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ChemicalBook >> CAS DataBase List >> Cdc7/Cdk9 Inhibitor

Cdc7/Cdk9 Inhibitor

Cdc7/Cdk9 Inhibitor price.
  • $35 - $2260
  • Product name: Cdc7/Cdk9 Inhibitor
  • CAS: 845714-00-3
  • MF: C12H11N3O
  • MW: 213.24
  • EINECS:
  • MDL Number:MFCD11870790
  • Synonyms:PHA-767491;CAY10572;1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one;PHA 767491 HYDROCHLORIDE;1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-onehydrochloride;2-(pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one;2-pyridin-4-yl-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one;PHA-767491HCL
41 prices
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  • aablocks
  • ACHEMBLOCK
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Cayman Chemical
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Tocris
  • TRC
  • Usbiological
Package
  • 50
  • 1MG
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  • 5mg
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  • 10mM*1mLinDMSO
  • 25mg
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  • 200mg
  • 250MG
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  • 10
  • 1G
  • 5G
  • 10mM(in1mLDMSO)
  • Manufactureraablocks
  • Product numberAA0038BU
  • Product description1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one
  • Packaging2mg
  • Price$44
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0038BU
  • Product description1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one
  • Packaging5mg
  • Price$56
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0038BU
  • Product description1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one
  • Packaging10mg
  • Price$70
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0038BU
  • Product description1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one
  • Packaging25mg
  • Price$99
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA0038BU
  • Product description1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one
  • Packaging50mg
  • Price$139
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0038BU
  • Product description1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one
  • Packaging100mg
  • Price$196
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0038BU
  • Product description1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one
  • Packaging200mg
  • Price$283
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberU135654
  • Product descriptionPHA767491 98%
  • Packaging1G
  • Price$565
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberU135654
  • Product descriptionPHA767491 98%
  • Packaging250MG
  • Price$215
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberU135654
  • Product descriptionPHA767491 98%
  • Packaging5G
  • Price$2260
  • Updated2026-05-27
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000310
  • Product descriptionPHA-767491 95.00%
  • Packaging1MG
  • Price$593.04
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000310
  • Product descriptionPHA-767491 95.00%
  • Packaging5MG
  • Price$795.33
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000310
  • Product descriptionPHA-767491 95.00%
  • Packaging10MG
  • Price$924.12
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA3721
  • Product descriptionPHA-767491
  • Packaging50mg
  • Price$285
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberA3721
  • Product descriptionPHA-767491
  • Packaging50mg
  • Price$259
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3721
  • Product descriptionPHA-767491
  • Packaging10mg
  • Price$72
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0038BU 1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one 2mg $44 2026-05-28 Buy
aablocks AA0038BU 1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one 5mg $56 2026-05-28 Buy
aablocks AA0038BU 1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one 10mg $70 2026-05-28 Buy
aablocks AA0038BU 1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one 25mg $99 2026-05-28 Buy
aablocks AA0038BU 1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one 50mg $139 2026-05-28 Buy
aablocks AA0038BU 1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one 100mg $196 2026-05-28 Buy
aablocks AA0038BU 1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one 200mg $283 2026-05-28 Buy
ACHEMBLOCK U135654 PHA767491 98% 1G $565 2026-05-27 Buy
ACHEMBLOCK U135654 PHA767491 98% 250MG $215 2026-05-27 Buy
ACHEMBLOCK U135654 PHA767491 98% 5G $2260 2026-05-27 Buy
American Custom Chemicals Corporation KIN0000310 PHA-767491 95.00% 1MG $593.04 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000310 PHA-767491 95.00% 5MG $795.33 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000310 PHA-767491 95.00% 10MG $924.12 2021-12-16 Buy
ApexBio Technology A3721 PHA-767491 50mg $285 2026-05-06 Buy
ApexBio Technology A3721 PHA-767491 50mg $259 2021-12-16 Buy
ApexBio Technology A3721 PHA-767491 10mg $72 2026-05-06 Buy

Properties

Density :1.287
storage temp. :Desiccate at RT
solubility :insoluble in H2O; insoluble in EtOH; ≥10.65 mg/mL in DMSO
form :solid
color :Off-white to light yellow
Stability :Hygroscopic
CAS DataBase Reference :845714-00-3

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

Cdc7 kinase is a key regulator of the S-phase of the cell cycle. It is known to promote the activity of DNA replication origins in eukaryotic organisms. Inhibition of Cdc7 kinase causes blockade of DNA synthesis in human cell lines. Tumor cells are then funneled into the apoptotic pathway in a p53-independent manner. Pharmacological inhibition of Cdc7 kinase can be an effective strategy for the development of oncologic therapeutics useful for treatment of cancers. PHA-767491 is a potent inhibitor of Cdc7 kinase with an IC50 value of 10 nM in the presence of 1.5 μM ATP. At 10 μM, PHA-767491 induces apoptotic cell death in multiple cancer cell types. PHA-767491 also inhibits Cdk9, a kinase involved in the phosphorylation of RNA polymerase II and in transcriptional regulation of gene expression, with an IC50 value of 34 nM.

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