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ChemicalBook >> CAS DataBase List >> DARAPLADIB

DARAPLADIB

DARAPLADIB price.
  • $16 - $1800
  • Product name: DARAPLADIB
  • CAS: 356057-34-6
  • MF: C36H38F4N4O2S
  • MW: 666.77
  • EINECS:
  • MDL Number:MFCD18251452
  • Synonyms:N-[2-(Diethylamino)ethyl]-N-[4'-(trifluoromethyl)-1,1'-biphenyl-4-ylmethyl]-2-[2-(4-fluorobenzylthio)-4-oxo-4,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-1-yl]acetamide;SB 435445;SB 480848;Darapladib API;Darapladib(SB-480848);N-[2-(diethylamino)ethyl]-2-[[(4-fluorophenyl)methyl]thio]-4,5,6,7-tetrahydro-4-oxo-N-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methyl]-1H-Cyclopentapyrimidine-1-acetamide;N-(2-(Diethylamino)ethyl)-2-(2-((4-fluorobenzyl)thio)-4-oxo-4,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-1-yl)-N-((4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)methyl)acetamide;DARAPLADIB;SB-480848;SB480848
Price48 Properties Safety Information Description
48 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • TRC
  • Usbiological
Package
  • 10mM(in1mLDMSO)
  • 1mg
  • 10mM(in 1mL DMSO)
  • 5mg
  • 10mg
  • 10mM*1mLinDMSO
  • 25MG
  • 50mg
  • 100MG
  • 250mg
  • 500mg
  • 1g
  • Manufactureraablocks
  • Product numberAA003P5Z
  • Product descriptionN-(2-(Diethylamino)Ethyl)-2-(2-((4-Fluorobenzyl)Thio)-4-Oxo-4,5,6,7-Tetrahydro-1H-Cyclopenta[D]Pyrimidin-1-Yl)-N-((4'-(Trifluoromethyl)-[1,1'-Biphenyl]-4-Yl)Methyl)Acetamide 98%
  • Packaging1mg
  • Price$16
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003P5Z
  • Product descriptionN-(2-(Diethylamino)Ethyl)-2-(2-((4-Fluorobenzyl)Thio)-4-Oxo-4,5,6,7-Tetrahydro-1H-Cyclopenta[D]Pyrimidin-1-Yl)-N-((4'-(Trifluoromethyl)-[1,1'-Biphenyl]-4-Yl)Methyl)Acetamide 98%
  • Packaging5mg
  • Price$30
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003P5Z
  • Product descriptionN-(2-(Diethylamino)Ethyl)-2-(2-((4-Fluorobenzyl)Thio)-4-Oxo-4,5,6,7-Tetrahydro-1H-Cyclopenta[D]Pyrimidin-1-Yl)-N-((4'-(Trifluoromethyl)-[1,1'-Biphenyl]-4-Yl)Methyl)Acetamide 98%
  • Packaging10mg
  • Price$49
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003P5Z
  • Product descriptionN-(2-(Diethylamino)Ethyl)-2-(2-((4-Fluorobenzyl)Thio)-4-Oxo-4,5,6,7-Tetrahydro-1H-Cyclopenta[D]Pyrimidin-1-Yl)-N-((4'-(Trifluoromethyl)-[1,1'-Biphenyl]-4-Yl)Methyl)Acetamide 95%
  • Packaging250mg
  • Price$274
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003P5Z
  • Product descriptionN-(2-(Diethylamino)Ethyl)-2-(2-((4-Fluorobenzyl)Thio)-4-Oxo-4,5,6,7-Tetrahydro-1H-Cyclopenta[D]Pyrimidin-1-Yl)-N-((4'-(Trifluoromethyl)-[1,1'-Biphenyl]-4-Yl)Methyl)Acetamide 95%
  • Packaging1g
  • Price$807
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberC-2941
  • Product descriptionDarapladib 98%
  • Packaging25MG
  • Price$100
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberC-2941
  • Product descriptionDarapladib 98%
  • Packaging1G
  • Price$435
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberC-2941
  • Product descriptionDarapladib 98%
  • Packaging100MG
  • Price$260
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN5724
  • Product descriptionDarapladib
  • Packaging100mg
  • Price$1660
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA684359
  • Product descriptionN-(2-(Diethylamino)ethyl)-2-(2-((4-fluorobenzyl)thio)-4-oxo-4,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-1-yl)-N-((4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)methyl)acetamide 98+%
  • Packaging1g
  • Price$1084
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA684359
  • Product descriptionN-(2-(Diethylamino)ethyl)-2-(2-((4-fluorobenzyl)thio)-4-oxo-4,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-1-yl)-N-((4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)methyl)acetamide 98+%
  • Packaging100mg
  • Price$218
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA684359
  • Product descriptionN-(2-(Diethylamino)ethyl)-2-(2-((4-fluorobenzyl)thio)-4-oxo-4,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-1-yl)-N-((4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)methyl)acetamide 98+%
  • Packaging250mg
  • Price$434
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA684359
