FMOC-O-tert-Butyl-L-serine
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- $6 - $2360
- Product name: FMOC-O-tert-Butyl-L-serine
- CAS: 71989-33-8
- MF: C22H25NO5
- MW: 383.44
- EINECS:276-260-6
- MDL Number:MFCD00037127
- Synonyms:O-tert-Butyl-N-Fmoc-L-serine;9-fluorenylmethoxycarbonyl-O-tert-butyl-L-serine;N-Fmoc-O-tert-Butyl-L-serine, Fmoc-O-tert-butyl-L-serine;N-FMOC-L-Ser (O-tert-Bu) OH;2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-[(2-methylpropan-2-yl)oxy]propanoic acid;N-(9H-Fluorene-9-ylmethoxycarbonyl)-O-tert-butyl-L-serine;N-(9H-Fluorene-9-ylmethoxycarbonyl)-O-tert-butylserine;N-Fmoc-O-tert-Butylserine
60 prices
Selected condition：
Brand
- Acrotein
- Activate Scientific
- AHH
- AK Scientific
- Alfa Aesar
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- BLDpharm
- Chemenu
- Chem-Impex
- ChemPep
- ChemScene
- Crysdot
- Frontier Specialty Chemicals
- Iris Biotech GmbH
- Medical Isotopes, Inc.
- Oakwood
- Sigma-Aldrich
- SynQuest Laboratories
- TCI Chemical
- TRC
Package
- 0.1g
- 1g
- 5G
- 10g
- 25g
- 100g
- 250g
- 500g
- 1kg
- 1000g
- 1mmol
- 20mmol
- ManufacturerAcrotein
- Product numberNA-0556
- Product descriptionN-Fmoc-O-tert-butyl-L-serine 97%
- Packaging250g
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerActivate Scientific
- Product numberAS91745
- Product descriptionFmoc-O-(tert-butyl)-L-serine 95+% ee
- Packaging5G
- Price$20
- Updated2021-12-16
- Buy
- ManufacturerActivate Scientific
- Product numberAS91745
- Product descriptionFmoc-O-(tert-butyl)-L-serine 95+% ee
- Packaging25g
- Price$53
- Updated2021-12-16
- Buy
- ManufacturerActivate Scientific
- Product numberAS91745
- Product descriptionFmoc-O-(tert-butyl)-L-serine 95+% ee
- Packaging100g
- Price$155
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberMT-13943
- Product descriptionFmoc-Ser(t-Bu)-OH 98%
- Packaging100g
- Price$398
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ95887
- Product descriptionFmoc-Ser(tBu)-OH
- Packaging25g
- Price$35
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberK220
- Product descriptionFmoc-Ser(tBu)-OH
- Packaging100g
- Price$147
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberH59422
- Product descriptionN-Fmoc-O-tert-butyl-L-serine, 98%
- Packaging5g
- Price$43.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberH59422
- Product descriptionN-Fmoc-O-tert-butyl-L-serine, 98%
- Packaging25g
- Price$146.65
- Updated2024-03-01
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAAA0001647
- Product descriptionN-FMOC-SER(TERT-BU)-OH 95.00%
- Packaging5G
- Price$850.02
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAAA0001647
- Product descriptionN-FMOC-SER(TERT-BU)-OH 95.00%
- Packaging25G
- Price$1290
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA7960
- Product descriptionFmoc-Ser(tBu)-OH
- Packaging25g
- Price$38
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA7960
- Product descriptionFmoc-Ser(tBu)-OH
- Packaging100g
- Price$115
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS011888
- Product descriptionFmoc-Ser(tBu)-OH 98%
- Packaging5g
- Price$7
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS011888
- Product descriptionFmoc-Ser(tBu)-OH 98%
- Packaging10g
- Price$9
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS011888
- Product descriptionFmoc-Ser(tBu)-OH 98%
- Packaging25g
- Price$19
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Acrotein | NA-0556 | N-Fmoc-O-tert-butyl-L-serine 97% | 250g | $220 | 2021-12-16 | Buy |
