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ChemicalBook >> CAS DataBase List >> Z-VAD-FMK

Z-VAD-FMK

Z-VAD-FMK price.
  • $99 - $682
  • Product name: Z-VAD-FMK
  • CAS: 187389-52-2
  • MF: C22H30FN3O7
  • MW: 467.49
  • EINECS:
  • MDL Number:MFCD03452883
  • Synonyms:Z-VADC(OME)-FMK;methyl (3S)-5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-phenylmethoxycarbonylamino-butanoyl]amino]propanoyl]amino]-4-oxo-pentanoate;N-BENZYLOXYCARBONYL-VAL-ALA-ASP FLUOROMETHYL KETONE;Z-VAD-FLUOROMETHYLKETONE;Z-VAD-FMK;Z-VAD-FMK, METHYL ESTER;Z-VAD(OME)-FLUOROMETHYLKETONE;L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-
6 prices
Selected condition:

Brand

  • Cayman Chemical
  • Sigma-Aldrich

Package

  • 1mg
  • 5mg
  • 2 mg
  • 100 μg
  • ManufacturerCayman Chemical
  • Product number14463
  • Product descriptionZ-VAD(OMe)-FMK ≥95%
  • Packaging5mg
  • Price$421
  • Updated2021-03-22
  • Buy
  • ManufacturerCayman Chemical
  • Product number14463
  • Product descriptionZ-VAD(OMe)-FMK ≥95%
  • Packaging1mg
  • Price$99
  • Updated2021-03-22
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number627610
  • Product descriptionCaspase Inhibitor I
  • Packaging1mg
  • Price$249
  • Updated2020-08-18
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSAB2501669
  • Product descriptionAnti-CASP3 antibody produced in goat affinity isolated antibody, buffered aqueous solution
  • Packaging100 μg
  • Price$460
  • Updated2021-03-22
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number627610
  • Product descriptionCaspase Inhibitor I
  • Packaging5mg
  • Price$521
  • Updated2020-08-18
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberV116
  • Product descriptionZ-VAD-FMK solid
  • Packaging2 mg
  • Price$682
  • Updated2021-03-22
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 14463 Z-VAD(OMe)-FMK ≥95% 5mg $421 2021-03-22 Buy
Cayman Chemical 14463 Z-VAD(OMe)-FMK ≥95% 1mg $99 2021-03-22 Buy
Sigma-Aldrich 627610 Caspase Inhibitor I 1mg $249 2020-08-18 Buy
Sigma-Aldrich SAB2501669 Anti-CASP3 antibody produced in goat affinity isolated antibody, buffered aqueous solution 100 μg $460 2021-03-22 Buy
Sigma-Aldrich 627610 Caspase Inhibitor I 5mg $521 2020-08-18 Buy
Sigma-Aldrich V116 Z-VAD-FMK solid 2 mg $682 2021-03-22 Buy

Properties

Boiling point: :732.4±60.0 °C(Predicted)
Density  :1.214±0.06 g/cm3 (20 ºC 760 Torr)
Flash point: :396.7℃
storage temp.  :-20°C
solubility  :DMSO: 20 mg/mL
form  :powder
pka :11.05±0.46(Predicted)
color  :white
InChIKey :MIFGOLAMNLSLGH-QOKNQOGYSA-N
CAS DataBase Reference :187389-52-2

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Z-VAD(OMe)-FMK is a cell-permeable, competitive, and irreversible inhibitor of all caspases. Through this action, it inhibits cleavage of poly(ADP-ribose) polymerase, preventing apoptosis when used at 10-50 μM. It also blocks caspase-mediated apoptosis in vivo. Z-VAD(OMe)-FMK effectively prevents caspase action in inflammasomes.

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