  • Product descriptionN-(2-(Diethylamino)ethyl)-2-(2-((4-fluorobenzyl)thio)-4-oxo-4,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-1-yl)-N-((4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)methyl)acetamide 98+%
  • Packaging5mg
  • Price$76
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA684359
  • Product descriptionN-(2-(Diethylamino)ethyl)-2-(2-((4-fluorobenzyl)thio)-4-oxo-4,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-1-yl)-N-((4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)methyl)acetamide 98+%
  • Packaging10mg
  • Price$99
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA684359
  • Product descriptionN-(2-(Diethylamino)ethyl)-2-(2-((4-fluorobenzyl)thio)-4-oxo-4,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-1-yl)-N-((4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)methyl)acetamide 98+%
  • Packaging1mg
  • Price$43
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA684359
  • Product descriptionN-(2-(Diethylamino)ethyl)-2-(2-((4-fluorobenzyl)thio)-4-oxo-4,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-1-yl)-N-((4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)methyl)acetamide 98+%
  • Packaging50mg
  • Price$168
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA003P5Z N-(2-(Diethylamino)Ethyl)-2-(2-((4-Fluorobenzyl)Thio)-4-Oxo-4,5,6,7-Tetrahydro-1H-Cyclopenta[D]Pyrimidin-1-Yl)-N-((4'-(Trifluoromethyl)-[1,1'-Biphenyl]-4-Yl)Methyl)Acetamide 98% 1mg $16 2026-05-28 Buy
aablocks AA003P5Z N-(2-(Diethylamino)Ethyl)-2-(2-((4-Fluorobenzyl)Thio)-4-Oxo-4,5,6,7-Tetrahydro-1H-Cyclopenta[D]Pyrimidin-1-Yl)-N-((4'-(Trifluoromethyl)-[1,1'-Biphenyl]-4-Yl)Methyl)Acetamide 98% 5mg $30 2026-05-28 Buy
aablocks AA003P5Z N-(2-(Diethylamino)Ethyl)-2-(2-((4-Fluorobenzyl)Thio)-4-Oxo-4,5,6,7-Tetrahydro-1H-Cyclopenta[D]Pyrimidin-1-Yl)-N-((4'-(Trifluoromethyl)-[1,1'-Biphenyl]-4-Yl)Methyl)Acetamide 98% 10mg $49 2026-05-28 Buy
aablocks AA003P5Z N-(2-(Diethylamino)Ethyl)-2-(2-((4-Fluorobenzyl)Thio)-4-Oxo-4,5,6,7-Tetrahydro-1H-Cyclopenta[D]Pyrimidin-1-Yl)-N-((4'-(Trifluoromethyl)-[1,1'-Biphenyl]-4-Yl)Methyl)Acetamide 95% 250mg $274 2026-05-28 Buy
aablocks AA003P5Z N-(2-(Diethylamino)Ethyl)-2-(2-((4-Fluorobenzyl)Thio)-4-Oxo-4,5,6,7-Tetrahydro-1H-Cyclopenta[D]Pyrimidin-1-Yl)-N-((4'-(Trifluoromethyl)-[1,1'-Biphenyl]-4-Yl)Methyl)Acetamide 95% 1g $807 2026-05-28 Buy
ACHEMBLOCK C-2941 Darapladib 98% 25MG $100 2026-05-27 Buy
ACHEMBLOCK C-2941 Darapladib 98% 1G $435 2026-05-27 Buy
ACHEMBLOCK C-2941 Darapladib 98% 100MG $260 2026-05-27 Buy
AK Scientific SYN5724 Darapladib 100mg $1660 2021-12-16 Buy
Ambeed A684359 N-(2-(Diethylamino)ethyl)-2-(2-((4-fluorobenzyl)thio)-4-oxo-4,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-1-yl)-N-((4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)methyl)acetamide 98+% 1g $1084 2021-12-16 Buy
Ambeed A684359 N-(2-(Diethylamino)ethyl)-2-(2-((4-fluorobenzyl)thio)-4-oxo-4,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-1-yl)-N-((4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)methyl)acetamide 98+% 100mg $218 2021-12-16 Buy
Ambeed A684359 N-(2-(Diethylamino)ethyl)-2-(2-((4-fluorobenzyl)thio)-4-oxo-4,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-1-yl)-N-((4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)methyl)acetamide 98+% 250mg $434 2021-12-16 Buy
Ambeed A684359 N-(2-(Diethylamino)ethyl)-2-(2-((4-fluorobenzyl)thio)-4-oxo-4,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-1-yl)-N-((4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)methyl)acetamide 98+% 5mg $76 2021-12-16 Buy
Ambeed A684359 N-(2-(Diethylamino)ethyl)-2-(2-((4-fluorobenzyl)thio)-4-oxo-4,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-1-yl)-N-((4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)methyl)acetamide 98+% 10mg $99 2021-12-16 Buy
Ambeed A684359 N-(2-(Diethylamino)ethyl)-2-(2-((4-fluorobenzyl)thio)-4-oxo-4,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-1-yl)-N-((4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)methyl)acetamide 98+% 1mg $43 2021-12-16 Buy
Ambeed A684359 N-(2-(Diethylamino)ethyl)-2-(2-((4-fluorobenzyl)thio)-4-oxo-4,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-1-yl)-N-((4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)methyl)acetamide 98+% 50mg $168 2021-12-16 Buy
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Properties

