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ChemicalBook >> CAS DataBase List >> BAY-598 R-isomer

BAY-598 R-isomer

BAY-598 R-isomer price.
  • $41 - $634
  • Product name: BAY-598 R-isomer
  • CAS: 1906920-28-2
  • MF: C22H20Cl2F2N6O3
  • MW: 525.34
  • EINECS:
  • MDL Number:
  • Synonyms:BAY-598 R-isomer;(R)-BAY-598;BAY598 Risomer,BAY 598 R isomer;Acetamide, N-[(4R)-1-[(cyanoamino)[[3-(difluoromethoxy)phenyl]imino]methyl]-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazol-4-yl]-N-ethyl-2-hydroxy-;N-[(4R)-1-[(cyanoamino)[[3-(difluoromethoxy)phenyl]imino]methyl]-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazol-4-yl]-N-ethyl-2-hydroxy-acetamide
10 prices
Selected condition:
Brand
  • aablocks
  • Arctom
  • Cayman Chemical
  • ChemScene
Package
  • 500μg
  • 1mg
  • 5mg
  • 10mg
  • Manufactureraablocks
  • Product numberAA01LIVM
  • Product description(R)-BAY-598 ≥98%
  • Packaging1mg
  • Price$72
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01LIVM
  • Product description(R)-BAY-598 ≥98%
  • Packaging5mg
  • Price$293
  • Updated2026-05-30
  • Buy
  • ManufacturerArctom
  • Product numberHY-19546A
  • Product description(R)-BAY-598
  • Packaging5mg
  • Price$556
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-19546A
  • Product description(R)-BAY-598
  • Packaging1mg
  • Price$140
  • Updated2026-05-26
  • Buy
  • ManufacturerCayman Chemical
  • Product number29174
  • Product description(R)-BAY-598 ≥98%
  • Packaging500μg
  • Price$41
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number29174
  • Product description(R)-BAY-598 ≥98%
  • Packaging1mg
  • Price$72
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number29174
  • Product description(R)-BAY-598 ≥98%
  • Packaging10mg
  • Price$544
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number29174
  • Product description(R)-BAY-598 ≥98%
  • Packaging5mg
  • Price$293
  • Updated2026-04-30
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0091076
  • Product description(R)-BAY-598
  • Packaging5mg
  • Price$634
  • Updated2026-06-04
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0091076
  • Product description(R)-BAY-598
  • Packaging1mg
  • Price$159
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA01LIVM (R)-BAY-598 ≥98% 1mg $72 2026-05-30 Buy
aablocks AA01LIVM (R)-BAY-598 ≥98% 5mg $293 2026-05-30 Buy
Arctom HY-19546A (R)-BAY-598 5mg $556 2026-05-26 Buy
Arctom HY-19546A (R)-BAY-598 1mg $140 2026-05-26 Buy
Cayman Chemical 29174 (R)-BAY-598 ≥98% 500μg $41 2026-04-30 Buy
Cayman Chemical 29174 (R)-BAY-598 ≥98% 1mg $72 2026-04-30 Buy
Cayman Chemical 29174 (R)-BAY-598 ≥98% 10mg $544 2026-04-30 Buy
Cayman Chemical 29174 (R)-BAY-598 ≥98% 5mg $293 2026-04-30 Buy
ChemScene CS-0091076 (R)-BAY-598 5mg $634 2026-06-04 Buy
ChemScene CS-0091076 (R)-BAY-598 1mg $159 2026-06-04 Buy

Properties

Boiling point :663.5±65.0 °C(Predicted)
Density :1.46±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: soluble
form :A solid
pka :13.34±0.10(Predicted)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

BAY-598 R-isomer is the R-isomer of BAY589. BAY-598 R-isomer may be used as a reference compound. BAY-598 is a potent, peptide-competitive chemical probe for SMYD2. BAY-598 has a unique chemotype relative to the current SMYD2 chemical probe LLY-507. BAY-598 inhibits in vitro methylation of p53K370 with IC50 = 27 nM and has more than 100-fold selectivity over other histone methyltransferases and other non-epigenetic targets. BAY-598 inhibits the methylation of p53K370 in cells with IC50 < 1 μM. (Further to this, BAY-598 has properties that are compatible with in vivo experiments.) A control compound, BAY-369, has also been developed. BAY-369 inhibits the in vitro methylation of p53K370 with IC50 > 70 micromolar.

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