CYCLOPIAZONIC ACID
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- $25 - $850
- Product name: CYCLOPIAZONIC ACID
- CAS: 18172-33-3
- MF: C20H20N2O3
- MW: 336.38
- EINECS:
- MDL Number:MFCD00167445
- Synonyms:-Cyclopiazonic acid / CPA;Cyclopiazonic acid from Penicillium grisefulvum;Cyclopiazonic acid (CPA);Cyclopiazonic acid, FroM PenicilliuM griseofulvuM;(6aR,11aS,11bR)-10-acetyl-11-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-9H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9-one;(6a-alpha,11a,11b-alpha)--10-acetyl-7-dimethyl-11-hydroxy- ;9h-pyrrolo(1’,2’:2,3)isoindolo(4,5,6-cd)indol-9-one,2,6,6a,7,11a,11b-hexahydro ;(6AA, 10Z, 11AB, 11BA)-6A,7,11A,11B-TETRAHYDRO-10-(1-HYDROXYETHYLIDENE)-7,7- DIMETHYL-6H-PYRROLO [1',2':2,3]ISOINDOLO [4,5,6-CD]INDOLE-9,11 (2H,10H)-DIONE
33 prices
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Brand
- AK Scientific
- ApexBio Technology
- Arctom
- AvaChem
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Sigma-Aldrich
- Thermo Scientific Chemicals
- TRC
Package
- 25mg
- 10mM*1mLinDMSO(Solution)
- 2mg
- 50mg
- 1mg
- 5mg
- 10mg
- 10mM*1mLinDMSO(Solid+Solvent)
- ManufacturerAK Scientific
- Product number8500AJ
- Product descriptionCyclopiazonic Acid,
- Packaging1mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6647
- Product descriptionCyclopiazonic acid
- Packaging5mg
- Price$105
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB6647
- Product descriptionCyclopiazonic Acid,
- Packaging10mg
- Price$138
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6647
- Product descriptionCyclopiazonic Acid,
- Packaging5mg
- Price$79
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6647
- Product descriptionCyclopiazonic acid
- Packaging10mg
- Price$183
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-N6771
- Product descriptionCyclopiazonic acid 99.86%
- Packaging10mg
- Price$228
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-N6771
- Product descriptionCyclopiazonic acid 99.86%
- Packaging5mg
- Price$143
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-N6771
- Product descriptionCyclopiazonic acid 99.86%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$150
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-N6771
- Product descriptionCyclopiazonic acid 99.86%
- Packaging10mM*1mLinDMSO(Solution)
- Price$157
- Updated2026-05-26
- Buy
- ManufacturerAvaChem
- Product number6240
- Product descriptionCyclopiazonic acid 98%
- Packaging5mg
- Price$78
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number6240
- Product descriptionCyclopiazonic acid 98%
- Packaging25mg
- Price$312
- Updated2026-05-22
- Buy
- ManufacturerBiosynth
- Product numberFC45557
- Product descriptionCyclopiazonic acid
- Packaging25mg
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFC45557
- Product descriptionCyclopiazonic acid
- Packaging10mg
- Price$270
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFC45557
- Product descriptionCyclopiazonic acid
- Packaging50mg
- Price$850
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFC45557
- Product descriptionCyclopiazonic acid
- Packaging2mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFC45557
- Product descriptionCyclopiazonic acid
- Packaging5mg
- Price$150
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8500AJ | Cyclopiazonic Acid, | 1mg | $125 | 2021-12-16 | Buy |
