Chemical Safety Data Sheet MSDS / SDS

Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide

Revision Date:2023-07-15Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide
  • CBnumber: CB9458631
  • CAS: 75980-60-8
  • EINECS Number: 278-355-8
  • Synonyms: Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide,PHOTOINITIATOR TPO

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 400-158-6606

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Symbol(GHS)
  • Signal wordWarning
Precautionary statements
P501 Dispose of contents/container to..…
P405 Store locked up.
P391 Collect spillage. Hazardous to the aquatic environment
P308+P313 IF exposed or concerned: Get medical advice/attention.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P273 Avoid release to the environment.
P272 Contaminated work clothing should not be allowed out of the workplace.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P202 Do not handle until all safety precautions have been read and understood.
P201 Obtain special instructions before use.
Hazard statements
H411 Toxic to aquatic life with long lasting effects
H361 Suspected of damaging fertility or the unborn child
H317 May cause an allergic skin reaction

SECTION 3: Composition/information on ingredients

Substance

  • Product name: Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide
  • Synonyms: Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide,PHOTOINITIATOR TPO
  • CAS: 75980-60-8
  • EC number: 278-355-8
  • MF: C22H21O2P
  • MW: 348.37

SECTION 4: First aid measures

Description of first aid measures

General advice
Show this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Call in physician.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.
In case of eye contact
After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.
If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.

Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11

Indication of any immediate medical attention and special treatment needed

No data available

SECTION 5: Firefighting measures

Extinguishing media

Suitable extinguishing media
Water Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.

Special hazards arising from the substance or mixture

Carbon oxides Oxides of phosphorus Combustible.

Development of hazardous combustion gases or vapours possible in the event of fire.

Advice for firefighters

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

Further information

Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.

For personal protection see section 8.

Environmental precautions

Do not let product enter drains.

Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid generation of dusts.

Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

Precautions for safe handling

For precautions see section 2.2.

Conditions for safe storage, including any incompatibilities

Storage conditions

Tightly closed. Dry.

Light sensitive.

Specific end use(s)

Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

control parameter

Hazard composition and occupational exposure limits
Does not contain substances with occupational exposure limits.

Exposure controls

Personal protective equipment
Eye/face protection

Use equipment for eye protection tested and approved under appropriate

government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Body Protection

protective clothing

Respiratory protection

required when dusts are generated.

Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.

Recommended Filter type: Filter type P3

The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.

These measures have to be properly documented.

Control of environmental exposure

Do not let product enter drains.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • AppearanceForm: solid
  • Odourweak characteristic odour
  • Odour ThresholdDo not attempt to smell the product as it is hazardous. d) pH 6,4 - 6,9 at 20 °C Melting point/freezing point Initial boiling point and boiling range Melting point/range: 88 - 92 °C - lit. No data available Flash point Not applicableNot applicable Evaporation rate No data available Flammability (solid, gas) Upper/lower flammability or explosive limits No data available No data available Vapour pressure< 0,01 hPa at 25 °C Vapour density No data available Relative density 1,218 at 20 °C - OECD Test Guideline 109 Water solubility ca.0,011 g/l at 20 °C - OECD Test Guideline 105 Partition coefficient: n-octanol/water Autoignition temperature Decomposition temperature log Pow: 3,1 at 23 °C - Bioaccumulation is not expected. does not ignite No data available Viscosity Viscosity, kinematic: No data available Viscosity, dynamic: No data available Explosive properties No data available Oxidizing properties No data available
  • Melting point/freezing pointMelting point/range: 88 - 92 °C - lit.
  • Initial boiling point and boiling range88-92 °C(lit.)
  • Flash pointNot applicableNot applicable
  • Evaporation rate>230 °F
  • Flammability (solid, gas)No data available
  • Upper/lower flammability or explosive limitsNo data available
  • Vapour pressure< 0,01 hPa at 25 °C
  • Vapour density No data available
  • Relative density1,218 at 20 °C - OECD Test Guideline 109
  • Water solubilityca.0,011 g/l at 20 °C - OECD Test Guideline 105
  • Partition coefficient: n-octanol/waterlog Pow: 3,1 at 23 °C - Bioaccumulation is not expected.
  • Autoignition temperaturedoes not ignite
  • Decomposition temperatureNo data available
  • ViscosityViscosity, kinematic: No data available Viscosity, dynamic: No data available
  • Explosive propertiesNo data available
  • Oxidizing propertiesNo data available
  • λmax400nm(DMF)(lit.)

Other safety information

No data available

SECTION 10: Stability and reactivity

Reactivity

The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .

