5-(4-aMino-1-isopropyl-1H-pyrazolo[3,4-d]pyriMidin-3-yl)benzo[d]oxazol-2-aMine
![5-(4-aMino-1-isopropyl-1H-pyrazolo[3,4-d]pyriMidin-3-yl)benzo[d]oxazol-2-aMine price.](/CAS/GIF/1224844-38-5.gif)
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- $31 - $4620
- Product name: 5-(4-aMino-1-isopropyl-1H-pyrazolo[3,4-d]pyriMidin-3-yl)benzo[d]oxazol-2-aMine
- CAS: 1224844-38-5
- MF: C15H15N7O
- MW: 309.33
- EINECS:
- MDL Number:MFCD22124893
- Synonyms:5-(4-aMino-1-isopropyl-1H-pyrazolo[3,4-d]pyriMidin-3-yl)benzo[d]oxazol-2-aMine;3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine;INK-128;3-(2-aminobenzo[d]oxazol-5-yl)-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine;INK-128 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine;MLN0128;5-(4-amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzoxazol-2-amine;-(4-aMino-1-isopropyl-1H-pyrazolo[3,4-d]pyriMidin-3-yl)benzo[d]oxazol-2-aMine
45 prices
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Brand
- Acrotein
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- TRC
Package
- 5MG
- 10mM(in 1mL DMSO)
- 1MG
- 10mg
- 25mg
- 50mg
- 0.1g
- 100mg
- 200mg
- 0.25g
- 250mg
- 500mg
- 1g
- 1000mg
- 2g
- ManufacturerAcrotein
- Product numberUT00151
- Product description5-(4-Amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzoxazol-2-amine 97%
- Packaging0.1g
- Price$183.33
- Updated2021-12-16
- Buy
- ManufacturerAcrotein
- Product numberUT00151
- Product description5-(4-Amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzoxazol-2-amine 97%
- Packaging0.25g
- Price$383.33
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1157-M010
- Product descriptionMLN0128 ≥95%
- Packaging10mg
- Price$281
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2477AH
- Product description3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
- Packaging100mg
- Price$211
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2477AH
- Product description3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
- Packaging250mg
- Price$329
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2477AH
- Product description3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
- Packaging1g
- Price$784
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0013722
- Product description3-(2-AMINO-5-BENZOXAZOLYL)-1-(1-METHYLETHYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE 95.00%
- Packaging1MG
- Price$222.6
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0013722
- Product description3-(2-AMINO-5-BENZOXAZOLYL)-1-(1-METHYLETHYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE 95.00%
- Packaging5MG
- Price$500.81
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8551
- Product descriptionINK128(MLN0128)
- Packaging5mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8551
- Product descriptionINK128(MLN0128)
- Packaging10mM(in 1mL DMSO)
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8551
- Product descriptionINK128(MLN0128)
- Packaging10mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60099
- Product descriptionSapanisertib(MLN0128)
- Packaging10mg
- Price$238
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2142
- Product descriptionINK128 99%
- Packaging5mg
- Price$121
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546175
- Product descriptionINK-128 >98%
- Packaging5mg
- Price$147.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546175
- Product descriptionINK-128 >98%
- Packaging25mg
- Price$241.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181035
- Product descriptionINK-128 >98%
- Packaging100mg
- Price$690.2
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Acrotein | UT00151 | 5-(4-Amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzoxazol-2-amine 97% | 0.1g | $183.33 | 2021-12-16 | Buy |
| Acrotein | UT00151 | 5-(4-Amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzoxazol-2-amine 97% | 0.25g | $383.33 | 2021-12-16 | Buy |
| Adipogen Life Sciences | SYN-1157-M010 | MLN0128 ≥95% | 10mg | $281 | 2021-12-16 | Buy |
| AK Scientific | 2477AH | 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | 100mg | $211 | 2021-12-16 | Buy |
| AK Scientific | 2477AH | 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | 250mg | $329 | 2021-12-16 | Buy |
| AK Scientific | 2477AH | 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | 1g | $784 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0013722 | 3-(2-AMINO-5-BENZOXAZOLYL)-1-(1-METHYLETHYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE 95.00% | 1MG | $222.6 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0013722 | 3-(2-AMINO-5-BENZOXAZOLYL)-1-(1-METHYLETHYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE 95.00% | 5MG | $500.81 | 2021-12-16 | Buy |
| ApexBio Technology | A8551 | INK128(MLN0128) | 5mg | $80 | 2021-12-16 | Buy |
| ApexBio Technology | A8551 | INK128(MLN0128) | 10mM(in 1mL DMSO) | $90 | 2021-12-16 | Buy |
| ApexBio Technology | A8551 | INK128(MLN0128) | 10mg | $100 | 2021-12-16 | Buy |
| Arctom | CFN60099 | Sapanisertib(MLN0128) | 10mg | $238 | 2021-12-16 | Buy |
| Axon Medchem | Axon2142 | INK128 99% | 5mg | $121 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546175 | INK-128 >98% | 5mg | $147.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546175 | INK-128 >98% | 25mg | $241.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181035 | INK-128 >98% | 100mg | $690.2 | 2021-12-16 | Buy |
Properties
Melting point :270-272°C (dec.)
Boiling point :598.8±60.0 °C(Predicted)
Density :1.64
storage temp. :-20°C
solubility :Soluble in DMSO (up to 25 mg/ml)
pka :3.77±0.30(Predicted)
form :solid
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Boiling point :598.8±60.0 °C(Predicted)
Density :1.64
storage temp. :-20°C
solubility :Soluble in DMSO (up to 25 mg/ml)
pka :3.77±0.30(Predicted)
form :solid
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Description
The mammalian target of rapamycin (mTOR) is a kinase which acts as part of two distinct complexes, TORC1 and TORC2. Both complexes (TORC1/2) play central roles in cell growth, gene expression, angiogenesis, and cell survival. INK128 is an inhibitor of TORC1/2, acting as a sub-nanomolar ATP-dependent inhibitor of mTOR kinase. It blocks the phosphorylation of downstream substrates of both TORC1 and TORC2. INK128 interferes with the growth of cell lines which are resistant to rapamycin and pan-PI3K inhibitors. Moreover, daily, oral administration of INK128 inhibits angiogenesis and tumor growth in several xenograft models. The effects of INK128 on gene expression also reduce invasion and metastasis.More related product prices
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Suppliers and manufacturers
career henan chemical co
![5-(4-aMino-1-isopropyl-1H-pyrazolo[3,4-d]pyriMidin-3-yl)benzo[d]oxazol-2-aMine](https://img.chemicalbook.com/ProductImageEN/2018-12/small/fe498182-1055-4d7c-bbd5-8bbb37f80631.png)
ATK CHEMICAL COMPANY LIMITED
Hubei Jusheng Technology Co.,Ltd.
BOC Sciences
Chongqing Chemdad Co., Ltd
CONIER CHEM AND PHARMA LIMITED
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd
TargetMol Chemicals Inc.
HANGZHOU CLAP TECHNOLOGY CO.,LTD
$2.00 /1kg
5-(4-aMino-1-isopropyl-1H-pyrazolo[3,4-d]pyriMidin-3-yl)benzo[d]oxazol-2-aMine CAS:1224844-38-5
5-(4-aMino-1-isopropyl-1H-pyrazolo[3,4-d]pyriMidin-3-yl)benzo[d]oxazol-2-aMine CAS:1224844-38-5