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ChemicalBook >> CAS DataBase List >> Brinzolamide-d5

Brinzolamide-d5

Brinzolamide-d5 price.
  • $279 - $2783
  • Product name: Brinzolamide-d5
  • CAS: 1217651-02-9
  • MF: C12H21N3O5S3
  • MW: 383.5
  • EINECS:
  • MDL Number:
  • Synonyms:[2H5]-Brinzolamide;Brinzolamide-d5
6 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • TRC
Package
  • 500μg
  • 0.5MG
  • 1mg
  • 5MG
  • ManufacturerAK Scientific
  • Product number7669DG
  • Product descriptionBrinzolamide-d5
  • Packaging1mg
  • Price$646
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberRDL0006690
  • Product descriptionBRINZOLAMIDE-D5 95.00%
  • Packaging0.5MG
  • Price$797.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberRDL0006690
  • Product descriptionBRINZOLAMIDE-D5 95.00%
  • Packaging5MG
  • Price$2783
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number30006
  • Product descriptionBrinzolamide-d5
  • Packaging500μg
  • Price$279
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number30006
  • Product descriptionBrinzolamide-d5
  • Packaging1mg
  • Price$501
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberB677602
  • Product descriptionBrinzolamide-d5
  • Packaging5mg
  • Price$1980
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 7669DG Brinzolamide-d5 1mg $646 2021-12-16 Buy
American Custom Chemicals Corporation RDL0006690 BRINZOLAMIDE-D5 95.00% 0.5MG $797.5 2021-12-16 Buy
American Custom Chemicals Corporation RDL0006690 BRINZOLAMIDE-D5 95.00% 5MG $2783 2021-12-16 Buy
Cayman Chemical 30006 Brinzolamide-d5 500μg $279 2024-03-01 Buy
Cayman Chemical 30006 Brinzolamide-d5 1mg $501 2024-03-01 Buy
TRC B677602 Brinzolamide-d5 5mg $1980 2021-12-16 Buy

Properties

storage temp. :Refrigerator
solubility :Ethanol
form :Solid
color :Crystalline

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Brinzolamide-d5 is intended for use as an internal standard for the quantification of brinzolamide by GC- or LC-MS. Brinzolamide is a potent inhibitor of carbonic anhydrase II (CAII) and CAIV (IC50s = 3.19 and 45.3 nM, respectively). It is selective for CAII and CAIV over CAI (IC50 = ~1,365 nM). Brinzolamide (30 mg/kg) reduces intestinal charcoal meal progression by 44% and prolongs pentobarbital sodium-induced sleep time by 35% in mice. Topical administration of brinzolamide (0.25, 0.5, and 1 mg/eye) reduces intraocular pressure in a rabbit model of spontaneous ocular hypertension. It also reduces intraocular pressure in a cynomolgus monkey model of argon laser trabeculoplasty-induced ocular hypertension. Formulations containing brinzolamide have been used in the treatment of glaucoma and ocular hypertension.

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