4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline
![4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline price.](/CAS/GIF/1206711-16-1.gif)
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- $38 - $1900
- Product name: 4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline
- CAS: 1206711-16-1
- MF: C24H20N4O
- MW: 380.44
- EINECS:
- MDL Number:MFCD18384963
- Synonyms:4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline;Quinoline, 4-[6-[4-(1-methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-;4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline DMH 1;DMH 1 4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline;4-[6-(4-Isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline;DMH-1, >=98%;4-[6-(4-propan-2-yloxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline;DMH-1(VU036482)
34 prices
Selected condition：
Brand
- Ambeed
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 50
- 10
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 10mM(in 1mL DMSO)
- ManufacturerAmbeed
- Product numberA590459
- Product descriptionDMH-1 99+%
- Packaging5mg
- Price$89
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA590459
- Product descriptionDMH-1 99+%
- Packaging10mg
- Price$115
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA590459
- Product descriptionDMH-1 99+%
- Packaging25mg
- Price$195
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA590459
- Product descriptionDMH-1 99+%
- Packaging50mg
- Price$256
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA590459
- Product descriptionDMH-1 99+%
- Packaging100mg
- Price$465
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA590459
- Product descriptionDMH-1 99+%
- Packaging250mg
- Price$686
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA590459
- Product descriptionDMH-1 99+%
- Packaging1g
- Price$1732
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3686
- Product descriptionDMH-1
- Packaging10mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3686
- Product descriptionDMH-1
- Packaging10mM(in 1mL DMSO)
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3686
- Product descriptionDMH-1
- Packaging25mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3686
- Product descriptionDMH-1
- Packaging50mg
- Price$240
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBD162772
- Product descriptionDMH 1
- Packaging10mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBD162772
- Product descriptionDMH 1
- Packaging50mg
- Price$472.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16679
- Product descriptionDMH1 ≥98%
- Packaging1mg
- Price$38
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16679
- Product descriptionDMH1 ≥98%
- Packaging5mg
- Price$96
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16679
- Product descriptionDMH1 ≥98%
- Packaging10mg
- Price$130
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Ambeed | A590459 | DMH-1 99+% | 5mg | $89 | 2021-12-16 | Buy |
| Ambeed | A590459 | DMH-1 99+% | 10mg | $115 | 2021-12-16 | Buy |
| Ambeed | A590459 | DMH-1 99+% | 25mg | $195 | 2021-12-16 | Buy |
| Ambeed | A590459 | DMH-1 99+% | 50mg | $256 | 2021-12-16 | Buy |
| Ambeed | A590459 | DMH-1 99+% | 100mg | $465 | 2021-12-16 | Buy |
| Ambeed | A590459 | DMH-1 99+% | 250mg | $686 | 2021-12-16 | Buy |
| Ambeed | A590459 | DMH-1 99+% | 1g | $1732 | 2021-12-16 | Buy |
| ApexBio Technology | B3686 | DMH-1 | 10mg | $80 | 2021-12-16 | Buy |
| ApexBio Technology | B3686 | DMH-1 | 10mM(in 1mL DMSO) | $90 | 2021-12-16 | Buy |
| ApexBio Technology | B3686 | DMH-1 | 25mg | $160 | 2021-12-16 | Buy |
| ApexBio Technology | B3686 | DMH-1 | 50mg | $240 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BD162772 | DMH 1 | 10mg | $135 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BD162772 | DMH 1 | 50mg | $472.5 | 2021-12-16 | Buy |
| Cayman Chemical | 16679 | DMH1 ≥98% | 1mg | $38 | 2024-03-01 | Buy |
| Cayman Chemical | 16679 | DMH1 ≥98% | 5mg | $96 | 2024-03-01 | Buy |
| Cayman Chemical | 16679 | DMH1 ≥98% | 10mg | $130 | 2024-03-01 | Buy |
Properties
Melting point :178 °C
Density :1.24±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
pka :3.34±0.46(Predicted)
form :powder
color :light yellow to orange
Density :1.24±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
pka :3.34±0.46(Predicted)
form :powder
color :light yellow to orange
Safety Information
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Description
Bone morphogenetic proteins (BMP) are secreted signaling proteins, many of which are involved in various developmental processes, in addition to bone formation. DMH1 is an analog of the non-selective BMP receptor inhibitor dorsomorphin that potently inhibits the kinase activity of activin receptor-like kinase 2 (ALK2; IC50 = 13-108 nM). It is much less effective at ALK4, ALK5, AMPK, KDR (VEGFR2) or PDGFRβ, although it inhibits ALK1 and ALK3 at nanomolar concentrations. DMH1 is effective in vivo, as it disrupts dorsoventral development in zebrafish. It also affects stem cell development, increasing cardiomyocyte progenitors and promoting neurogenesis. DMH1 inhibits the growth of lung cancer cells, reducing tumor growth in a xenograft mouse model.More related product prices
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Suppliers and manufacturers
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![4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline](https://img.chemicalbook.com/ProductImageEN/2019-12/small/9f6db54e-092a-41d9-ab18-d369af1d6993.png){kind=small}