| ApexBio Technology | B6647 | Cyclopiazonic acid | 5mg | $105 | 2026-05-06 | Buy |
| ApexBio Technology | B6647 | Cyclopiazonic Acid, | 10mg | $138 | 2021-12-16 | Buy |
| ApexBio Technology | B6647 | Cyclopiazonic Acid, | 5mg | $79 | 2021-12-16 | Buy |
| ApexBio Technology | B6647 | Cyclopiazonic acid | 10mg | $183 | 2026-05-06 | Buy |
| Arctom | HY-N6771 | Cyclopiazonic acid 99.86% | 10mg | $228 | 2026-05-26 | Buy |
| Arctom | HY-N6771 | Cyclopiazonic acid 99.86% | 5mg | $143 | 2026-05-26 | Buy |
| Arctom | HY-N6771 | Cyclopiazonic acid 99.86% | 10mM*1mLinDMSO(Solid+Solvent) | $150 | 2026-05-26 | Buy |
| Arctom | HY-N6771 | Cyclopiazonic acid 99.86% | 10mM*1mLinDMSO(Solution) | $157 | 2026-05-26 | Buy |
| AvaChem | 6240 | Cyclopiazonic acid 98% | 5mg | $78 | 2026-05-22 | Buy |
| AvaChem | 6240 | Cyclopiazonic acid 98% | 25mg | $312 | 2026-05-22 | Buy |
| Biosynth | FC45557 | Cyclopiazonic acid | 25mg | $550 | 2021-12-16 | Buy |
| Biosynth | FC45557 | Cyclopiazonic acid | 10mg | $270 | 2021-12-16 | Buy |
| Biosynth | FC45557 | Cyclopiazonic acid | 50mg | $850 | 2021-12-16 | Buy |
| Biosynth | FC45557 | Cyclopiazonic acid | 2mg | $80 | 2021-12-16 | Buy |
| Biosynth | FC45557 | Cyclopiazonic acid | 5mg | $150 | 2021-12-16 | Buy |
Properties
Melting point :245-246°C
Boiling point :472.86°C (rough estimate)
Density :1.2171 (rough estimate)
refractive index :1.5700 (estimate)
storage temp. :-20°C
solubility :DMSO: soluble
form :powder
pka :4.50±1.00(Predicted)
color :white to off-white
Water Solubility :Soluble in DMSO (100 mM), ethanol (5 mM), DMF (~20 mg/ml), and 1:1 DMSO:PBS(pH 7.2) (0.5 mg/ml). Insoluble in water.
InChI :1S/C20H22N2O3/c1-10(23)15-18(24)17-12-9-21-14-7-5-6-11(16(12)14)8-13(17)20(2,3)22(4)19(15)25/h5-7,9,13,17,21,23H,8H2,1-4H3/b15-10-
InChIKey :WJCPGKDPOYBOOJ-GDNBJRDFSA-N
SMILES :CN1C(=O)C(=C(\C)O)\C(=O)C2C(Cc3cccc4[nH]cc2c34)C1(C)C
EPA Substance Registry System :Cyclopiazonic acid (18172-33-3)
Boiling point :472.86°C (rough estimate)
Density :1.2171 (rough estimate)
refractive index :1.5700 (estimate)
storage temp. :-20°C
solubility :DMSO: soluble
form :powder
pka :4.50±1.00(Predicted)
color :white to off-white
Water Solubility :Soluble in DMSO (100 mM), ethanol (5 mM), DMF (~20 mg/ml), and 1:1 DMSO:PBS(pH 7.2) (0.5 mg/ml). Insoluble in water.
InChI :1S/C20H22N2O3/c1-10(23)15-18(24)17-12-9-21-14-7-5-6-11(16(12)14)8-13(17)20(2,3)22(4)19(15)25/h5-7,9,13,17,21,23H,8H2,1-4H3/b15-10-
InChIKey :WJCPGKDPOYBOOJ-GDNBJRDFSA-N
SMILES :CN1C(=O)C(=C(\C)O)\C(=O)C2C(Cc3cccc4[nH]cc2c34)C1(C)C
EPA Substance Registry System :Cyclopiazonic acid (18172-33-3)
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Cyclopiazonic acid is a mycotoxin produced by molds including certain species of Penicillium and Aspergillus. Its toxicity is linked to its ability to specifically and reversibly inhibit sarco-endoplasmic reticulum Ca2+-ATPases (SERCA; IC50 = 0.6 μM). Cyclopiazonic acid does not inhibit a wide variety of other types of membrane-bound ATPases. It effectively inhibits SERCA in intact tissue, in smooth muscle and endothelium, as well as in isolated cells.More related product prices
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Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
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SHANGHAI KEAN TECHNOLOGY CO., LTD.
NANJING YINGWEN BIOTECHNOLOGY CO LTD
J & K SCIENTIFIC LTD.
3B Pharmachem (Wuhan) International Co.,Ltd.
