COLIVELIN
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- $127.5 - $2475
- Product name: COLIVELIN
- CAS: 867021-83-8
- MF: C119H206N32O35
- MW: 2645.15
- EINECS:21-183-8
- MDL Number:MFCD08704663
- Synonyms:COLIVELIN;H-SER-ALA-LEU-LEU-ARG-SER-ILE-PRO-ALA-PRO-ALA-GLY-ALA-SER-ARG-LEU-LEU-LEU-LEU-THR-GLY-GLU-ILE-ASP-LEU-PRO-OH;Colivelin (human);SER-ALA-LEU-LEU-ARG-SER-ILE-PRO-ALA-PRO-ALA-GLY-ALA-SER-ARG-LEU-LEU-LEU-LEU-THR-GLY-GLU-ILE-ASP-LEU-PRO;L-Proline, L-seryl-L-alanyl-L-leucyl-L-leucyl-L-arginyl-L-seryl-L-isoleucyl-L-prolyl-L-alanyl-L-prolyl-L-alanylglycyl-L-alanyl-L-seryl-L-arginyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-threonylglycyl-L-α-glutamyl-L-isoleucyl-L-α-aspartyl-L-leucyl-;Colivelin trifluoroacetate salt H-Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro-OH trifluoroacetate salt;Amyloid-β,β-amyloid peptide,STAT,Colivelin,Inhibitor,inhibit,disease,Neuroprotectant,Abeta,ischemic,brain,neurological,alzheimer,injury;SALLRSIPAPAGASRLLLLTGEIDLP
15 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- Tocris
- TRC
- Usbiological
Package
- 250ug
- 500ug
- 500μg
- 0.5MG
- 1mg
- 2mg
- 5MG
- 500U
- ManufacturerAK Scientific
- Product number4074EB
- Product descriptionColivelin
- Packaging1mg
- Price$503
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPEP0009170
- Product descriptionCOLIVELIN 95.00%
- Packaging0.5MG
- Price$625
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPEP0009170
- Product descriptionCOLIVELIN 95.00%
- Packaging1MG
- Price$788
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPEP0009170
- Product descriptionCOLIVELIN 95.00%
- Packaging5MG
- Price$1834.8
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7546
- Product descriptionColivelin
- Packaging500ug
- Price$276
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC109801
- Product descriptionColivelin trifluoroacetate salt H-Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro-OH trifluoroacetate salt
- Packaging250ug
- Price$127.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC109801
- Product descriptionColivelin trifluoroacetate salt H-Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro-OH trifluoroacetate salt
- Packaging500ug
- Price$225
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC109801
- Product descriptionColivelin trifluoroacetate salt H-Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro-OH trifluoroacetate salt
- Packaging1mg
- Price$388
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC109801
- Product descriptionColivelin trifluoroacetate salt H-Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro-OH trifluoroacetate salt
- Packaging2mg
- Price$660
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC109801
- Product descriptionColivelin trifluoroacetate salt H-Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro-OH trifluoroacetate salt
- Packaging5mg
- Price$1434.8
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number24239
- Product descriptionColivelin ≥95%
- Packaging500μg
- Price$242
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number24239
- Product descriptionColivelin ≥95%
- Packaging1mg
- Price$364
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number3945
- Product descriptionColivelin
- Packaging500U
- Price$314
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberC641530
- Product descriptionColivelin
- Packaging5mg
- Price$2475
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number255021
- Product descriptionColivelin
- Packaging500ug
- Price$573
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 4074EB | Colivelin | 1mg | $503 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PEP0009170 | COLIVELIN 95.00% | 0.5MG | $625 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PEP0009170 | COLIVELIN 95.00% | 1MG | $788 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PEP0009170 | COLIVELIN 95.00% | 5MG | $1834.8 | 2021-12-16 | Buy |
| ApexBio Technology | B7546 | Colivelin | 500ug | $276 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC109801 | Colivelin trifluoroacetate salt H-Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro-OH trifluoroacetate salt | 250ug | $127.5 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC109801 | Colivelin trifluoroacetate salt H-Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro-OH trifluoroacetate salt | 500ug | $225 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC109801 | Colivelin trifluoroacetate salt H-Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro-OH trifluoroacetate salt | 1mg | $388 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC109801 | Colivelin trifluoroacetate salt H-Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro-OH trifluoroacetate salt | 2mg | $660 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC109801 | Colivelin trifluoroacetate salt H-Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro-OH trifluoroacetate salt | 5mg | $1434.8 | 2021-12-16 | Buy |
| Cayman Chemical | 24239 | Colivelin ≥95% | 500μg | $242 | 2024-03-01 | Buy |
| Cayman Chemical | 24239 | Colivelin ≥95% | 1mg | $364 | 2024-03-01 | Buy |
| Tocris | 3945 | Colivelin | 500U | $314 | 2021-12-16 | Buy |
| TRC | C641530 | Colivelin | 5mg | $2475 | 2021-12-16 | Buy |
| Usbiological | 255021 | Colivelin | 500ug | $573 | 2021-12-16 | Buy |
Properties
Density :1.42±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in DMSO; insoluble in EtOH; ≥15 mg/mL in H2O
form :solid
color :White
Water Solubility :Soluble to 1 mg/ml in 20% ethanol / water
storage temp. :Store at -20°C
solubility :insoluble in DMSO; insoluble in EtOH; ≥15 mg/mL in H2O
form :solid
color :White
Water Solubility :Soluble to 1 mg/ml in 20% ethanol / water
Safety Information
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Description
Colivelin is a potent synthetic peptide activator of STAT3 that has neuroprotective activity. It protects approximately 50 and 100% of mouse primary cortical neurons from cell death induced by amyloid β (1-43) (Aβ43) when used at concentrations of 10 and 100 fM, respectively. Colivelin protects against cell death induced by V642I-APP in a CaM kinase IV (CaMKIV) and STAT3-dependent manner. It increases STAT3 phosphorylation in vitro and in vivo, an effect that correlates with improvements in working memory. Colivelin (10 pmol every six days) rescues deficits in spatial working memory in a mouse model of Alzheimer’s disease induced by intracerebroventricular injection of Aβ25-35. It also improves motor performance and prolongs survival in a mouse model of amyotrophic lateral sclerosis (ALS).Related product price
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