Chemical Safety Data Sheet MSDS / SDS

ETHYL 3-METHYL-2-OXOBUTYRATE

Revision Date:2024-03-02Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: ETHYL 3-METHYL-2-OXOBUTYRATE
  • CBnumber: CB3272529
  • CAS: 20201-24-5
  • EINECS Number: 243-587-0
  • Synonyms: ethyl dimethylpyruvate,ETHYL 3-METHYL-2-OXOBUTYRATE

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 400-158-6606

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Symbol(GHS)
  • Signal wordWarning
Precautionary statements
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P240 Ground/bond container and receiving equipment.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
Hazard statements
H226 Flammable liquid and vapour

SECTION 3: Composition/information on ingredients

Substance

  • Product name: ETHYL 3-METHYL-2-OXOBUTYRATE
  • Synonyms: ethyl dimethylpyruvate,ETHYL 3-METHYL-2-OXOBUTYRATE
  • CAS: 20201-24-5
  • EC number: 243-587-0
  • MF: C7H12O3
  • MW: 144.17

SECTION 4: First aid measures

Description of first aid measures

General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Flush eyes with water as a precaution.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11

Indication of any immediate medical attention and special treatment needed

No data available

SECTION 5: Firefighting measures

Extinguishing media

Suitable extinguishing media
Dry powder Dry sand
Unsuitable extinguishing media
Do NOT use water jet.

Special hazards arising from the substance or mixture

Carbon oxides

Advice for firefighters

Wear self-contained breathing apparatus for firefighting if necessary.

Further information

Use water spray to cool unopened containers.

NFPA 704

0
2
0
HEALTH 0 Poses no health hazard, no precautions necessary and would offer no hazard beyond that of ordinary combustible materials
FIRE 2 Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur and multiple finely divided suspended solids that do not require heating before ignition can occur. Flash point between 37.8 and 93.3 °C (100 and 200 °F). (e.g. diesel fuel, sulfur)
REACT 0 Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)
SPEC. HAZ.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Avoid breathing vapours, mist or gas. Remove all sources of ignition. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas.

For personal protection see section 8.

Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains.

Methods and materials for containment and cleaning up

Contain spillage, and then collect with non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite) and place in container for disposal according to local / national regulations (see section 13).

Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

Precautions for safe handling

Avoid inhalation of vapour or mist.

Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge.

For precautions see section 2.2.

Conditions for safe storage, including any incompatibilities

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Store in cool place.

Recommended storage temperature 2 - 8 °C

Specific end use(s)

Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

control parameter

Hazard composition and occupational exposure limits
Does not contain substances with occupational exposure limits.

Exposure controls

Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

Personal protective equipment
Eye/face protection

Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.

The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.

Body Protection

Impervious clothing, Flame retardant antistatic protective clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection

Where risk assessment shows air-purifying respirators are appropriate use a full- face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Control of environmental exposure

Prevent further leakage or spillage if safe to do so. Do not let product enter drains.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • Appearancelight yellow clear, liquid
  • OdourNo data available
  • Odour ThresholdNo data available
  • pHNo data available
  • Melting point/freezing pointNo data available
  • Initial boiling point and boiling range62 °C at 15 hPa - lit.
  • Flash point43 °C - closed cup
  • Evaporation rateNo data available
  • Flammability (solid, gas)No data available
  • Upper/lower flammability or explosive limitsNo data available
  • Vapour pressureNo data available
  • Vapour densityNo data available
  • Relative density0,989 g/cm3 at 25 °C
  • Water solubilityNo data available
  • Partition coefficient: n-octanol/waterNo data available
  • Autoignition temperatureNo data available
  • Decomposition temperatureNo data available
  • ViscosityNo data available
  • Explosive propertiesNo data available
  • Oxidizing propertiesNo data available

Other safety information

No data available

SECTION 10: Stability and reactivity

Reactivity

No data available

Chemical stability

Stable under recommended storage conditions.

Possibility of hazardous reactions

No data available

Conditions to avoid

Heat, flames and sparks.

Incompatible materials

Strong oxidizing agents, Strong bases

Hazardous decomposition products

Hazardous decomposition products formed under fire conditions. - Carbon oxides Other decomposition products - No data available

In the event of fire: see section 5

SECTION 11: Toxicological information

Information on toxicological effects

Acute toxicity
No data available
Skin corrosion/irritation
No data available
Serious eye damage/eye irritation
No data available
Respiratory or skin sensitisation
No data available
Germ cell mutagenicity
No data available
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
Additional Information
RTECS: Not available
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.

SECTION 12: Ecological information

Toxicity

No data available

Persistence and degradability

No data available

Bioaccumulative potential

No data available

Mobility in soil

No data available

Results of PBT and vPvB assessment

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

Other adverse effects

No data available

SECTION 13: Disposal considerations

Waste treatment methods

Product

Offer surplus and non-recyclable solutions to a licensed disposal company. Waste material must be disposed of in accordance with the Directive on waste 2008/98/EC as well as other national and local regulations. Leave chemicals in original containers. No mixing with other waste. Handle uncleaned containers like the product itself.

Contaminated packaging

Dispose of as unused product.

