Methyl formate
Product identifier
- Product name: Methyl formate
- CBnumber: CB9106448
- CAS: 107-31-3
- EINECS Number: 203-481-7
- Synonyms: methyl formate,HCOOCH3
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
Substance
- Product name: Methyl formate
- Synonyms: methyl formate,HCOOCH3
- CAS: 107-31-3
- EC number: 203-481-7
- MF: C2H4O2
- MW: 60.05
Description of first aid measures
General adviceMost important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
Extinguishing media
Suitable extinguishing mediaSpecial hazards arising from the substance or mixture
Carbon oxides Combustible.
Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
Further information
Use water spray to cool unopened containers.
NFPA 704
| HEALTH | 2 | Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine) | |
| FIRE | 4 | Will rapidly or completely vaporize at normal atmospheric pressure and temperature, or is readily dispersed in air and will burn readily. Includes pyrophoric substances. Flash point below room temperature at 22.8 °C (73 °F). (e.g. acetylene, propane, hydrogen gas) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Wear respiratory protection. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapors accumulating to form explosive concentrations. Vapors can accumulate in low areas.
For personal protection see section 8.
Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
Methods and materials for containment and cleaning up
Contain spillage, and then collect with non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite) and place in container for disposal according to local / national regulations (see section 13).
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Advice on safe handling
Avoid contact with skin and eyes. Avoid inhalation of vapor or mist.
Advice on protection against fire and explosion
Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge.
Hygiene measures
Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Storage conditions
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Store in cool place.
Over time, pressure may increase causing containers to burst Refrigerate before opening.
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
control parameter
Hazard composition and occupational exposure limitsExposure controls
Personal protective equipmentFace shield and safety glasses Use equipment for eye protection tested and
approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
Splash contact Material: butyl-rubber
Minimum layer thickness: 0,3 mm Break through time: 145 min
Material tested:Butoject? (KCL 897 / Aldrich Z677647, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the EC approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Complete suit protecting against chemicals, Flame retardant antistatic protective clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Where risk assessment shows air-purifying respirators are appropriate use a full- face respirator with multi-purpose combination (US) or type AXBEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and
components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
Information on basic physicochemical properties
- Appearancecolorless liquid
- OdourNo data available
- Odour Threshold130ppm
- Melting point/freezing pointMelting point/range: -100 °C - lit.
- Initial boiling point and boiling range32 - 34 °C - lit.
- Flash point-19 °C - closed cup
- Evaporation rate−16 °F
- Flammability (solid, gas)No data available
- Upper/lower flammability or explosive limits Upper explosion limit: 23 %(V) Lower explosion limit: 5 %(V)
- Vapour pressure 634,9 hPa at 20 °C 2.261,5 hPa at 55 °C
- Vapour density 2,07 - (Air = 1.0)
- Relative density2.1 (vs air)
- Water solubilitysoluble
- Partition coefficient: n-octanol/waterlog Pow: -0,21
- Autoignition temperatureNo data available
- Decomposition temperatureNo data available
- ViscosityViscosity, kinematic: No data available Viscosity, dynamic: No data available
- Explosive propertiesNo data available
- Oxidizing propertiesNo data available
- Henry's Law Constant0.90 at 5.00 °C, 1.18 at 10.00 °C, 1.51 at 15.00 °C, 1.91 at 20.00 °C, 2.36 at 25.00 °C (column stripping-UV, Kutsuna et al., 2005)
- λmaxλ: 259 nm Amax: 1.00
λ: 260 nm Amax: 0.70
λ: 265 nm Amax: 0.20
λ: 270 nm Amax: 0.04
λ: 310-400 nm Amax: 0.01
Other safety information
Relative vapor density
2,07 - (Air = 1.0)
Reactivity
No data available
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
No data available
Conditions to avoid
Heat, flames and sparks.
Incompatible materials
Oxidizing agents
Hazardous decomposition products
In the event of fire: see section 5
Information on toxicological effects
Acute toxicityAcute toxicity estimate Inhalation - 3,1 mg/l (Expert judgment)
Acute toxicity estimate Dermal - 300,1 mg/kg (Expert judgment)
Result: No skin irritation (OECD Test Guideline 404)
Test Type: Ames test
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471
Result: negative
Toxicity
static test EC50 - Daphnia magna (Water flea) - > 500 mg/l - 48 h (OECD Test Guideline 202)
Persistence and degradability
Biodegradability aerobic - Exposure time 28 d
Result: 93 % - Readily biodegradable. (OECD Test Guideline 310)
Bioaccumulative potential
No data available
Mobility in soil
No data available
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
No data available
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Waste material must be disposed of in accordance with the Directive on waste 2008/98/EC as well as other national and local regulations. Leave chemicals in original containers. No mixing with other waste. Handle uncleaned containers like the product itself.
IncompatibilitiesMay form explosive mixture with air. Incompatible with oxidizers; contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Incompatible with arsenic compounds (releases hydrogen cyanide gas), diazo compounds, dithiocarbamates isocyanates, mercaptans, nitrides, and sulfides, thiosulfates and dithionites .
Waste DisposalIncineration; atomizing in a suitable combustion chamber.
Contaminated packaging
Dispose of as unused product.
UN number
UN proper shipping name
Transport hazard class(es)
ADR/RID: 3 IMDG: 3 IATA: 3
Packaging group
ADR/RID: I IMDG: I IATA: I
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
Special precautions for user
No data available
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous ChemicalsAbbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
Other Information
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.