Possibility of hazardous reactions

No data available

Conditions to avoid

no information available

Incompatible materials

Strong oxidizing agents

Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

Information on toxicological effects

Acute toxicity
LD50 Oral - Rat - male and female - > 5.000 mg/kg (OECD Test Guideline 401)
Inhalation
LD50 Dermal Dermal - Rat - male and female - > 2.000 mg/kg (OECD Test Guideline 402)
Skin corrosion/irritation
Skin - Rabbit
Result: No skin irritation - 24 h Remarks: (ECHA)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: No eye irritation (Draize Test)
Respiratory or skin sensitization
(OECD Test Guideline 429)
Germ cell mutagenicity
Test Type: Mutagenicity (mammal cell test): chromosome aberration. Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 473 Result: negative
Test Type: In vitro mammalian cell gene mutation test Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 476
Result: negative
Test Type: Ames test
Test system: Escherichia coli/Salmonella typhimurium Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471
Result: negative
Carcinogenicity
No data available
Reproductive toxicity
Suspected of damaging fertility.
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available

SECTION 12: Ecological information

Toxicity

Toxicity to fish
semi-static test LC50 - Oryzias latipes (Orange-red killifish) - 6,53 mg/l - 48 h

Remarks: (ECHA)


Toxicity to daphnia and other aquatic invertebrates

static test EC50 - Daphnia magna (Water flea) - 3,53 mg/l - 48 h (OECD Test Guideline 202)

Toxicity to algae
static test EC10 - Pseudokirchneriella subcapitata (green algae) - 1,56 mg/l - 72 h

(OECD Test Guideline 201)

static test EC50 - Pseudokirchneriella subcapitata (green algae) - > 2,01 mg/l - 72 h

(OECD Test Guideline 201)

Toxicity to bacteria
static test EC50 - activated sludge - > 1.000 mg/l - 3 h (OECD Test Guideline 209)

Remarks: (above the solubility limit in the test medium)


Persistence and degradability

Biodegradability aerobic - Exposure time 28 d

Result: 0 - 10 % - Not readily biodegradable. (OECD Test Guideline 301F)

Bioaccumulative potential

Bioaccumulation Cyprinus carpio (Carp) - 56 d

at 25 °C(Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide)


Bioconcentration factor (BCF): 23 - 55 Remarks: (External MSDS)


Mobility in soil

No data available

Results of PBT and vPvB assessment

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

Other adverse effects

No data available

SECTION 13: Disposal considerations

Waste treatment methods

Product

See www.retrologistik.com for processes regarding the return of chemicals and

containers, or contact us there if you have further questions.

SECTION 14: Transport information

UN number

ADR/RID: 3077 IMDG: 3077 IATA: 3077

UN proper shipping name

ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (Diphenyl(2,4,6-

trimethylbenzoyl)phosphine oxide)

IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (Diphenyl(2,4,6-

trimethylbenzoyl)phosphine oxide)


14.3

IATA: Environmentally hazardous substance, solid, n.o.s. trimethylbenzoyl)phosphine oxide)

Transport hazard class(es)

(Diphenyl(2,4,6-


ADR/RID: 9 IMDG: 9

IATA: 9

14.4

Packaging group

ADR/RID: III IMDG: III


IATA: III

14.5

Environmental hazards

ADR/RID: yes IMDG Marine pollutant: yes


IATA: yes

14.6

Special precautions for user



Further information


EHS-Mark required (ADR 2.2.9.1.10, IMDG code 2.10.3) for single packagings and combination packagings containing inner packagings with Dangerous Goods > 5L for liquids or > 5kg for solids.Packages smaller than or equal to 5 kg / L , not dangerous goods of Class 9

SECTION 15: Regulatory information

Safety, health and environmental regulations/legislation specific for the substance or mixture

Regulations on the Safety Management of Hazardous Chemicals
China Catalog of Hazardous chemicals 2015:Not Listed. website: https://www.mem.gov.cn/
Measures for Environmental Management of New Chemical Substances
Vietnam National Chemical Inventory:Listed. website: https://chemicaldata.gov.vn/
United States Toxic Substances Control Act (TSCA) Inventory:Listed. website: https://www.epa.gov/
Philippines Inventory of Chemicals and Chemical Substances (PICCS):Listed. website: https://emb.gov.ph/
New Zealand Inventory of Chemicals (NZIoC):Listed. website: https://www.epa.govt.nz/
Korea Existing Chemicals List (KECL):Listed. website: http://ncis.nier.go.kr
European Inventory of Existing Commercial Chemical Substances (EINECS):Listed. website: https://echa.europa.eu/
EC Inventory:Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC):Listed. website: https://www.mee.gov.cn/

SECTION 16: Other information

Abbreviations and acronyms

  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • CAS: Chemical Abstracts Service
  • EC50: Effective Concentration 50%
  • IATA: International Air Transportation Association
  • IMDG: International Maritime Dangerous Goods
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • STEL: Short term exposure limit
  • TWA: Time Weighted Average

References

【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple

【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp

【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/

【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en

【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg

【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp

【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm

【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/

【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home

【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/

Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

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