BRL 50481
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- $9 - $2691.1
- Product name: BRL 50481
- CAS: 433695-36-4
- MF: C9H12N2O4S
- MW: 244.27
- EINECS:1592732-453-0
- MDL Number:MFCD03039912
- Synonyms:5-NITRO-2,N,N-TRIMETHYLBENZENESULFONAMIDE;BRL 50481;N,N,2-TRIMETHYL-5-NITRO-BENZENESULFONAMIDE;3-(N,N-Dimethylsulfonamido)-4-methylnitrobenzene,5-Nitro-2-N,N-trimethylbenzenesulfonamide;Benzenesulfonamide, N,N,2-trimethyl-5-nitro-;-50481;BRL-50481, Selective PDE7 inhibitor;BRL-50481 (BRL50481
77 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Thermo Scientific Chemicals
- Tocris
- TRC
- Usbiological
Package
- 50
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200MG
- 250mg
- 500mg
- 1g
- 10
- 5g
- 10g
- 25g
- Manufactureraablocks
- Product numberAA00D9NY
- Product descriptionN,N,2-Trimethyl-5-Nitrobenzenesulfonamide 99%
- Packaging1mg
- Price$9
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00D9NY
- Product descriptionN,N,2-Trimethyl-5-Nitrobenzenesulfonamide 99%
- Packaging5mg
- Price$16
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00D9NY
- Product descriptionN,N,2-Trimethyl-5-Nitrobenzenesulfonamide 99%
- Packaging10mg
- Price$22
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00D9NY
- Product descriptionN,N,2-Trimethyl-5-Nitrobenzenesulfonamide 99%
- Packaging25mg
- Price$34
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00D9NY
- Product descriptionN,N,2-Trimethyl-5-Nitrobenzenesulfonamide 99%
- Packaging50mg
- Price$55
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00D9NY
- Product descriptionN,N,2-Trimethyl-5-Nitrobenzenesulfonamide 98%
- Packaging250mg
- Price$63
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00D9NY
- Product descriptionN,N,2-Trimethyl-5-Nitrobenzenesulfonamide 98%
- Packaging1g
- Price$140
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00D9NY
- Product descriptionN,N,2-Trimethyl-5-Nitrobenzenesulfonamide 98%
- Packaging5g
- Price$407
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00D9NY
- Product descriptionN,N,2-Trimethyl-5-Nitrobenzenesulfonamide 98%
- Packaging10g
- Price$674
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00D9NY
- Product descriptionN,N,2-Trimethyl-5-Nitrobenzenesulfonamide 98%
- Packaging25g
- Price$1342
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberS86711
- Product descriptionBRL 50481 98%
- Packaging5G
- Price$440
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberS86711
- Product descriptionBRL 50481 98%
- Packaging5G
- Price$440
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberS86711
- Product descriptionBRL 50481 98%
- Packaging1G
- Price$110
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberS86711
- Product descriptionBRL 50481 98%
- Packaging1G
- Price$110
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number4516CJ
- Product descriptionN,N,2-Trimethyl-5-nitrobenzenesulfonamide
- Packaging100mg
- Price$212
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024926
- Product descriptionBRL 50481 95.00%
- Packaging100MG
- Price$1593.9
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00D9NY | N,N,2-Trimethyl-5-Nitrobenzenesulfonamide 99% | 1mg | $9 | 2026-05-28 | Buy |
