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ChemicalBook >> CAS DataBase List >> Deoxycholic acid

Deoxycholic acid

Deoxycholic acid price.
  • $6 - $1460
  • Product name: Deoxycholic acid
  • CAS: 83-44-3
  • MF: C24H40O4
  • MW: 392.58
  • EINECS:201-478-5
  • MDL Number:MFCD00003673
  • Synonyms:DEOXYCHOLIC ACID;7-DEOXYCHOLIC ACID;5BETA-CHOLAN-3ALPHA, 12BETA-DIOL;5BETA-CHOLAN-24-OIC ACID-3ALPHA,12ALPHA-DIOL;5-BETA-CHOLANIC ACID-3-ALPHA, 12-ALPHA-DIOL;5B-CHOLAN-24-OIC ACID-3A,12A-DIOL;(3alpha,5beta,12alpha)-3,12-dihydroxy-cholan-24-oic acid;3ALPHA,12ALPHA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID
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Brand
  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
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  • Medical Isotopes, Inc.
  • Sigma-Aldrich
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Package
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  • 10mM(in 1mL DMSO)
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  • 5G
  • 25g
  • 500g
  • ManufacturerAK Scientific
  • Product numberH681
  • Product descriptionDeoxycholic acid
  • Packaging100g
  • Price$67
  • Updated2021-12-16
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  • ManufacturerAlfa Aesar
  • Product numberB20061
  • Product descriptionDeoxycholic acid, 99%
  • Packaging25g
  • Price$37.7
  • Updated2023-06-20
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  • ManufacturerAlfa Aesar
  • Product numberB20061
  • Product descriptionDeoxycholic acid, 99%
  • Packaging100g
  • Price$90.7
  • Updated2023-06-20
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  • ManufacturerAlfa Aesar
  • Product numberB20061
  • Product descriptionDeoxycholic acid 99%
  • Packaging500g
  • Price$313
  • Updated2023-06-20
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberSHG0020423
  • Product descriptionDEOXYCHOLIC ACID 95.00%
  • Packaging5MG
  • Price$453.73
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002251
  • Product descriptionDEOXY CHOLIC ACID 95.00%
  • Packaging1G
  • Price$597.87
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002251
  • Product descriptionDEOXY CHOLIC ACID 95.00%
  • Packaging2.5G
  • Price$746.88
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002251
  • Product descriptionDEOXY CHOLIC ACID 95.00%
  • Packaging5G
  • Price$808.96
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN1669
  • Product descriptionDeoxycholic acid
  • Packaging20mg
  • Price$40
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberN1669
  • Product descriptionDeoxycholic acid
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS034611
  • Product descriptionDeoxycholic acid ≥98%
  • Packaging250mg
  • Price$6
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS034611
  • Product descriptionDeoxycholic acid ≥98%
  • Packaging1g
  • Price$13
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberCFN99798
  • Product descriptionDeoxycholic acid ≥98%
  • Packaging20mg
  • Price$30
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS034611
  • Product descriptionDeoxycholic acid ≥98%
  • Packaging5g
  • Price$44
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS034611
  • Product descriptionDeoxycholic acid ≥98%
  • Packaging25g
  • Price$148
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS034611
  • Product descriptionDeoxycholic acid ≥98%
  • Packaging100g
  • Price$485
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific H681 Deoxycholic acid 100g $67 2021-12-16 Buy
Alfa Aesar B20061 Deoxycholic acid, 99% 25g $37.7 2023-06-20 Buy
Alfa Aesar B20061 Deoxycholic acid, 99% 100g $90.7 2023-06-20 Buy
Alfa Aesar B20061 Deoxycholic acid 99% 500g $313 2023-06-20 Buy
American Custom Chemicals Corporation SHG0020423 DEOXYCHOLIC ACID 95.00% 5MG $453.73 2021-12-16 Buy
American Custom Chemicals Corporation API0002251 DEOXY CHOLIC ACID 95.00% 1G $597.87 2021-12-16 Buy
American Custom Chemicals Corporation API0002251 DEOXY CHOLIC ACID 95.00% 2.5G $746.88 2021-12-16 Buy
American Custom Chemicals Corporation API0002251 DEOXY CHOLIC ACID 95.00% 5G $808.96 2021-12-16 Buy
ApexBio Technology N1669 Deoxycholic acid 20mg $40 2021-12-16 Buy
ApexBio Technology N1669 Deoxycholic acid 10mM(in 1mL DMSO) $50 2021-12-16 Buy
Arctom AS034611 Deoxycholic acid ≥98% 250mg $6 2021-12-16 Buy
Arctom AS034611 Deoxycholic acid ≥98% 1g $13 2021-12-16 Buy
Arctom CFN99798 Deoxycholic acid ≥98% 20mg $30 2021-12-16 Buy
Arctom AS034611 Deoxycholic acid ≥98% 5g $44 2021-12-16 Buy
Arctom AS034611 Deoxycholic acid ≥98% 25g $148 2021-12-16 Buy
Arctom AS034611 Deoxycholic acid ≥98% 100g $485 2021-12-16 Buy

Properties

Melting point :171-174 °C(lit.)
Boiling point :437.26°C (rough estimate)
alpha :55 º (c=1, EtOH)
Density :0.9985 (rough estimate)
vapor pressure :0.004Pa at 20℃
refractive index :1.4460 (estimate)
Flash point :9℃
storage temp. :room temp
solubility :0.24 g/L (15°C)
pka :5.15(at 20℃)
form :Solid
color :White to Off-White
optical activity :[α]20/D +54±1°, c = 1% in ethanol
Water Solubility :0.24 g/L (15 ºC)
Merck :14,2899
BRN :3219882
Stability :Stable. Combustible. Incompatible with strong oxidizing agents.
LogP :5.34 at 22℃ and pH5.7
Surface tension :54mN/m at 51.3mg/L and 20℃
CAS DataBase Reference :83-44-3(CAS DataBase Reference)
EPA Substance Registry System :Cholan-24-oic acid, 3,12-dihydroxy-, (3.alpha.,5.beta.,12.alpha.)- (83-44-3)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

Deoxycholic acid (conjugate base deoxycholate), also known as cholanoic acid, Kybella, Celluform Plus and 3α, 12α-dihydroxy-5β-cholan-24-oic acid, is a secondary bile acid produced from cholic acid by bacterial action in the colon. Deoxycholic acid is soluble in alcohol and acetic acid. When pure, it comes in a white to off-white crystalline powder form. It is usually conjugated with glycine or taurine and acts as a detergent in the emulsification of fats for intestinal absorption. In April 2015, deoxycholic acid was approved by the FDA for the treatment submental fat to improve aesthetic appearance and reduce facial fullness or convexity. It is marketed under the brand name Kybella by Kythera Biopharma and is the first pharmacological agent available for submental fat reduction, allowing for a safer and less invasive alternative than surgical procedures. When injected into submental fat, it stimulates a targeted breakdown of adipose cells by disrupting the cell membrane and causing adipocytolysis, resulting in an inflammatory reaction and clearing of the adipose tissue remnants by macrophages. However, deoxycholic acid has not been tested for safe use on other areas of the body. Except for its main use, deoxycholic acid has been used in a study to assess a pH-Responsive Mechanism of a Deoxycholic Acid and Folate Co-Modified Chitosan Micelle under Cancerous Environment. It has also been used in a study to investigate dose-dependent anti-inflammatory effect of ursodeoxycholic acid in experimental colitis.

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