Chemical Safety Data Sheet MSDS / SDS

Triphenylphosphine

Revision Date:2024-08-24Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: Triphenylphosphine
  • CBnumber: CB8771461
  • CAS: 603-35-0
  • EINECS Number: 210-036-0
  • Synonyms: PPH3,triphenylphosphine

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 400-158-6606

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Symbol(GHS)
  • Signal wordWarning
Precautionary statements
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.
P321 Specific treatment (see … on this label).
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
Hazard statements
H373 May cause damage to organs through prolonged or repeated exposure
H317 May cause an allergic skin reaction
H302 Harmful if swallowed

SECTION 3: Composition/information on ingredients

Substance

  • Product name: Triphenylphosphine
  • Synonyms: PPH3,triphenylphosphine
  • CAS: 603-35-0
  • EC number: 210-036-0
  • MF: C18H15P
  • MW: 262.29

SECTION 4: First aid measures

Description of first aid measures

General advice
Consult a physician. Show this material safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11

Indication of any immediate medical attention and special treatment needed

No data available

SECTION 5: Firefighting measures

Extinguishing media

Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Special hazards arising from the substance or mixture

Carbon oxides Oxides of phosphorus

Advice for firefighters

Wear self-contained breathing apparatus for firefighting if necessary.

Further information

No data available

NFPA 704

2
1
0
HEALTH 2 Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine)
FIRE 1 Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia)
REACT 0 Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)
SPEC. HAZ.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains.

Methods and materials for containment and cleaning up

Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.

Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

Precautions for safe handling

Advice on safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols.

Advice on protection against fire and explosion

Provide appropriate exhaust ventilation at places where dust is formed.

Hygiene measures

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

For precautions see section 2.2.

Conditions for safe storage, including any incompatibilities

Storage conditions

Keep container tightly closed in a dry and well-ventilated place. Store in cool place.

Specific end use(s)

Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

control parameter

Hazard composition and occupational exposure limits
Does not contain substances with occupational exposure limits.

Exposure controls

Personal protective equipment
Eye/face protection

Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.

The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.

Full contact

Material: Nitrile rubber

Minimum layer thickness: 0,11 mm Break through time: 480 min

Material tested:Dermatril? (KCL 740 / Aldrich Z677272, Size M)

Splash contact Material: Nitrile rubber

Minimum layer thickness: 0,11 mm Break through time: 480 min

Material tested:Dermatril? (KCL 740 / Aldrich Z677272, Size M)

data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374

If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the EC approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.

Body Protection

Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection

Where risk assessment shows air-purifying respirators are appropriate use a full- face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Control of environmental exposure

Prevent further leakage or spillage if safe to do so. Do not let product enter drains.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • Appearancewhite crystalline
  • Odourodorless
  • Odour ThresholdNo data available
  • pHNo data available
  • Melting point/freezing pointpoint/range: 79 - 81 °C - lit.
  • Initial boiling point and boiling range377 °C - lit.
  • Flash point180 °C - closed cup
  • Evaporation rateNo data available
  • Flammability (solid, gas)The product is not flammable. - Flammability (solids)
  • Upper/lower flammability or explosive limitsNo data available
  • Vapour pressure< 0,1 hPa at 25 °C - OECD Test Guideline 104
  • Vapour density 9,06 - (Air = 1.0)
  • Relative density1,19 at 25 °C
  • Water solubility0,00017 g/l at 22 °C - Regulation (EC) No. 440/2008, Annex, A.6
  • Partition coefficient: n-octanol/waterNo data available
  • Autoignition temperature 425 °C at 983 hPa - Relative self-ignition temperature for solids
  • Decomposition temperatureNo data available
  • ViscosityViscosity, kinematic: No data available Viscosity, dynamic: No data available
  • Explosive propertiesNo data available
  • Oxidizing propertiesNo data available

Other safety information

Relative vapor density

9,06 - (Air = 1.0)

SECTION 10: Stability and reactivity

Reactivity

No data available

Chemical stability

Stable under recommended storage conditions.