| Activate Scientific | AS91745 | Fmoc-O-(tert-butyl)-L-serine 95+% ee | 5G | $20 | 2021-12-16 | Buy |
| Activate Scientific | AS91745 | Fmoc-O-(tert-butyl)-L-serine 95+% ee | 25g | $53 | 2021-12-16 | Buy |
| Activate Scientific | AS91745 | Fmoc-O-(tert-butyl)-L-serine 95+% ee | 100g | $155 | 2021-12-16 | Buy |
| AHH | MT-13943 | Fmoc-Ser(t-Bu)-OH 98% | 100g | $398 | 2021-12-16 | Buy |
| AK Scientific | J95887 | Fmoc-Ser(tBu)-OH | 25g | $35 | 2021-12-16 | Buy |
| AK Scientific | K220 | Fmoc-Ser(tBu)-OH | 100g | $147 | 2021-12-16 | Buy |
| Alfa Aesar | H59422 | N-Fmoc-O-tert-butyl-L-serine, 98% | 5g | $43.65 | 2024-03-01 | Buy |
| Alfa Aesar | H59422 | N-Fmoc-O-tert-butyl-L-serine, 98% | 25g | $146.65 | 2024-03-01 | Buy |
| American Custom Chemicals Corporation | AAA0001647 | N-FMOC-SER(TERT-BU)-OH 95.00% | 5G | $850.02 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | AAA0001647 | N-FMOC-SER(TERT-BU)-OH 95.00% | 25G | $1290 | 2021-12-16 | Buy |
| ApexBio Technology | A7960 | Fmoc-Ser(tBu)-OH | 25g | $38 | 2021-12-16 | Buy |
| ApexBio Technology | A7960 | Fmoc-Ser(tBu)-OH | 100g | $115 | 2021-12-16 | Buy |
| Arctom | AS011888 | Fmoc-Ser(tBu)-OH 98% | 5g | $7 | 2021-12-16 | Buy |
| Arctom | AS011888 | Fmoc-Ser(tBu)-OH 98% | 10g | $9 | 2021-12-16 | Buy |
| Arctom | AS011888 | Fmoc-Ser(tBu)-OH 98% | 25g | $19 | 2021-12-16 | Buy |
Properties
Melting point :130.5-135.5 °C(lit.)
alpha :25 º (c=1,EtOAc 24 ºC)
Boiling point :510.36°C (rough estimate)
Density :1.2369 (rough estimate)
refractive index :24 ° (C=1, AcOEt)
storage temp. :2-8°C
solubility :Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form :powder to crystal
pka :3.44±0.10(Predicted)
color :White to Almost white
optical activity :[α]20/D +25.5±1°, c = 1% in ethyl acetate
BRN :3632013
InChI :InChI=1S/C22H25NO5/c1-22(2,3)28-13-19(20(24)25)23-21(26)27-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,23,26)(H,24,25)/t19-/m0/s1
InChIKey :REITVGIIZHFVGU-IBGZPJMESA-N
SMILES :C(O)(=O)[C@H](COC(C)(C)C)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
CAS DataBase Reference :71989-33-8(CAS DataBase Reference)
alpha :25 º (c=1,EtOAc 24 ºC)
Boiling point :510.36°C (rough estimate)
Density :1.2369 (rough estimate)
refractive index :24 ° (C=1, AcOEt)
storage temp. :2-8°C
solubility :Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form :powder to crystal
pka :3.44±0.10(Predicted)
color :White to Almost white
optical activity :[α]20/D +25.5±1°, c = 1% in ethyl acetate
BRN :3632013
InChI :InChI=1S/C22H25NO5/c1-22(2,3)28-13-19(20(24)25)23-21(26)27-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,23,26)(H,24,25)/t19-/m0/s1
InChIKey :REITVGIIZHFVGU-IBGZPJMESA-N
SMILES :C(O)(=O)[C@H](COC(C)(C)C)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
CAS DataBase Reference :71989-33-8(CAS DataBase Reference)
Safety Information
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Description
Fmoc-Ser(tBu)-OH is an N-terminal protected reagent used in the peptide synthesis. Some of the reported examples are:- Total synthesis of an antibiotic, daptomycin, by cyclization via a chemoselective serine ligation.
- Preparation of MUC1, a T-cell helper peptide, using iterative pentafluorophenyl ester-mediated fragment condensations.
- Linear solid-phase peptide synthesis of ubiquitin and diubiquitin.
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