2-(4-(5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-ylamino)ethanolhydrochloride
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- $45 - $2600
- Product name: 2-(4-(5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-ylamino)ethanolhydrochloride
- CAS: 1094042-01-9
- MF: C23H27N3O4
- MW: 409.48
- EINECS:
- MDL Number:MFCD12912402
- Synonyms:2-(4-(5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-ylamino)ethanolhydrochloride;CYM 5442 hydrochloride;CYM 5442;2-(4-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-ylamino)ethanol;CYM5442 , 1094042-01-9;Ethanol, 2-[[4-[5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl]amino]-;CYM 5442 HCl;CYM 5442;CYM-5442
24 prices
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Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 5mg
- 1mg
- 50
- 10MG
- 25mg
- 50MG
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number2809DC
- Product description2-({4-[5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl}amino)ethan-1-ol
- Packaging5mg
- Price$257
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2809DC
- Product description2-({4-[5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl}amino)ethan-1-ol
- Packaging25mg
- Price$665
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberLIP0000532
- Product descriptionCYM-5442 95.00%
- Packaging10MG
- Price$745.85
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberLIP0000532
- Product descriptionCYM-5442 95.00%
- Packaging50MG
- Price$1417.71
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7441
- Product descriptionCYM5442hydrochloride
- Packaging5mg
- Price$162
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7441
- Product descriptionCYM5442hydrochloride
- Packaging10mg
- Price$258
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7441
- Product descriptionCYM5442hydrochloride
- Packaging25mg
- Price$581
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16925
- Product descriptionCYM 5442 ≥95%
- Packaging1mg
- Price$49
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16925
- Product descriptionCYM 5442 ≥95%
- Packaging5mg
- Price$143
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16925
- Product descriptionCYM 5442 ≥95%
- Packaging10mg
- Price$229
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16925
- Product descriptionCYM 5442 ≥95%
- Packaging25mg
- Price$509
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0002981
- Product descriptionCYM5442 ≥98.0%
- Packaging5mg
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0002981
- Product descriptionCYM5442 ≥98.0%
- Packaging10mg
- Price$360
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004599
- Product descriptionCYM5442 95+%
- Packaging100mg
- Price$285
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004599
- Product descriptionCYM5442 95+%
- Packaging1g
- Price$1140
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8088
- Product descriptionCYM5442 >98%
- Packaging250mg
- Price$1300
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2809DC | 2-({4-[5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl}amino)ethan-1-ol | 5mg | $257 | 2021-12-16 | Buy |
| AK Scientific | 2809DC | 2-({4-[5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl}amino)ethan-1-ol | 25mg | $665 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | LIP0000532 | CYM-5442 95.00% | 10MG | $745.85 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | LIP0000532 | CYM-5442 95.00% | 50MG | $1417.71 | 2021-12-16 | Buy |
| ApexBio Technology | B7441 | CYM5442hydrochloride | 5mg | $162 | 2021-12-16 | Buy |
| ApexBio Technology | B7441 | CYM5442hydrochloride | 10mg | $258 | 2021-12-16 | Buy |
| ApexBio Technology | B7441 | CYM5442hydrochloride | 25mg | $581 | 2021-12-16 | Buy |
| Cayman Chemical | 16925 | CYM 5442 ≥95% | 1mg | $49 | 2024-03-01 | Buy |
| Cayman Chemical | 16925 | CYM 5442 ≥95% | 5mg | $143 | 2024-03-01 | Buy |
| Cayman Chemical | 16925 | CYM 5442 ≥95% | 10mg | $229 | 2024-03-01 | Buy |
| Cayman Chemical | 16925 | CYM 5442 ≥95% | 25mg | $509 | 2024-03-01 | Buy |
| ChemScene | CS-0002981 | CYM5442 ≥98.0% | 5mg | $220 | 2021-12-16 | Buy |
| ChemScene | CS-0002981 | CYM5442 ≥98.0% | 10mg | $360 | 2021-12-16 | Buy |
| Crysdot | CD31004599 | CYM5442 95+% | 100mg | $285 | 2021-12-16 | Buy |
| Crysdot | CD31004599 | CYM5442 95+% | 1g | $1140 | 2021-12-16 | Buy |
| DC Chemicals | DC8088 | CYM5442 >98% | 250mg | $1300 | 2021-12-16 | Buy |
Properties
Boiling point :617.5±65.0 °C(Predicted)
Density :1.27±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: >5mg/mL
form :A crystalline solid
pka :14.73±0.10(Predicted)
Density :1.27±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: >5mg/mL
form :A crystalline solid
pka :14.73±0.10(Predicted)
Safety Information
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Description
Sphingosine-1-phosphate (S1P) is an extracellular lipid mediator whose major effects are mediated through five distinct G protein-coupled receptors, S1P1/EDG-1, S1P2/EDG-5, S1P3/EDG-3, S1P4/EDG-6, and S1P5/EDG-8. S1P1 is important for vascular development and lymphocyte maturation, migration, and trafficking. CYM 5442 is a full agonist for S1P1 internalization, phosphorylation, and ubiquitination (EC50 = 1.35 nM). It is ineffective at S1P2, S1P3, S1P4, and S1P5 at concentrations up to 10 μM. CYM 5442 has been found to activate S1P1-mediated p42/p44 MAPK phosphorylation in CHO-K1 cells transfected with S1P1 with an EC50 value of 46 nM. At 50 nM, CYM 5442 can induce S1P1-dependent lymphopenia in mice, decreasing B and T cells by 65 and 85%, respectively.Related product price
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