Isoalantolactone
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- ₹0
- Product name: Isoalantolactone
- CAS: 470-17-7
- MF: C15H20O2
- MW: 232.32
- EINECS:
- MDL Number:MFCD08689940
- Synonyms:11(13)-dien-12-oicacid,8-beta-hydroxy-eudesma-4(14gamma-lactone ;ISOALANTOACTONE;ISOALANTOLACTONE;ISOHELENIN;(3ar,4as,8ar,9ar)-8a-methyl-3,5-dimethylene-decahydro-naphtho[2,3-b]furan-2-one;methyl-3,5-bis(methylene)-,(3aR,4aS,8aR,9aR)-;Naphtho[2,3-b]furan-2(3H)-one,decahydro-8a-;(3aR)-3aα,4,4aα,5,6,7,8,8a,9,9aα-Decahydro-3,5-bismethylene-8aβ-methylnaphtho[2,3-b]furan-2(3H)-one
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Properties
Melting point :115℃
Boiling point :364.9±42.0 °C(Predicted)
Density :1.07±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 50 mg/ml) or ethanol (30 mg/ml)
form :solid
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChI :InChI=1S/C15H20O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h11-13H,1-2,4-8H2,3H3/t11-,12+,13-,15-/m1/s1
InChIKey :CVUANYCQTOGILD-QVHKTLOISA-N
SMILES :O1C(=O)C(=C)[C@@]2([H])C[C@]3([H])[C@@](C)(C[C@@]12[H])CCCC3=C
LogP :3.420
CAS DataBase Reference :470-17-7(CAS DataBase Reference)
NIST Chemistry Reference :Naphtho(2,3-b)furan-2(3h)-one, decahydro-8a-methyl-3,5-bis(methylene)-, (3ar-(3a«alpha»,4a«alpha»,8a«beta»,9a«alpha»))-(470-17-7)
Boiling point :364.9±42.0 °C(Predicted)
Density :1.07±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 50 mg/ml) or ethanol (30 mg/ml)
form :solid
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChI :InChI=1S/C15H20O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h11-13H,1-2,4-8H2,3H3/t11-,12+,13-,15-/m1/s1
InChIKey :CVUANYCQTOGILD-QVHKTLOISA-N
SMILES :O1C(=O)C(=C)[C@@]2([H])C[C@]3([H])[C@@](C)(C[C@@]12[H])CCCC3=C
LogP :3.420
CAS DataBase Reference :470-17-7(CAS DataBase Reference)
NIST Chemistry Reference :Naphtho(2,3-b)furan-2(3h)-one, decahydro-8a-methyl-3,5-bis(methylene)-, (3ar-(3a«alpha»,4a«alpha»,8a«beta»,9a«alpha»))-(470-17-7)
Safety Information
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Description
Isohelenin (470-17-7) is a sesquiterpene lactone isolated from Mexican Indian medicinal plants known to have anti-inflammatory properties. A potent inhibitor of NFkB (complete inhibition at 5 μM)1 acting via inhibition of IKK?6. Isohelenin-mediated NFkB inhibition suppresses IL-8 expression2, iNOS expression3 and RANTES biosynthesis4. Displays protective effects in endotoxic shock in rodent models.5 Induces apoptosis in glioma cells.6More related product prices
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Suppliers and manufacturers
GK Chemicals
A.J Chemicals
Chengdu GLP biotechnology Co Ltd
Jiangsu Yongjian Pharmaceutical Co.,Ltd
Hubei Danding Pharmaceutical Technology Co., Ltd
Chengdu Biopurify Phytochemicals Ltd.
CONIER CHEM AND PHARMA LIMITED
Neostar United (Changzhou) Industrial Co., Ltd.
