Argatroban Impurity 23
|
- $299 - $1980
- Product name: Argatroban Impurity 23
- CAS: 1356847-56-7
- MF: C23H33D3N6O5S
- MW: 511.652625334
- EINECS:
- MDL Number:MFCD09839946
- Synonyms:Argatroban-d3 (Mixture Of Diastereomers);[2H3]-Argatroban;Argatroban-d3 (hydrochloride)
3 prices
Selected condition：
Brand
- Cayman Chemical
- TRC
Package
- 1mg
- 5mg
- 10mg
- ManufacturerCayman Chemical
- Product number25757
- Product descriptionArgatroban-d3 (hydrochloride)
- Packaging1mg
- Price$299
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number25757
- Product descriptionArgatroban-d3 (hydrochloride)
- Packaging5mg
- Price$1340
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberA769002
- Product descriptionArgatroban-d3
- Packaging10mg
- Price$1980
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Cayman Chemical | 25757 | Argatroban-d3 (hydrochloride) | 1mg | $299 | 2024-03-01 | Buy |
| Cayman Chemical | 25757 | Argatroban-d3 (hydrochloride) | 5mg | $1340 | 2024-03-01 | Buy |
| TRC | A769002 | Argatroban-d3 | 10mg | $1980 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMF: soluble,DMSO: soluble,Methanol: soluble
form :A solid
solubility :DMF: soluble,DMSO: soluble,Methanol: soluble
form :A solid
Safety Information
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Description
Argatroban-d3 is intended for use as an internal standard for the quantification of argatroban by GC- or LC-MS. Argatroban is a reversible inhibitor of thrombin (IC50s = 0.01 and 0.09 μM for the free and clot-bound forms, respectively). It is selective for thrombin over factor Xa, trypsin, plasmin, and tissue plasminogen activator (Kis = 0.0045, 53, 0.19, 25.7, and 87.7 μM, respectively). It inhibits thrombin-induced platelet aggregation in washed isolated guinea pig platelets with an IC50 value of 0.077 μM. Argatroban (3.2 mg/kg, s.c.) decreases thrombus formation in a guinea pig model of iron chloride-induced arterial thrombosis. Formulations containing argatroban have been used in the prevention or treatment of thrombosis in patients with heparin-induced thrombocytopenia.More related product prices
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