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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Heterocyclic compound >Pyridine compound >Pyridine derivatives >TPEN

TPEN

TPEN Structure
  • ₹4115 - ₹28760
  • Product name: TPEN
  • CAS: 16858-02-9
  • MF: C26H28N6
  • MW: 424.54
  • EINECS:
  • MDL Number:MFCD00036918
  • Synonyms:TETRAKIS-(2-PYRIDYLMETHYL)ETHYLENEDIAMINE;N,N,N',N'-tetrakis(2-pyridinylmethyl)-1,2-Ethanediamine;TPEN;1,2-Ethanediamine, N,N,N',N'-tetrakis(2-pyridinylmethyl)-;1,2-Ethanediamine, N,N,N',N'-tetrakis(2-pyridinylmethyl)-, (oc-6-11)-;N1,N1,N2,N2-tetrakis(pyridin-2-ylMethyl)ethane-1,2-diaMine;N,N,N',N'-Tetrakis(2-pyridylmethyl)ethylenediamine;N,N,N',N',-TETRAKIS(2-PYRIDYLMETHYL)*ETH YLENEDIAMIN
Price6 Properties Safety Information Description
6 prices
Selected condition：

Brand

  • ALFA India
  • Sigma-Aldrich(India)
  • TCI Chemicals (India)

Package

  • 50MG
  • 100mg
  • 300mg
  • 1G
  • 5G
  • ManufacturerALFA India
  • Product numberALF-J64206-MC
  • Product descriptionN,N,N',N'-Tetrakis-(2-pyridylmethyl)ethylenediamine
  • Packaging100mg
  • Price₹4115
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP4413
  • Product descriptionN,N,N′,N′-Tetrakis(2-pyridylmethyl)ethylenediamine
  • Packaging50MG
  • Price₹10251.28
  • Updated2022-06-14
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberT1487
  • Product descriptionN,N,N',N'-Tetrakis(2-pyridylmethyl)ethylenediamine
  • Packaging1G
  • Price₹10800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP4413
  • Product descriptionN,N,N′,N′-Tetrakis(2-pyridylmethyl)ethylenediamine
  • Packaging100MG
  • Price₹17049.38
  • Updated2022-06-14
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberT1487
  • Product descriptionN,N,N',N'-Tetrakis(2-pyridylmethyl)ethylenediamine
  • Packaging5G
  • Price₹19500
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-J64206-EXH
  • Product descriptionN,N,N',N'-Tetrakis-(2-pyridylmethyl)ethylenediamine
  • Packaging300mg
  • Price₹28760
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ALFA India ALF-J64206-MC N,N,N',N'-Tetrakis-(2-pyridylmethyl)ethylenediamine 100mg ₹4115 2022-05-26 Buy
Sigma-Aldrich(India) P4413 N,N,N′,N′-Tetrakis(2-pyridylmethyl)ethylenediamine 50MG ₹10251.28 2022-06-14 Buy
TCI Chemicals (India) T1487 N,N,N',N'-Tetrakis(2-pyridylmethyl)ethylenediamine 1G ₹10800 2022-05-26 Buy
Sigma-Aldrich(India) P4413 N,N,N′,N′-Tetrakis(2-pyridylmethyl)ethylenediamine 100MG ₹17049.38 2022-06-14 Buy
TCI Chemicals (India) T1487 N,N,N',N'-Tetrakis(2-pyridylmethyl)ethylenediamine 5G ₹19500 2022-05-26 Buy
ALFA India ALF-J64206-EXH N,N,N',N'-Tetrakis-(2-pyridylmethyl)ethylenediamine 300mg ₹28760 2022-05-26 Buy

Properties

Melting point :110-112 °C
Boiling point :530.56°C (rough estimate)
Density :1.3893 (rough estimate)
refractive index :1.4570 (estimate)
storage temp. :Sealed in dry,2-8°C
solubility :Soluble in DMSO (up to 10 mg/ml).
pka :5.19±0.12(Predicted)
form :Tan solid
color :Off-white or tan
BRN :4211982
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C26H28N6/c1-5-13-27-23(9-1)19-31(20-24-10-2-6-14-28-24)17-18-32(21-25-11-3-7-15-29-25)22-26-12-4-8-16-30-26/h1-16H,17-22H2
InChIKey :CVRXLMUYFMERMJ-UHFFFAOYSA-N
SMILES :C(N(CC1=NC=CC=C1)CC1=NC=CC=C1)CN(CC1=NC=CC=C1)CC1=NC=CC=C1
CAS DataBase Reference :16858-02-9(CAS DataBase Reference)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

As a cofactor of more than 300 enzymes, zinc is integral for a wide variety of cellular processes that affect most biological functions. Most notably, its bioavailability is important to the regulation of apoptosis, cell proliferation, and differentiation. TPEN is a cell permeant metal ion chelator that is used in zinc treatment studies to limit intra- and extracellular concentrations of the mineral. At a concentration as low as 6 μM, TPEN-induced zinc depletion decreases X-linked inhibitor of apoptosis (XIAP) levels in human PC-3 prostate cancer cells and promotes caspase-3 and -9 activation. At 25 μM, TPEN attenuates hypoxic pulmonary vasoconstriction in rodent isolated perfused lung.

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Suppliers and manufacturers

career henan chemical co
TPEN
₹1.00 /1KG
TPEN CAS:16858-02-9
A.J Chemicals CLEARSYNTH LABS LTD. CHEMSWORTH TCI Chemicals (India) Pvt. Ltd. Alfa Aesar
Capot Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
Zhengzhou Alfa Chemical Co.,Ltd