Obeticholic Acid
|
- $28 - $800
- Product name: Obeticholic Acid
- CAS: 459789-99-2
- MF: C26H44O4
- MW: 420.63
- EINECS:810-245-2
- MDL Number:MFCD16621104
- Synonyms:6alpha-Ethyl-chenodeoxycholic acid;6-Ecdca;6alph;6-Ethyl-cdca;C15636;6-Ethylchenodeoxycholic acid(Obeticholic Acid);Obeticholic Acid;(3α,5β,6α,7α)-6-ethyl-3,7-dihydroxy-cholan-24-oic acid
22 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- ChemScene
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TRC
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- 5g
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3560-M025
- Product description6-ECDCA ≥95%(NMR)
- Packaging25mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY1328
- Product descriptionINT-747
- Packaging100mg
- Price$290
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4888
- Product descriptionObeticholicAcid
- Packaging25mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4888
- Product descriptionObeticholicAcid
- Packaging5mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4888
- Product descriptionObeticholicAcid
- Packaging100mg
- Price$470
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number11031
- Product description6-ECDCA ≥95%
- Packaging50mg
- Price$235
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number11031
- Product description6-ECDCA ≥95%
- Packaging25mg
- Price$125
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number11031
- Product description6-ECDCA ≥95%
- Packaging5mg
- Price$28
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number11031
- Product description6-ECDCA ≥95%
- Packaging10mg
- Price$53
- Updated2026-04-30
- Buy
- ManufacturerChemScene
- Product numberCS-3813
- Product descriptionObeticholicacid >98.0%
- Packaging50mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3813
- Product descriptionObeticholicacid >98.0%
- Packaging5mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3813
- Product descriptionObeticholicacid >98.0%
- Packaging200mg
- Price$350
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3813
- Product descriptionObeticholicacid >98.0%
- Packaging500mg
- Price$650
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7430
- Product descriptionObeticholicacid(INT-747) >98%
- Packaging1g
- Price$800
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7430
- Product descriptionObeticholicacid(INT-747) >98%
- Packaging250mg
- Price$400
- Updated2021-12-16
- Buy
- ManufacturerMatrix Scientific
- Product number132791
- Product description6-Ethylchenodeoxycholic acid 97%
- Packaging1g
- Price$450
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CR1-3560-M025 | 6-ECDCA ≥95%(NMR) | 25mg | $200 | 2021-12-16 | Buy |
| AK Scientific | Y1328 | INT-747 | 100mg | $290 | 2021-12-16 | Buy |
| ApexBio Technology | B4888 | ObeticholicAcid | 25mg | $200 | 2021-12-16 | Buy |
| ApexBio Technology | B4888 | ObeticholicAcid | 5mg | $50 | 2021-12-16 | Buy |
| ApexBio Technology | B4888 | ObeticholicAcid | 100mg | $470 | 2021-12-16 | Buy |
| Cayman Chemical | 11031 | 6-ECDCA ≥95% | 50mg | $235 | 2026-04-30 | Buy |
| Cayman Chemical | 11031 | 6-ECDCA ≥95% | 25mg | $125 | 2026-04-30 | Buy |
| Cayman Chemical | 11031 | 6-ECDCA ≥95% | 5mg | $28 | 2026-04-30 | Buy |
| Cayman Chemical | 11031 | 6-ECDCA ≥95% | 10mg | $53 | 2026-04-30 | Buy |
| ChemScene | CS-3813 | Obeticholicacid >98.0% | 50mg | $120 | 2021-12-16 | Buy |
| ChemScene | CS-3813 | Obeticholicacid >98.0% | 5mg | $50 | 2021-12-16 | Buy |
| ChemScene | CS-3813 | Obeticholicacid >98.0% | 200mg | $350 | 2021-12-16 | Buy |
| ChemScene | CS-3813 | Obeticholicacid >98.0% | 500mg | $650 | 2021-12-16 | Buy |
| DC Chemicals | DC7430 | Obeticholicacid(INT-747) >98% | 1g | $800 | 2021-12-16 | Buy |
| DC Chemicals | DC7430 | Obeticholicacid(INT-747) >98% | 250mg | $400 | 2021-12-16 | Buy |
| Matrix Scientific | 132791 | 6-Ethylchenodeoxycholic acid 97% | 1g | $450 | 2021-12-16 | Buy |
Properties
Melting point :108-110 °C
Boiling point :562.9±25.0 °C(Predicted)
Density :1.091
storage temp. :-20°C
solubility :Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 25 mg/ml)
form :White solid.
pka :4.76±0.10(Predicted)
color :White
optical activity :[α]/D +4 to +6°, c =1.0 in methanol
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
InChIKey :ZXERDUOLZKYMJM-IMGBAYNYNA-N
SMILES :C[C@]12CC[C@@H](O)C[C@@]1([H])[C@@H](CC)[C@@H](O)[C@@]1([H])[C@]3([H])CC[C@]([H])([C@H](C)CCC(=O)O)[C@@]3(C)CC[C@]21[H] |&1:1,4,7,9,12,14,16,20,22,29,33,r|
Boiling point :562.9±25.0 °C(Predicted)
Density :1.091
storage temp. :-20°C
solubility :Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 25 mg/ml)
form :White solid.
pka :4.76±0.10(Predicted)
color :White
optical activity :[α]/D +4 to +6°, c =1.0 in methanol
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
InChIKey :ZXERDUOLZKYMJM-IMGBAYNYNA-N
SMILES :C[C@]12CC[C@@H](O)C[C@@]1([H])[C@@H](CC)[C@@H](O)[C@@]1([H])[C@]3([H])CC[C@]([H])([C@H](C)CCC(=O)O)[C@@]3(C)CC[C@]21[H] |&1:1,4,7,9,12,14,16,20,22,29,33,r|
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Obeticholic acid is a potent and selective farnesoid X receptor agonist that promotes the flow of bile in the liver. The drug was approved by the USFDA for the treatment of the rare chronic liver disease primary biliary cholangitis (PBC) in combination with ursodeoxycholic acid (UDCA) in adults with inadequate response to UDCA or as a single agent therapy in adults unable to tolerate UDCA. Obeticholic acid was discovered at the Università de Perugia and developed by Intercept Pharmaceuticals. Obeticholic acid has also been granted orphan drug designation for the treatment of primary sclerosing cholangitis and primary biliary cirrhosis and has received breakthrough therapy designation for the treatment of patients with nonalcohol steatohepatitis (NASH) with liver fibrosis.Suppliers and manufacturers
Capot Chemical Co.,Ltd.
Nanjing Gold Pharmaceutical Technology Co. Ltd.
Beijing Cooperate Pharmaceutical Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
Nanjing ChemLin Chemical Industry Co., Ltd.