Boiling point :741.0±70.0 °C(Predicted)
Density :1.25
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :≥32.95 mg/mL in DMSO; insoluble in H2O; ≥891 mg/mL in EtOH
form :solid
pka :9.03±0.10(Predicted)
color :White to off-white
InChIKey :WDPFJWLDPVQCAJ-UHFFFAOYSA-N
SMILES :O=C1N=C(SCC2=CC=C(F)C=C2)N(CC(N(CCN(CC)CC)CC3=CC=C(C4=CC=C(C(F)(F)F)C=C4)C=C3)=O)C5=C1CCC5

Safety Information

Symbol(GHS): Environment (GHS09)Corrosion (GHS05)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning P273, P391, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310 Immediately call a POISON CENTER or doctor/physician.
P391 Collect spillage. Hazardous to the aquatic environment
P501 Dispose of contents/container to..…

Description

Darapladib (SB-480848) is a reversible lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with IC50 of 0.25 nM. Phase 3.

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Suppliers and manufacturers

Shanghai Boyle Chemical Co., Ltd. Chembest Research Laboratories Limited Nanjing Vital Chemical Co., Ltd. Shanghai Sphchem Co., Ltd. Dalian Meilun Biotech Co., Ltd. Haoyuan Chemexpress Co., Ltd. Shanghai Aladdin Bio-Chem Technology Co.,LTD Shanghai Jiyi Biological Technology Co., LTD China Nobel Chem Co., Limited EnliPharma Technology Co., Ltd