chromosome aberration test in vitro
Test system: Chinese hamster ovary cells
Result: Positive results were obtained in some in vitro tests.
Remarks: (ECHA)
Test Type: mitotic recombination assay
Test system: Saccharomyces cerevisiae
Result: negative
Remarks: (ECHA)
Test Type: Ames test
Test system: mouse lymphoma cells
Result: positive
Remarks: (ECHA)
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
May cause respiratory irritation. - Respiratory system
Acute oral toxicity - If ingested, severe burns of the mouth and throat, as well as a danger of perforation of the esophagus and the stomach.
Acute inhalation toxicity - mucosal irritations, Cough, Shortness of breath,
Inhalation may lead to the formation of oedemas in the respiratory tract.,
Possible damages:, damage of respiratory tract, tissue damage
Specific target organ toxicity - repeated exposure
The substance or mixture is not classified as specific target organ toxicant, repeated exposure.
Aspiration hazard
No aspiration toxicity classification

SECTION 12: Ecological information

Ecotoxicity

Toxicity to fish
Remarks: No data available

Components:

acetic acid:

Toxicity to fish
LC50 (Oncorhynchus mykiss (rainbow trout)): > 1,000 mg/l End point: mortality Exposure time: 96 h Test Type: semi-static test Method: OECD Test Guideline 203 GLP: yes
Toxicity to daphnia and other aquatic invertebrates
EC50 (Daphnia magna (Water flea)): > 1,000 mg/l End point: Immobilization Exposure time: 48 h Test Type: static test Analytical monitoring: yes Method: OECD Test Guideline 202 GLP: yes
Toxicity to algae/aquatic plants
EC50 (Skeletonema costatum): > 1,000 mg/l Exposure time: 72 h Test Type: static test Method: ISO 10253 GLP: yes
Toxicity to microorganisms
EC5 (Pseudomonas putida): 2,850 mg/l Exposure time: 16 h Remarks: neutral (maximum permissible toxic concentration) (Lit.) EC50 (Photobacterium phosphoreum): 11 mg/l Exposure time: 15 min Test Type: microtox test Remarks: (IUCLID)

Hydrochloric Acid:

Toxicity to fish
LC50 (Gambusia affinis (Mosquito fish)): 282 mg/l Exposure time: 96 h Remarks: (IUCLID)

Persistence and degradability

Biodegradability
Remarks: No data available

Components:

acetic acid:

Biodegradability
Result: Readily biodegradable. Biodegradation: 99 % Exposure time: 30 d Method: OECD Test Guideline 301D Remarks: (HSDB) Result: Readily eliminated from water Biodegradation: 95 % Exposure time: 5 d Method: OECD Test Guideline 302B
Biochemical Oxygen Demand (BOD)
880 mg/g Incubation time: 5 d Remarks: (Lit.)
BOD/ThOD
76 % Remarks: (IUCLID)

Hydrochloric Acid:

Biodegradability
Remarks: The methods for determining the biological degradability are not applicable to inorganic substances.

Bioaccumulative potential

Bioaccumulation
Remarks: No data available

Components:

acetic acid:

Partition coefficient: noctanol/water
log Pow: -0.17 (25 °C) pH: 7 Method: (experimental) Remarks: Bioaccumulation is not expected. (ECHA)

Hydrochloric Acid:

Partition coefficient: noctanol/water
Remarks: Not applicable for inorganic substances

Mobility in soil

Stability in soil
Remarks: No data available

Other adverse effects

Components:

acetic acid:

Results of PBT and vPvB assessment
Substance does not meet the criteria for PBT or vPvB according to Regulation (EC) No 1907/2006, Annex XIII.

Hydrochloric Acid:

Results of PBT and vPvB assessment
Substance does not meet the criteria for PBT or vPvB according to Regulation (EC) No 1907/2006, Annex XIII.
Additional ecological information
May be harmful to aquatic organisms due to the shift of the pH. Do not empty into drains. Harmful effect due to pH shift. Discharge into the environment must be avoided.

SECTION 13: Disposal considerations

Disposal methods

Waste from residues
Offer surplus and non-recyclable solutions to a licensed disposal company.

SECTION 14: Transport information

International Regulations

IATA-DGR

UN/ID No. : UN 2920
Proper shipping name : Corrosive liquid, flammable, n.o.s.
(Hydrochloric Acid, acetic acid)
Class : 8
Subsidiary risk : 3
Packing group : II
Labels : Class 8 - Corrosive substances, Class 3 - Flammable liquids
Packing instruction (cargo aircraft) : 855
Packing instruction (passenger aircraft) : 851

IMDG-Code

UN number : UN 2920
Proper shipping name : CORROSIVE LIQUID, FLAMMABLE, N.O.S.
(Hydrochloric Acid, acetic acid)
Class : 8
Subsidiary risk : 3
Packing group : II
Labels : 8 (3)
EmS Code : F-E, S-C
Marine pollutant : no

Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

Not applicable for product as supplied.
National regulation GB 6944/12268
UN number : UN 2920
Proper shipping name : CORROSIVE LIQUID, FLAMMABLE, N.O.S.
(Hydrochloric Acid, acetic acid)
Class : 8
Subsidiary risk : 3
Packing group : II
Labels : 8 (3)

Special precautions for user

The transport classification(s) provided herein are for informational purposes only, and solely based upon the properties of the unpackaged material as it is described within this Safety Data Sheet. Transportation classifications may vary by mode of transportation, package sizes, and variations in regional or country regulations.

