Chemical Safety Data Sheet MSDS / SDS

Sodium thioglycolate

Revision Date:2024-11-09Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: Sodium thioglycolate
  • CBnumber: CB2113072
  • CAS: 367-51-1
  • EINECS Number: 206-696-4
  • Synonyms: Sodium Thioglycolate,Sodium Thioglycollate

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 400-158-6606

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Symbol(GHS)
  • Signal wordWarning
Precautionary statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P405 Store locked up.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
Hazard statements
H319 Causes serious eye irritation
H317 May cause an allergic skin reaction
H315 Causes skin irritation
H311 Toxic in contact with skin
H302 Harmful if swallowed

SECTION 3: Composition/information on ingredients

Substance

  • Product name: Sodium thioglycolate
  • Synonyms: Sodium Thioglycolate,Sodium Thioglycollate
  • CAS: 367-51-1
  • EC number: 206-696-4
  • MF: C2H5NaO2S
  • MW: 116.11

SECTION 4: First aid measures

Description of first aid measures

General advice
Show this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.
In case of eye contact
After eye contact: rinse out with plenty of water. Remove contact lenses.
If swallowed
If swallowed: give water to drink (two glasses at most). Seek medical advice immediately. In exceptional cases only, if medical care is not available within one hour, induce vomiting (only in persons who are wide awake and fully conscious), administer activated charcoal (20 - 40 g in a 10% slurry) and consult a doctor as quickly as possible.

Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11

Indication of any immediate medical attention and special treatment needed

No data available

SECTION 5: Firefighting measures

Extinguishing media

Suitable extinguishing media
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.

Special hazards arising from the substance or mixture

Carbon oxides Sulfur oxides Sodium oxides Not combustible.

Ambient fire may liberate hazardous vapours.

Advice for firefighters

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

Further information

Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.

NFPA 704

3
1
1
HEALTH 3 Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid)
FIRE 1 Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia)
REACT 1 Normally stable, but can become unstable at elevated temperatures and pressures (e.g. propene)
SPEC. HAZ.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.

For personal protection see section 8.

Environmental precautions

Do not let product enter drains.

Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully. Dispose of properly. Clean up affected area. Avoid generation of dusts.

Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

Precautions for safe handling

For precautions see section 2.2.

Conditions for safe storage, including any incompatibilities

Storage conditions

Tightly closed. Dry. Keep in a well-ventilated place. Keep locked up or in an area accessible

only to qualified or authorized persons.

Storage stability

Recommended storage temperature

-20 °C

Store under inert gas. hygroscopic Stench.

Specific end use(s)

Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

control parameter

Hazard composition and occupational exposure limits
Does not contain substances with occupational exposure limits.

Exposure controls

Personal protective equipment
Eye/face protection

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Skin protection

This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Full contact

Material: Nitrile rubber

Minimum layer thickness: 0,11 mm Break through time: 480 min

Material tested:KCL 741 Dermatril? L

This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Splash contact Material: Nitrile rubber

Minimum layer thickness: 0,11 mm Break through time: 480 min

Material tested:KCL 741 Dermatril? L

Body Protection

protective clothing

Respiratory protection

required when dusts are generated.

Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.

Recommended Filter type: Filter type P3

The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.

These measures have to be properly documented.

Control of environmental exposure

Do not let product enter drains.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • Appearance solid
  • Odourputrid
  • Odour ThresholdNo data available
  • pH6,7 at 100 g/l at 20 °C - DIN 19268
  • Melting point/freezing pointMelting point/range: >300 °C
  • Initial boiling point and boiling rangeNo data available
  • Flash pointNo data available
  • Evaporation rateNo data available
  • Flammability (solid, gas)The product is not flammable. - Flammability (solids)
  • Upper/lower flammability or explosive limitsNo data available
  • Vapour pressure< 0,1 hPa at 25 °C - (External MSDS)
  • Vapour density No data available
  • Relative densityNo data available
  • Water solubilityca.609,1 g/l at 20 °C - OECD Test Guideline 105
  • Partition coefficient: n-octanol/waterlog Pow: -3,78 - (Lit.), Bioaccumulation is not expected.
  • Autoignition temperatureNo data available
  • Decomposition temperatureNo data available
  • ViscosityViscosity, kinematic: No data available Viscosity, dynamic: No data available
  • Explosive propertiesNo data available
  • Oxidizing propertiesNo data available

Other safety information

No data available

SECTION 10: Stability and reactivity

Reactivity

No data available

Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) . Exposure to moisture.