Possibility of hazardous reactions

No data available

Conditions to avoid

No data available

Incompatible materials

Oxidizing agents

Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

Information on toxicological effects

Acute toxicity
LD50 Oral - Rat - 700 mg/kg
Remarks:
(ECHA)
LC50 Inhalation - Rat - male - 4 h - 12,5 mg/l Remarks:
(ECHA)
LD50 Dermal - Rabbit - male and female - > 4.000 mg/kg Remarks:
Limit Test (ECHA)
Skin corrosion/irritation
Skin - Rabbit
Result: No skin irritation - 20 h Remarks:
(ECHA)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Causes serious eye damage. Remarks:
(ECHA)
Respiratory or skin sensitization
(Regulation (EC) No. 440/2008, Annex, B.6)
Germ cell mutagenicity
Ames test
S. typhimurium Result: negative Remarks:
(ECHA)
In vitro mammalian cell gene mutation test Chinese hamster ovary cells
Result: negative
Mutagenicity (mammal cell test): micronucleus. Chinese hamster lung cells
Result: negative Remarks:
(ECHA)
Mouse - male and female - Bone marrow Result: negative
Carcinogenicity
IARC: No ingredient of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
Inhalation - Causes damage to organs through prolonged or repeated exposure. - Central nervous system, Peripheral nervous system
Aspiration hazard
No data available
Toxicity
LD50 orally in Rabbit: 700 mg/kg LD50 dermal Rabbit > 4000 mg/kg

SECTION 12: Ecological information

Toxicity

Toxicity to fish
static test LC50 - Leuciscus idus (Golden orfe) - > 10.000 mg/l - 96 h

(OECD Test Guideline 203)

Toxicity to daphnia and other aquatic invertebrates

static test EC50 - Daphnia magna (Water flea) - > 5 mg/l - 48 h (OECD Test Guideline 202)

Remarks: (above the solubility limit in the test medium)


Toxicity to algae
static test NOEC - Desmodesmus subspicatus (green algae) - > 5 mg/l - 72 h

(OECD Test Guideline 201)

Remarks: (above the solubility limit in the test medium)


static test ErC50 - Desmodesmus subspicatus (green algae) - > 5 mg/l - 72 h

(OECD Test Guideline 201)

Remarks: (above the solubility limit in the test medium)


Toxicity to bacteria
static test EC50 - Pseudomonas putida - > 10.000 mg/l - 0,5 h (DIN 38412)

Persistence and degradability

Biodegradability aerobic - Exposure time 28 d

Result: < 20 % - Not biodegradable. (OECD Test Guideline 301F)

Bioaccumulative potential

No data available

Mobility in soil

No data available

Results of PBT and vPvB assessment

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

Other adverse effects

No data available

SECTION 13: Disposal considerations

Waste treatment methods

Product

Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or

mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Waste material must be disposed of in accordance with the Directive on waste 2008/98/EC as well as other national and local regulations. Leave chemicals in original containers. No mixing with other waste. Handle uncleaned containers like the product itself.

Contaminated packaging

Dispose of as unused product.

SECTION 14: Transport information

UN number

ADR/RID: - IMDG: - IATA: -

UN proper shipping name

ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA: Not dangerous goods

Transport hazard class(es)

ADR/RID: - IMDG: - IATA: -

Packaging group

ADR/RID: - IMDG: - IATA: -

Environmental hazards

ADR/RID: no IMDG Marine pollutant: no IATA: no

Special precautions for user

Further information

Not classified as dangerous in the meaning of transport regulations.

SECTION 15: Regulatory information

Safety, health and environmental regulations/legislation specific for the substance or mixture

Regulations on the Safety Management of Hazardous Chemicals
China Catalog of Hazardous chemicals 2015:Listed. website: https://www.mem.gov.cn/
Measures for Environmental Management of New Chemical Substances
Vietnam National Chemical Inventory:Listed. website: https://chemicaldata.gov.vn/
United States Toxic Substances Control Act (TSCA) Inventory:Listed. website: https://www.epa.gov/
Philippines Inventory of Chemicals and Chemical Substances (PICCS):Listed. website: https://emb.gov.ph/
New Zealand Inventory of Chemicals (NZIoC):Listed. website: https://www.epa.govt.nz/
Korea Existing Chemicals List (KECL):Listed. website: http://ncis.nier.go.kr
European Inventory of Existing Commercial Chemical Substances (EINECS):Listed. website: https://echa.europa.eu/
EC Inventory:Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC):Listed. website: https://www.mee.gov.cn/

SECTION 16: Other information

Abbreviations and acronyms

  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • CAS: Chemical Abstracts Service
  • EC50: Effective Concentration 50%
  • IATA: International Air Transportation Association
  • IMDG: International Maritime Dangerous Goods
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • STEL: Short term exposure limit
  • TWA: Time Weighted Average

References

【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple

【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp

【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/

【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en

【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg

【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp

【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm

【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/

【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home

【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/

Other Information

Isolate contaminated clothing by sealing in a bag or other container.Do NOT take working clothes home.
Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

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