SECTION 15: Regulatory information

National regulatory information

Law on the Prevention and Control of Occupational Diseases

Regulations on Safety Management of Hazardous Chemicals

Catalogue of Hazardous Chemicals Identification of Major Hazard Installations for Hazardous Chemicals (GB 18218)

Listed

No. / Code Chemical name / Category Threshold quantity

W5.4 Flammable liquids 5,000 t

Hazardous Chemicals for Priority Management

Listed under SAWS

Regulations on Occupational Labor Protection in the at workplaces where

Toxic Substances Are Used

Catalogue of Highly Toxic Chemicals

Not listed

Regulation of Environmental Management on the First Import of Chemicals and the Import and Export of Toxic Chemicals

China Severely Restricted Toxic Chemicals for Import and Export

Not listed

Regulation on the Administration of Precursor Chemicals

Catalogue and Classification of Precursor Chemicals

Not listed

SECTION 16: Other information

Full text of other abbreviations

ACGIH
USA. ACGIH Threshold Limit Values (TLV)
GBZ 2.1-2007
Occupational exposure limits for hazardous agents in the workplace - Chemical hazardous agents.
ACGIH / TWA
8-hour, time-weighted average
ACGIH / STEL
Short-term exposure limit
ACGIH / C
Ceiling limit
GBZ 2.1-2007 / PC-TWA
Permissible concentration - time weighted average
GBZ 2.1-2007 / PC-STEL
Permissible concentration - short term exposure limit
GBZ 2.1-2007 / MAC AIIC - Australian Invent Transport by Land of Bra bw - Body weight; CMR Standard of the German List (Canada); ECx - Conc associated with x% respo Chemical Substances (Jap response; ERG - Emerge GLP - Good Laboratory P cer; IATA - International Construction and Equipm Half maximal inhibitory c tion; IECSC - Inventory o tional Maritime Dangerou Industrial Safety and H Standardization; KECI - K tration to 50 % of a test (Median Lethal Dose); MA lution from Ships; n.o.s. No Observed (Adverse) E fect Level; NOELR - No Norm; NTP - National Toxi icals; OECD - Organizatio fice of Chemical Safety a and Toxic substance; PIC stances; (Q)SAR - (Quant (EC) No 1907/2006 of th Registration, Evaluation, Accelerating Decompositi Chemical Substance Inve Thailand Existing Chemica States); UN - United Nat Transport of Dangerous WHMIS - Workplace Hazar
Maximum allowable concentration ry of Industrial Chemicals
ANTT - National Agency for il
ASTM - American Society for the Testing of Materials
- Carcinogen, Mutagen or Reproductive Toxicant
DIN nstitute for Standardisation
DSL - Domestic Substances ntration associated with x% response
ELx - Loading rate se
EmS - Emergency Schedule
ENCS - Existing and New n)
ErCx - Concentration associated with x% growth rate cy Response Guide
GHS - Globally Harmonized System
actice
IARC - International Agency for Research on Canir Transport Association
IBC - International Code for the nt of Ships carrying Dangerous Chemicals in Bulk
IC50 ncentration
ICAO - International Civil Aviation Organiza- Existing Chemical Substances in China
IMDG - Interna- Goods
IMO - International Maritime Organization
ISHL alth Law (Japan)
ISO - International Organisation for rea Existing Chemicals Inventory
LC50 - Lethal Concenopulation
LD50 - Lethal Dose to 50% of a test population POL - International Convention for the Prevention of Pol- Not Otherwise Specified
Nch - Chilean Norm
NO(A)EC fect Concentration
NO(A)EL - No Observed (Adverse) Efbservable Effect Loading Rate
NOM - Official Mexican ology Program
NZIoC - New Zealand Inventory of Chemfor Economic Co-operation and Development
OPPTS - Ofd Pollution Prevention
PBT - Persistent, Bioaccumulative S - Philippines Inventory of Chemicals and Chemical Subtative) Structure Activity Relationship
REACH - Regulation European Parliament and of the Council concerning the uthorisation and Restriction of Chemicals
SADT - Selfn Temperature
SDS - Safety Data Sheet
TCSI - Taiwan tory
TDG - Transportation of Dangerous Goods
TECI s Inventory
TSCA - Toxic Substances Control Act (United ons
UNRTDG - United Nations Recommendations on the oods
vPvB - Very Persistent and Very Bioaccumulative
ous Materials Information System
Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

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