SECTION 14: Transport information

SECTION 14: Transport information

UN number

ADR/RID:IMDG:IATA:ADR/RID:IMDG:IATA:
IATA:

UN number

ADR/RID: 2570 IMDG: 2570 IATA: 2570
ADR/RID: 1759 IMDG: 1759 IATA: 1759
ADR/RID: 3077 IMDG: 3077 IATA: 3077
ADR/RID: 3077 IMDG: 3077 IATA: 3077
ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1
ADR/RID: - IMDG: - IATA: -
ADR/RID: - IMDG: - IATA: -
ADR/RID: 1301 IMDG: 1301 IATA: 1301
ADR/RID: 3272 IMDG: 3272 IATA: 3272
ADR/RID: 0000 IMDG: 0000 IATA: 0000

UN proper shipping name

ADR/RID: Not permitted for transport IMDG: Not permitted for transport IATA: “unable to ship at this time” Passenger Aircraft: Not permitted for transport Cargo Aircraft: Not permitted for transport
ADR/RID: ESTERS, N.O.S. (Ethyl valerate) IMDG: ESTERS, N.O.S. (Ethyl valerate) IATA: Esters, n.o.s. (Ethyl valerate)
ADR/RID: VINYL ACETATE, STABILIZED IMDG: VINYL ACETATE, STABILIZED IATA: Vinyl acetate, stabilized
ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA: Not dangerous goods
ADR/RID: - IMDG: - IATA: -
ADR/RID: II IMDG: II IATA: II
ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. ((R)-(+)-N-Boc- 3-pyrrolidinol) IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. ((R)-(+)-N-Boc- IATA: Environmentally hazardous substance, solid, n.o.s. pyrrolidinol)
ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (4,4',4''-(Ethan- 1,1,1-triyl)triphenol) IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (4,4',4''-(Ethan- 1,1,1-triyl)triphenol) IATA: Environmentally hazardous substance, solid, n.o.s. triyl)triphenol) (4,4',4''-(Ethan-1,1,1-
ADR/RID: CORROSIVE SOLID, N.O.S. (Trioxysalen) IMDG: CORROSIVE SOLID, N.O.S. (Trioxysalen) IATA: Corrosive solid, n.o.s. (Trioxysalen)
ADR/RID: CADMIUM COMPOUND (Cadmium chloride hydrate) IMDG: CADMIUM COMPOUND (Cadmium chloride hydrate) IATA: Cadmium compound (Cadmium chloride hydrate)

Transport hazard class(es)

ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1
ADR/RID: 8 IMDG: 8 IATA: 8
ADR/RID: 9 IMDG: 9 IATA: 9
((R)-(+)-N-Boc-3- ADR/RID: 9 IMDG: 9 IATA: 9
ADR/RID: yes IMDG Marine pollutant: yes IATA: no
ADR/RID: no IMDG Marine pollutant: no IATA: no
ADR/RID: - IMDG: - IATA: -
ADR/RID: 3 IMDG: 3 IATA: 3
ADR/RID: 3 IMDG: 3 IATA: 3
ADR/RID: NON IMDG: NON IATA: NON

Packaging group

ADR/RID: - IMDG: - IATA: -
ADR/RID: III IMDG: III IATA: III
ADR/RID: II IMDG: II IATA: II
ADR/RID: - IMDG: - IATA: -
No data available
No data available
ADR/RID: III IMDG: III IATA: III
ADR/RID: III IMDG: III IATA: III
ADR/RID: II IMDG: II IATA: II
ADR/RID: III IMDG: III IATA: III

Environmental hazards

ADR/RID: no IMDG Marine pollutant: no IATA: no
ADR/RID: yes IMDG Marine pollutant: yes IATA: yes Special precautions for user Further information EHS-Mark required (ADR 2.2.9.1.10, IMDG code 2.10.3) for single packagings and combination packagings containing inner packagings with Dangerous Goods > 5L for liquids or > 5kg for solids.Packages smaller than or equal to 5 kg / L , not dangerous goods of Class 9
ADR/RID: yes IMDG Marine pollutant: yes IATA: yes 3-pyrrolidinol) Special precautions for user Further information EHS-Mark required (ADR 2.2.9.1.10, IMDG code 2.10.3) for single packagings and combination packagings containing inner packagings with Dangerous Goods > 5L for liquids or > 5kg for solids.
ADR/RID: no IMDG Marine pollutant: no IATA: no
ADR/RID: no IMDG Marine pollutant: no IATA: no Special precautions for user No data available
ADR/RID: no IMDG Marine pollutant: no IATA: no
ADR/RID: no IMDG Marine pollutant: no IATA: no

Special precautions for user

Further information Unable to ship at this time, further testing needed.
No data available
No data available
No data available

SECTION 15: Regulatory information

Safety, health and environmental regulations/legislation specific for the substance or mixture

Regulations on the Safety Management of Hazardous Chemicals
China Catalog of Hazardous chemicals 2015:Not Listed. website: https://www.mem.gov.cn/
Measures for Environmental Management of New Chemical Substances
United States Toxic Substances Control Act (TSCA) Inventory:Not Listed. website: https://www.epa.gov/
Philippines Inventory of Chemicals and Chemical Substances (PICCS):Not Listed. website: https://emb.gov.ph/
New Zealand Inventory of Chemicals (NZIoC):Not Listed. website: https://www.epa.govt.nz/
Korea Existing Chemicals List (KECL):Not Listed. website: http://ncis.nier.go.kr
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC):Not Listed. website: https://www.mee.gov.cn/
Vietnam National Chemical Inventory:Listed. website: https://chemicaldata.gov.vn/
European Inventory of Existing Commercial Chemical Substances (EINECS):Listed. website: https://echa.europa.eu/
EC Inventory:Listed.

SECTION 16: Other information

Abbreviations and acronyms

  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • CAS: Chemical Abstracts Service
  • EC50: Effective Concentration 50%
  • IATA: International Air Transportation Association
  • IMDG: International Maritime Dangerous Goods
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • STEL: Short term exposure limit
  • TWA: Time Weighted Average

References

【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple

【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp

【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/

【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en

【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg

【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp

【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm

【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/

【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home

【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/

Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

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