CAFESTOL
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- ₹32341 - ₹54237
- Product name: CAFESTOL
- CAS: 469-83-0
- MF: C20H28O3
- MW: 316.43
- EINECS:
- MDL Number:MFCD01075769
- Synonyms:CAFESTEROL;CAFESTOL;3bα,4,5,6,7,8,9,10,10aα,10b,11,12-Dodecahydro-7β-hydroxy-10bβ-methyl-5aβ,8β-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7α-methanol;5A,8-Methano-5ah-cyclohepta(5,6)naphtho(2,1-B)furan-7-methanol, 3B,4,5,6,7,8,9,10,10A,10B,11,12-dodecahydro-7-hydroxy-10B-methyl-, (3bs-(3balpha,5abeta,7beta,8beta,10aalpha,10bbeta))-;5A,8-Methano-5ah-cyclohepta(5,6)naphtho(2,1-B)furan-7-methanol, 3B,4,5,6,7,8,9,10,10A,10B,11,12-dodecahydro-7-hydroxy-10B-methyl-, (3bs,5as,7R,8R,10ar,10bs)-;Ccris 1518;CAFESTOL(SH);(3bS,5aS,7R,8R,10aR,10bS)-3b,4,5,6,7,8,9,10,10a,10b,11,12-Dodecahydro-7-hydroxy-10b-methyl-5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol
2 prices
Selected condition：
Brand
- ALFA India
Package
- 50mg
- 100mg
- ManufacturerALFA India
- Product numberALF-J65355-MF
- Product descriptionCafestol
- Packaging50mg
- Price₹32341
- Updated2022-05-26
- Buy
- ManufacturerALFA India
- Product numberALF-J65355-MC
- Product descriptionCafestol
- Packaging100mg
- Price₹54237
- Updated2022-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ALFA India | ALF-J65355-MF | Cafestol | 50mg | ₹32341 | 2022-05-26 | Buy |
| ALFA India | ALF-J65355-MC | Cafestol | 100mg | ₹54237 | 2022-05-26 | Buy |
Properties
Melting point :160-162℃ (Decomposition) (ethyl ether pentane )
alpha :D -101°
Boiling point :468.6±45.0 °C(Predicted)
Density :1.23±0.1 g/cm3 (20 ºC 760 Torr)
RTECS :PB9185090
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :Soluble in dichlormethane, DMSO or ethanol
form :White to off-white solid.
pka :14.44±0.40(Predicted)
color :Off-White to Light Beige
optical activity :-9724 (CHCl3)
Major Application :food and beverages
InChI :1S/C20H28O3/c1-18-7-5-16-14(6-9-23-16)15(18)4-8-19-10-13(2-3-17(18)19)20(22,11-19)12-21/h6,9,13,15,17,21-22H,2-5,7-8,10-12H2,1H3/t13-,15-,17+,18-,19+,20+/m1/s1
InChIKey :DNJVYWXIDISQRD-HWUKTEKMSA-N
SMILES :[o]1c2c(cc1)[C@@H]3[C@]([C@H]4[C@]5(C[C@H]([C@@](C5)(O)CO)CC4)CC3)(CC2)C
LogP :4.234 (est)
alpha :D -101°
Boiling point :468.6±45.0 °C(Predicted)
Density :1.23±0.1 g/cm3 (20 ºC 760 Torr)
RTECS :PB9185090
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :Soluble in dichlormethane, DMSO or ethanol
form :White to off-white solid.
pka :14.44±0.40(Predicted)
color :Off-White to Light Beige
optical activity :-9724 (CHCl3)
Major Application :food and beverages
InChI :1S/C20H28O3/c1-18-7-5-16-14(6-9-23-16)15(18)4-8-19-10-13(2-3-17(18)19)20(22,11-19)12-21/h6,9,13,15,17,21-22H,2-5,7-8,10-12H2,1H3/t13-,15-,17+,18-,19+,20+/m1/s1
InChIKey :DNJVYWXIDISQRD-HWUKTEKMSA-N
SMILES :[o]1c2c(cc1)[C@@H]3[C@]([C@H]4[C@]5(C[C@H]([C@@](C5)(O)CO)CC4)CC3)(CC2)C
LogP :4.234 (est)
Safety Information
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Description
Cafestol is a natural diterpene which is abundant in unfiltered coffee. It elevates serum cholesterol and triglycerides in humans, an effect which does not seem to occur in monkeys, hamsters, rats, or gerbils. Dietary cafestol does increase total cholesterol and triglycerides in ApoE3Leiden mice, an effect which is associated with selective activation of farnesoid X receptors and pregnane X receptors. Cafestol (20 μM) also inhibits the proliferation of human umbilical vein endothelial cells and prevents their migration and tube formation on Matrigel?.Related product price
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