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ChemicalBook >> CAS DataBase List >> Y27632 (hydrochloride)

Y27632 (hydrochloride)

Y27632 (hydrochloride) price.
  • $32 - $2650
  • Product name: Y27632 (hydrochloride)
  • CAS: 129830-38-2
  • MF: C14H23Cl2N3O
  • MW: 320.25792
  • EINECS:813-428-5
  • MDL Number:MFCD03490488
  • Synonyms:(R)-4-(1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride;Y-27632 DIHYDROCHLORIDE;ROCK INHIBITOR;Y-27632 dihydrochloride, >=98%;trans-4-[(R)-1-Aminoethyl]-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride Y 27632 dihydrochloride;Y 27632 dihydrochloride (+)-trans-N-(4-Pyridyl)-4-[(R)-1-aminoethyl]cyclohexanecarboxamide dihydrochloride;Y27632 (hydrochloride);(+)-trans-N-(4-Pyridyl)-4-[(R)-1-aminoethyl]cyclohexanecarboxamide dihydrochloride;trans-4-[(R)-1-Aminoethyl]-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride
Price51 Properties Safety Information Description
51 prices
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Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Arctom
  • Ark Pharm
  • Axon Medchem
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
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  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3564-M001
  • Product descriptionY 27632 Dihydrochloride ≥98%(HPLC)Containsapprox.1.4%water.
  • Packaging1mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberX7611
  • Product descriptionY 27632 Dihydrochloride
  • Packaging1mg
  • Price$99
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberX7611
  • Product descriptionY 27632 Dihydrochloride
  • Packaging50mg
  • Price$274
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA101744
  • Product descriptiontrans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamidedihydrochloride 99+%
  • Packaging5mg
  • Price$32
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA101744
  • Product descriptiontrans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamidedihydrochloride 99+%
  • Packaging1mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA101744
  • Product descriptiontrans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamidedihydrochloride 99+%
  • Packaging25mg
  • Price$54
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA101744
  • Product descriptiontrans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamidedihydrochloride 99+%
  • Packaging10mg
  • Price$54
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA101744
  • Product descriptiontrans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamidedihydrochloride 99+%
  • Packaging50mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA101744
  • Product descriptiontrans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamidedihydrochloride 99+%
  • Packaging100mg
  • Price$79
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA101744
  • Product descriptiontrans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamidedihydrochloride 99+%
  • Packaging1g
  • Price$362
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA101744
  • Product descriptiontrans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamidedihydrochloride 99+%
  • Packaging250mg
  • Price$362
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000327
  • Product descriptionY-27632 DIHYDROCHLORIDE 95.00%
  • Packaging1MG
  • Price$634.27
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS022712
  • Product descriptiontrans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamidedihydrochloride ≥99%
  • Packaging1mg
  • Price$32
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS022712
  • Product descriptiontrans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamidedihydrochloride ≥99%
  • Packaging5mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS022712
  • Product descriptiontrans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamidedihydrochloride ≥99%
  • Packaging10mg
  • Price$53
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS022712
  • Product descriptiontrans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamidedihydrochloride ≥99%
  • Packaging25mg
  • Price$64
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-3564-M001 Y 27632 Dihydrochloride ≥98%(HPLC)Containsapprox.1.4%water. 1mg $45 2021-12-16 Buy
AK Scientific X7611 Y 27632 Dihydrochloride 1mg $99 2021-12-16 Buy
AK Scientific X7611 Y 27632 Dihydrochloride 50mg $274 2021-12-16 Buy
Ambeed A101744 trans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamidedihydrochloride 99+% 5mg $32 2021-12-16 Buy
Ambeed A101744 trans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamidedihydrochloride 99+% 1mg $39 2021-12-16 Buy
Ambeed A101744 trans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamidedihydrochloride 99+% 25mg $54 2021-12-16 Buy
Ambeed A101744 trans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamidedihydrochloride 99+% 10mg $54 2021-12-16 Buy
Ambeed A101744 trans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamidedihydrochloride 99+% 50mg $65 2021-12-16 Buy
Ambeed A101744 trans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamidedihydrochloride 99+% 100mg $79 2021-12-16 Buy
Ambeed A101744 trans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamidedihydrochloride 99+% 1g $362 2021-12-16 Buy
Ambeed A101744 trans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamidedihydrochloride 99+% 250mg $362 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000327 Y-27632 DIHYDROCHLORIDE 95.00% 1MG $634.27 2021-12-16 Buy
Arctom AS022712 trans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamidedihydrochloride ≥99% 1mg $32 2021-12-16 Buy
Arctom AS022712 trans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamidedihydrochloride ≥99% 5mg $39 2021-12-16 Buy
Arctom AS022712 trans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamidedihydrochloride ≥99% 10mg $53 2021-12-16 Buy
Arctom AS022712 trans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamidedihydrochloride ≥99% 25mg $64 2021-12-16 Buy
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Properties

Melting point :258℃
storage temp. :2-8°C
solubility :H2O: soluble14mg/mL
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or methanol may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Y-27632 dihydrochloride is a selective Rho-kinase inhibitor, which suppresses cholinergic nerve-mediated contractions. In addition, studies show that Y-27632 dihydrochloride increases the release of neurotransmitters from cholinergic nerves. Studies conducted on smooth muscle preparations suggest that Y-27632 dihydrochloride suppresses nerve-mediated contractile responses stimulated by acetylcholine and noradrenaline. Furthermore, studies on lung tissue damage in rats suggest that Y-27632 dihydrochloride can restore the damage caused by oleic acid by inhibition of ROCK-1 and ROCK-2. Y-27632 dihydrochloride also inhibits protein kinase C related kinase, PRK2.

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