Possibility of hazardous reactions

No data available

Conditions to avoid

Exposure to moisture. no information available

Incompatible materials

Metals

Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

Information on toxicological effects

Acute toxicity
LD50 Oral - Rat - male and female - 50 - 200 mg/kg (OECD Test Guideline 423)
Symptoms: Nausea, Vomiting
LC50 Inhalation - Rat - male and female - 4 h - > 2.729 mg/l (OECD Test Guideline 403)
LD50 Dermal - Rat - female - > 1.000 - 2.000 mg/kg (OECD Test Guideline 402)
Skin corrosion/irritation
Skin - Rabbit
Result: slight irritation - 4 h (OECD Test Guideline 404)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: slight irritation (OECD Test Guideline 405)
Respiratory or skin sensitization
(OECD Test Guideline 429)
Germ cell mutagenicity
Test Type: Ames test
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471
Result: negative
Test Type: In vivo micronucleus test Species: Mouse
Cell type: Bone marrow Application Route: Oral
Method: OECD Test Guideline 474 Result: negative
Carcinogenicity
No data available
Reproductive toxicity
Specific target organ toxicity - single exposure Specific target organ toxicity - repeated exposure Aspiration hazard
Toxicity
LD50 i.p. in rats: 148 mg/kg, Freeman, Rosenthal, Fed. Proc. 11, 347 (1952)

SECTION 12: Ecological information

Toxicity

Toxicity to fish
flow-through test LC50 - Oncorhynchus mykiss (rainbow trout) - > 100 mg/l - 96 h

(OECD Test Guideline 203)

Remarks: The value is given in analogy to the following substances: 2-Thioglycolic acid


Toxicity to daphnia and other aquatic invertebrates

static test EC50 - Daphnia magna (Water flea) - 38 mg/l - 48 h (OECD Test Guideline 202)

Remarks: The value is given in analogy to the following substances: 2-Thioglycolic acid


Toxicity to algae
ErC50 - Desmodesmus subspicatus (green algae) - > 100 mg/l - 72 h

(OECD Test Guideline 201)

Remarks: The value is given in analogy to the following substances: diammonium dithiodiglycolate


Toxicity to bacteria
static test EC50 - activated sludge - 820 mg/l - 0,5 h

(OECD Test Guideline 209)

Remarks: The value is given in analogy to the following substances:

Ammonium thioglycolate


Persistence and degradability

Biodegradability Result: - Readily biodegradable.

Bioaccumulative potential

Mobility in soil

Results of PBT and vPvB assessment

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

Other adverse effects

SECTION 13: Disposal considerations

Waste treatment methods

Product

See www.retrologistik.com for processes regarding the return of chemicals and

containers, or contact us there if you have further questions.

SECTION 14: Transport information

UN number

ADR/RID: 2811 IMDG: 2811 IATA: 2811

UN proper shipping name

ADR/RID: TOXIC SOLID, ORGANIC, N.O.S. (sodium thioglycolate) IMDG: TOXIC SOLID, ORGANIC, N.O.S. (sodium thioglycolate) IATA: Toxic solid, organic, n.o.s. (sodium thioglycolate)

Transport hazard class(es)

ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1

Packaging group

ADR/RID: III IMDG: III IATA: III

Environmental hazards

ADR/RID: no IMDG Marine pollutant: no IATA: no

Special precautions for user

No data available

SECTION 15: Regulatory information

Safety, health and environmental regulations/legislation specific for the substance or mixture

Regulations on the Safety Management of Hazardous Chemicals
China Catalog of Hazardous chemicals 2015:Not Listed. website: https://www.mem.gov.cn/
Measures for Environmental Management of New Chemical Substances
Philippines Inventory of Chemicals and Chemical Substances (PICCS):Not Listed. website: https://emb.gov.ph/
Vietnam National Chemical Inventory:Listed. website: https://chemicaldata.gov.vn/
United States Toxic Substances Control Act (TSCA) Inventory:Listed. website: https://www.epa.gov/
New Zealand Inventory of Chemicals (NZIoC):Listed. website: https://www.epa.govt.nz/
Korea Existing Chemicals List (KECL):Listed. website: http://ncis.nier.go.kr
European Inventory of Existing Commercial Chemical Substances (EINECS):Listed. website: https://echa.europa.eu/
EC Inventory:Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC):Listed. website: https://www.mee.gov.cn/

SECTION 16: Other information

Abbreviations and acronyms

  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • CAS: Chemical Abstracts Service
  • EC50: Effective Concentration 50%
  • IATA: International Air Transportation Association
  • IMDG: International Maritime Dangerous Goods
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • STEL: Short term exposure limit
  • TWA: Time Weighted Average

References

【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple

【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp

【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/

【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en

【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg

【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp

【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm

【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/

【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home

【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/

Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

Recommended Products
Sodium benzoate SDS Sodium acetate SDS Sodium thioglycolate SDS 2-Mercaptobenzothiazole SDS Diphenolic acid SDS 4-(Diethylamino)salicylaldehyde SDS Sodium chloride SDS 2-Mercaptoethanol SDS 2,2'-Thiodiethanol SDS Sodium glycolate SDS