Dapagliflozin
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- $5 - $1504.5
- Product name: Dapagliflozin
- CAS: 461432-26-8
- MF: C21H25ClO6
- MW: 408.88
- EINECS:639-683-0
- MDL Number:MFCD13182359
- Synonyms:Dapagliflozin(BMS-512148);1-[4-Chloro-3-(4-ethoxybenzyl)phenyl]-1-deoxy-beta-D-glucopyranose (1S)-1,5-Anhydro-1-C-[4-chloro-3-(4-ethoxybenzyl)phenyl]-D-glucitol (2S,3R,4R,5S,6R)-2-[4-Chloro-3-(4-ethoxybenzyl)phenyl]-6-(hydroxyMethyl)tetrahydro-2H-pyran-3,4,5-triol;(2S,3R,4R,5S,6R)-2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxyMethyltetrahydro-2H-pyran-3,4,5-triol;1-[4-Chloro-3-(4-ethoxybenzyl)phenyl]-1-deoxy-beta-D-glucopyranose;BMS5121458;Dag coluMn net;Dapagliflozin Isomer Impurity;Dapagliflozin, >=98%
46 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- TRC
- Usbiological
Package
- 1unit
- 10mM(in 1mL DMSO)
- 1mg
- 5mg
- 10mg
- 20mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 2g
- 5g
- 10g
- 25g
- ManufacturerAK Scientific
- Product numberJ95139
- Product descriptionDapagliflozin
- Packaging1g
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ95139
- Product descriptionDapagliflozin
- Packaging10g
- Price$380
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA120381
- Product description(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 97+%
- Packaging5mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA120381
- Product description(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 97+%
- Packaging10mg
- Price$6
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA120381
- Product description(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 97+%
- Packaging50mg
- Price$10
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA120381
- Product description(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 97+%
- Packaging100mg
- Price$17
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA120381
- Product description(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 97+%
- Packaging250mg
- Price$32
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA120381
- Product description(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 97+%
- Packaging1g
- Price$81
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA120381
- Product description(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 97+%
- Packaging5g
- Price$237
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA120381
- Product description(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 97+%
- Packaging10g
- Price$447
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA120381
- Product description(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 97+%
- Packaging25g
- Price$878
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5854
- Product descriptionDapagliflozin
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5854
- Product descriptionDapagliflozin
- Packaging5mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5854
- Product descriptionDapagliflozin
- Packaging10mM(in 1mL DMSO)
- Price$77
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5854
- Product descriptionDapagliflozin
- Packaging25mg
- Price$210
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5854
- Product descriptionDapagliflozin
- Packaging100mg
- Price$450
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | J95139 | Dapagliflozin | 1g | $70 | 2021-12-16 | Buy |
| AK Scientific | J95139 | Dapagliflozin | 10g | $380 | 2021-12-16 | Buy |
| Ambeed | A120381 | (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 97+% | 5mg | $5 | 2021-12-16 | Buy |
| Ambeed | A120381 | (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 97+% | 10mg | $6 | 2021-12-16 | Buy |
| Ambeed | A120381 | (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 97+% | 50mg | $10 | 2021-12-16 | Buy |
| Ambeed | A120381 | (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 97+% | 100mg | $17 | 2021-12-16 | Buy |
| Ambeed | A120381 | (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 97+% | 250mg | $32 | 2021-12-16 | Buy |
| Ambeed | A120381 | (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 97+% | 1g | $81 | 2021-12-16 | Buy |
| Ambeed | A120381 | (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 97+% | 5g | $237 | 2021-12-16 | Buy |
| Ambeed | A120381 | (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 97+% | 10g | $447 | 2021-12-16 | Buy |
| Ambeed | A120381 | (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 97+% | 25g | $878 | 2021-12-16 | Buy |
| ApexBio Technology | A5854 | Dapagliflozin | 1unit | $28 | 2021-12-16 | Buy |
| ApexBio Technology | A5854 | Dapagliflozin | 5mg | $70 | 2021-12-16 | Buy |
| ApexBio Technology | A5854 | Dapagliflozin | 10mM(in 1mL DMSO) | $77 | 2021-12-16 | Buy |
| ApexBio Technology | A5854 | Dapagliflozin | 25mg | $210 | 2021-12-16 | Buy |
| ApexBio Technology | A5854 | Dapagliflozin | 100mg | $450 | 2021-12-16 | Buy |
Properties
Melting point :55-58°C
Boiling point :609.0±55.0 °C(Predicted)
Density :1.349
storage temp. :2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
pka :13.23±0.70(Predicted)
form :Solid
color :White to Pale Yellow
Stability :Hygroscopic
Boiling point :609.0±55.0 °C(Predicted)
Density :1.349
storage temp. :2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
pka :13.23±0.70(Predicted)
form :Solid
color :White to Pale Yellow
Stability :Hygroscopic
Safety Information
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Description
Inhibiting renal glucose reabsorbtion through the sodium-glucose cotransporter (SGLT) offers an insulin-independent alternative to controlling blood glucose concentrations in patients with type 2 diabetes. While the majority of glucose is reabsorbed from glomerular filtrate by SGLT2, which is predominantly expressed in the kidney S1 segment of the proximal tubule, SGLT1 reabsorbs glucose in the distal S3 segment of the renal proximal tubule as well as from the small intestine. Dapagliflozin is a first generation, selective SGLT inhibitor that blocks glucose transport with about 100-fold selectivity for SGLT2 (Ki = 6 nM; EC50 = 1.1 nM) over SGLT1 (Ki = 390 nM). After single oral doses ranging from 0.1 to 1.0 mg/kg, dapagliflozin increases urinary glucose excretion in both normal and diabetic rats, improves glucose tolerance in normal rats, and reduces hyperglycemia in Zucker diabetic fatty rats. Within two weeks of treating diabetic rats with 0.1 to 1.0 mg/kg dapagliflozin, fasting and fed glucose levels have been shown to be significantly lowered as a result of increased glucose utilization accompanied by reduced glucose production.Related product price
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Suppliers and manufacturers
Hangzhou ICH Biofarm Co., Ltd
![(2S,3R,4R,5S,6R)-2-[4-Chloro-3-(4-ethoxybenzyl)phenyl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol](/ProductImageEN/2023-07/small/bbe4e95a-455f-4b91-9103-e8369bb36ee3.png)
Senova Technology Co. Ltd.
Hubei Ipure Biology Co., Ltd
$0.00 /1KG
(2S,3R,4R,5S,6R)-2-[4-Chloro-3-(4-ethoxybenzyl)phenyl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol CAS:461432-26-8
(2S,3R,4R,5S,6R)-2-[4-Chloro-3-(4-ethoxybenzyl)phenyl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol CAS:461432-26-8
