Cenicriviroc
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- $60 - $20790
- Product name: Cenicriviroc
- CAS: 497223-25-3
- MF: C41H52N4O4S
- MW: 696.94
- EINECS:
- MDL Number:MFCD28502076
- Synonyms:Cenicriviroc;TAK652;Cenicriviroc mesylate (TAK-652);Cenicriviroc(TAK652);TAK-652; TAK652; TAK 652; TBR-652; TBR 652; TBR652; CENICRIVIROC.;CS-2572;TAK-652; TBR-652; TAK652; TBR652; TAK 652; TBR 652;TBR 652
15 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- TRC
Package
- 500μg
- 1mg
- 5MG
- 10mg
- 25mg
- 50mg
- 100mg
- 1g
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0005543
- Product descriptionCENICRIVIROC 95.00%
- Packaging5MG
- Price$500.98
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number23927
- Product descriptionCenicriviroc ≥95%
- Packaging500μg
- Price$60
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23927
- Product descriptionCenicriviroc ≥95%
- Packaging1mg
- Price$93
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23927
- Product descriptionCenicriviroc ≥95%
- Packaging5mg
- Price$344
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23927
- Product descriptionCenicriviroc ≥95%
- Packaging10mg
- Price$628
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-6148
- Product descriptionCenicriviroc 98.07%
- Packaging5mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6148
- Product descriptionCenicriviroc 98.07%
- Packaging10mg
- Price$260
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6148
- Product descriptionCenicriviroc 98.07%
- Packaging25mg
- Price$520
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6148
- Product descriptionCenicriviroc 98.07%
- Packaging50mg
- Price$880
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6148
- Product descriptionCenicriviroc 98.07%
- Packaging100mg
- Price$1570
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31001771
- Product descriptionCenicriviroc 95+%
- Packaging5mg
- Price$330
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31001771
- Product descriptionCenicriviroc 95+%
- Packaging10mg
- Price$520
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31001771
- Product descriptionCenicriviroc 95+%
- Packaging25mg
- Price$1050
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10316
- Product descriptionCenicriviroc >98%
- Packaging1g
- Price$2800
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberC256550
- Product descriptionCenicriviroc
- Packaging100mg
- Price$20790
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | INB0005543 | CENICRIVIROC 95.00% | 5MG | $500.98 | 2021-12-16 | Buy |
| Cayman Chemical | 23927 | Cenicriviroc ≥95% | 500μg | $60 | 2024-03-01 | Buy |
| Cayman Chemical | 23927 | Cenicriviroc ≥95% | 1mg | $93 | 2024-03-01 | Buy |
| Cayman Chemical | 23927 | Cenicriviroc ≥95% | 5mg | $344 | 2024-03-01 | Buy |
| Cayman Chemical | 23927 | Cenicriviroc ≥95% | 10mg | $628 | 2024-03-01 | Buy |
| ChemScene | CS-6148 | Cenicriviroc 98.07% | 5mg | $160 | 2021-12-16 | Buy |
| ChemScene | CS-6148 | Cenicriviroc 98.07% | 10mg | $260 | 2021-12-16 | Buy |
| ChemScene | CS-6148 | Cenicriviroc 98.07% | 25mg | $520 | 2021-12-16 | Buy |
| ChemScene | CS-6148 | Cenicriviroc 98.07% | 50mg | $880 | 2021-12-16 | Buy |
| ChemScene | CS-6148 | Cenicriviroc 98.07% | 100mg | $1570 | 2021-12-16 | Buy |
| Crysdot | CD31001771 | Cenicriviroc 95+% | 5mg | $330 | 2021-12-16 | Buy |
| Crysdot | CD31001771 | Cenicriviroc 95+% | 10mg | $520 | 2021-12-16 | Buy |
| Crysdot | CD31001771 | Cenicriviroc 95+% | 25mg | $1050 | 2021-12-16 | Buy |
| DC Chemicals | DC10316 | Cenicriviroc >98% | 1g | $2800 | 2021-12-16 | Buy |
| TRC | C256550 | Cenicriviroc | 100mg | $20790 | 2021-12-16 | Buy |
Properties
Boiling point :913.5±65.0 °C(Predicted)
Density :1.17±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 5 mg/ml
form :A crystalline solid
pka :12.96±0.70(Predicted)
Density :1.17±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 5 mg/ml
form :A crystalline solid
pka :12.96±0.70(Predicted)
Safety Information
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Description
Cenicriviroc is a dual antagonist of chemokine receptor types 2 and 5 (CCR2/CCR5). The receptors are found on Kupffer cells and hepatic stellate cells, and preclinical studies suggest its anti-inflammatory and anti-fibrotic activity. In the phase 2b CENTAUR study, cenicriviroc treatment for 1 year failed to achieve the primary outcome of a decrease in NAFLD activity score by ≥2 points with no worsening of fibrosis. Nonetheless, one of the key secondary outcomes, improvement in liver fibrosis without worsening of NASH, was achieved in 20% in the treatment group, compared with 10% in the placebo group. Besides, cenicriviroc reduced the serum levels interleukin- 6, C-reactive protein and fibrinogen, suggesting its action on inflammation that may not be reflected by crude histological assessment. A phase 3 study is planned.Related product price
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