| aablocks | AA00D9NY | N,N,2-Trimethyl-5-Nitrobenzenesulfonamide 99% | 5mg | $16 | 2026-05-28 | Buy |
| aablocks | AA00D9NY | N,N,2-Trimethyl-5-Nitrobenzenesulfonamide 99% | 10mg | $22 | 2026-05-28 | Buy |
| aablocks | AA00D9NY | N,N,2-Trimethyl-5-Nitrobenzenesulfonamide 99% | 25mg | $34 | 2026-05-28 | Buy |
| aablocks | AA00D9NY | N,N,2-Trimethyl-5-Nitrobenzenesulfonamide 99% | 50mg | $55 | 2026-05-28 | Buy |
| aablocks | AA00D9NY | N,N,2-Trimethyl-5-Nitrobenzenesulfonamide 98% | 250mg | $63 | 2026-05-28 | Buy |
| aablocks | AA00D9NY | N,N,2-Trimethyl-5-Nitrobenzenesulfonamide 98% | 1g | $140 | 2026-05-28 | Buy |
| aablocks | AA00D9NY | N,N,2-Trimethyl-5-Nitrobenzenesulfonamide 98% | 5g | $407 | 2026-05-28 | Buy |
| aablocks | AA00D9NY | N,N,2-Trimethyl-5-Nitrobenzenesulfonamide 98% | 10g | $674 | 2026-05-28 | Buy |
| aablocks | AA00D9NY | N,N,2-Trimethyl-5-Nitrobenzenesulfonamide 98% | 25g | $1342 | 2026-05-28 | Buy |
| ACHEMBLOCK | S86711 | BRL 50481 98% | 5G | $440 | 2026-05-25 | Buy |
| ACHEMBLOCK | S86711 | BRL 50481 98% | 5G | $440 | 2026-05-27 | Buy |
| ACHEMBLOCK | S86711 | BRL 50481 98% | 1G | $110 | 2026-05-25 | Buy |
| ACHEMBLOCK | S86711 | BRL 50481 98% | 1G | $110 | 2026-05-27 | Buy |
| AK Scientific | 4516CJ | N,N,2-Trimethyl-5-nitrobenzenesulfonamide | 100mg | $212 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0024926 | BRL 50481 95.00% | 100MG | $1593.9 | 2021-12-16 | Buy |
Properties
Melting point :65-67°C
Boiling point :391.1±52.0 °C(Predicted)
Density :1.334±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 12 mg/mL
form :solid
pka :-5+-.0.70(Predicted)
color :white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChI :1S/C9H12N2O4S/c1-7-4-5-8(11(12)13)6-9(7)16(14,15)10(2)3/h4-6H,1-3H3
InChIKey :IFIUFCJFLGCQPH-UHFFFAOYSA-N
SMILES :CN(C)S(=O)(=O)c1cc(ccc1C)[N+]([O-])=O
Boiling point :391.1±52.0 °C(Predicted)
Density :1.334±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 12 mg/mL
form :solid
pka :-5+-.0.70(Predicted)
color :white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChI :1S/C9H12N2O4S/c1-7-4-5-8(11(12)13)6-9(7)16(14,15)10(2)3/h4-6H,1-3H3
InChIKey :IFIUFCJFLGCQPH-UHFFFAOYSA-N
SMILES :CN(C)S(=O)(=O)c1cc(ccc1C)[N+]([O-])=O
Safety Information
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Description
BRL 50481 is a potent, selective inhibitor of phosphodiesterase (PDE) 7, inhibiting human recombinant PDE7A1 with a Ki value of 180 nM. It is much less effective against PDE3 and PDE4 and is without effect against PDE1B, PDE1C, PDE2, and PDE5. Through its effects on PDE7A1, BRL 50481 enhances the inhibitory effects of the PDE4 blocker rolipram on monocytes, lung macrophages, and CD8+ T-lymphocytes. BRL 50481, at 30 μM, promotes apoptosis in chronic lymphocytic leukemia cells overexpressing PDE7B, suggesting that this compound also acts against PDE7B. BRL 50481 can be used to evaluate the role of PDE7 isoforms in intracellular signaling.More related product prices
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Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
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InvivoChem
Hefei TNJ Chemical Industry Co.,Ltd.
HANGZHOU LEAP CHEM CO., LTD.
Hebei Chuanghai Biotechnology Co., Ltd
TargetMol Chemicals Inc.
