11.1 Information on toxicological effects
Mixture Acute toxicity
Acute toxicity estimate Oral - 51.8 mg/kg (Calculation method)
Symptoms: If ingested, severe burns of the mouth and throat, as well as a danger of perforation of the esophagus and the stomach.
Acute toxicity estimate Inhalation - 4 h - 2.5 mg/l - vapor(Calculation method)
Symptoms: mucosal irritations, Cough, Shortness of breath, Possible damages:, damage of respiratory tract
LD50 Dermal - 300 mg/kg
Skin corrosion/irritation
Remarks: Mixture causes burns.
Serious eye damage/eye irritation
Remarks: Mixture causes serious eye damage.
Risk of blindness!
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
Fluoride ion can reduce serum calcium levels possibly causing fatal hypocalcemia.
Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice.
Components Dihydrogen hexafluorotitanate(2-)
Acute toxicity
LD50 Oral - 100 mg/kg
Remarks: No data available
LC50 Inhalation - 4 h - 3 mg/l - vapor (Acute toxicity estimate)
Remarks: No data available
LD50 Dermal - 300 mg/kg
Remarks: No data available
Skin corrosion/irritation
Remarks: No data available
Serious eye damage/eye irritation
Remarks: No data available
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
Hydrofluoric acid
Acute toxicity
Oral: No data available
LC50 Inhalation - Rat - 1 h - 1.34 mg/l - vapor
Remarks: (IUCLID)
Acute toxicity estimate Inhalation - 0.6 mg/l - vapor (Expert judgment)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Symptoms: burns of mucous membranes, Cough, Shortness of breath, Pos- sible damages:, damage of respiratory tract, Resultant lesions may af- fectthe following:, bronchitis, Pneumonia, Lung edema
Acute toxicity estimate Dermal - 5.1 mg/kg (Expert judgment)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Skin corrosion/irritation
Skin - Rabbit
Result: Causes burns. - 4 h (OECD Test Guideline 404)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Remarks: Symptoms may be delayed.
Possible damages:
Necrosis
Tendency of poor wound-healing after penetration of the substance.
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Causes burns.
(OECD Test Guideline 405)
Remarks: (IUCLID)
Remarks: Causes serious eye damage.
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Test Type: Ames test
Test system: S. typhimurium
Result: negative
Test Type: Chromosome aberration test in vitro
Test system: Chinese hamster ovary cells
Result: Positive results were obtained in some in vitro tests.
Species: Rat
Remarks: Cytogenetic analysis
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Acute inhalation toxicity - burns of mucous membranes, Cough, Shortness of breath, Possible damages:, damage of respiratory tract, Resultant lesions may affectthe following:, bronchitis, Pneumonia, Lung edema
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2