N-(5-tert-Butylisoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-ylethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea
![N-(5-tert-Butylisoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-ylethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea price.](/CAS2/GIF/950769-58-1.gif)
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- $28 - $5280
- Product name: N-(5-tert-Butylisoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-ylethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea
- CAS: 950769-58-1
- MF: C29H32N6O4S
- MW: 560.67
- EINECS:
- MDL Number:MFCD18074524
- Synonyms:N-(5-tert-Butylisoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-ylethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea AC-220;quizartinib (FLT3 inhibitor);1-(5-(tert-Butyl)isoxazol-3-yl)-3-(4-(7-(2-morpholinoethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-y;Quizartinib AC-220;2-(4-AMinophenyl)-7-(2-Morpholin-4-yl-ethoxy)iMidazo[2,1-b]-[1,3]benzothiazole;N-(5-tert-Butylisoxazol-3-yl)-N'-{4-[7-(2-Morpholin-4-ylethoxy)iMidazo[2,1-b][1,3]benzothiazol-2-yl];AC220 (Quizartinib);AC220 (Quizartinib, AC010220)
42 prices
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Brand
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Tocris
- TRC
- Usbiological
Package
- 20mg
- 25mg
- 50mg
- 10
- 100mg
- 200mg
- 500μg
- 1MG
- 1unit
- 5MG
- 10MG
- 50
- 10mM(in 1mL DMSO)
- 250mg
- 500mg
- 1g
- 2g
- 5g
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1003-M100
- Product descriptionQuizartinib ≥95%
- Packaging100mg
- Price$1458
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberV2458
- Product descriptionQuizartinib
- Packaging100mg
- Price$240
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000393
- Product descriptionQUIZARTINIB 95.00%
- Packaging1MG
- Price$705.57
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000393
- Product descriptionQUIZARTINIB 95.00%
- Packaging5MG
- Price$826.07
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000393
- Product descriptionQUIZARTINIB 95.00%
- Packaging10MG
- Price$890.39
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5793
- Product descriptionQuizartinib(AC220)
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5793
- Product descriptionQuizartinib(AC220)
- Packaging5mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5793
- Product descriptionQuizartinib(AC220)
- Packaging10mM(in 1mL DMSO)
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5793
- Product descriptionQuizartinib(AC220)
- Packaging25mg
- Price$165
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5793
- Product descriptionQuizartinib(AC220)
- Packaging100mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60241
- Product descriptionQuizartinib(AC220) ≥98%
- Packaging20mg
- Price$238
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154726
- Product descriptionQuizartinib (AC220) >98%
- Packaging100mg
- Price$542.3
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154726
- Product descriptionQuizartinib (AC220) >98%
- Packaging250mg
- Price$986
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154726
- Product descriptionQuizartinib (AC220) >98%
- Packaging1g
- Price$2023
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFQ32834
- Product descriptionQuizartinib
- Packaging10mg
- Price$40
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFQ32834
- Product descriptionQuizartinib
- Packaging25mg
- Price$75
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | SYN-1003-M100 | Quizartinib ≥95% | 100mg | $1458 | 2021-12-16 | Buy |
| AK Scientific | V2458 | Quizartinib | 100mg | $240 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000393 | QUIZARTINIB 95.00% | 1MG | $705.57 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000393 | QUIZARTINIB 95.00% | 5MG | $826.07 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000393 | QUIZARTINIB 95.00% | 10MG | $890.39 | 2021-12-16 | Buy |
| ApexBio Technology | A5793 | Quizartinib(AC220) | 1unit | $28 | 2021-12-16 | Buy |
| ApexBio Technology | A5793 | Quizartinib(AC220) | 5mg | $55 | 2021-12-16 | Buy |
| ApexBio Technology | A5793 | Quizartinib(AC220) | 10mM(in 1mL DMSO) | $70 | 2021-12-16 | Buy |
| ApexBio Technology | A5793 | Quizartinib(AC220) | 25mg | $165 | 2021-12-16 | Buy |
| ApexBio Technology | A5793 | Quizartinib(AC220) | 100mg | $420 | 2021-12-16 | Buy |
| Arctom | CFN60241 | Quizartinib(AC220) ≥98% | 20mg | $238 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb154726 | Quizartinib (AC220) >98% | 100mg | $542.3 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb154726 | Quizartinib (AC220) >98% | 250mg | $986 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb154726 | Quizartinib (AC220) >98% | 1g | $2023 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FQ32834 | Quizartinib | 10mg | $40 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FQ32834 | Quizartinib | 25mg | $75 | 2021-12-16 | Buy |
Properties
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml)
form :White powder.
pka :12.59±0.70(Predicted)
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml)
form :White powder.
pka :12.59±0.70(Predicted)
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Quizartinib is an inhibitor of FMS-related tyrosine kinase 3 (FLT3; Kd = 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases. It inhibits the proliferation of the human leukemia cell line MV4-11, which harbors a homozygous FLT3-ITD mutation, with an IC50 value of 0.56 nM. At 1 mg/kg/day, quizartinib has been shown to extend survival in a mouse model of FLT3-ITD acute myeloid leukemia and to eradicate tumors in an FLT3-dependent mouse xenograft model at 10 mg/kg.More related product prices
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![N-(5-tert-Butylisoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-ylethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea](https://img.chemicalbook.com/ProductImageEN/2019-7/small/d0f9eddf-03c2-49b4-8c84-704ff6bf3b4e.png){kind=small}