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ChemicalBook >> CAS DataBase List >> Exemestane

Exemestane

Exemestane price.
  • $28 - $1760
  • Product name: Exemestane
  • CAS: 107868-30-4
  • MF: C20H24O2
  • MW: 296.4
  • EINECS:643-090-2
  • MDL Number:MFCD00866994
  • Synonyms:ExeMestane (USP);1,4-Androstadien-3,17-dione-6-Methylene-d2;(8R,9S,10R,13S,14S)-10,13-Dimethyl-6-methylene-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17(10H,14H)-dione;ExeMestine;(8R,9S,10R,13S,14S)-10,13-diMethyl-6-Methylene-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione;ExeMestane SynonyMs 6-Methylenandrosta-1,4-diene-3,17-dione;PNU155971;Exemestane for system suitability
29 prices
Selected condition:
Brand
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • AvaChem
  • Axon Medchem
  • Cayman Chemical
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 25mg
  • 50mg
  • 1g
  • 5g
  • 5mg
  • 10MG
  • 150mg
  • 50
  • 100MG
  • y0001747
  • 10mM(in 1mL DMSO)
  • 10g
  • y0001756
  • ManufacturerAHH
  • Product numberAPI-1298
  • Product descriptionExemestane 98%
  • Packaging10g
  • Price$330
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberH824
  • Product descriptionExemestane
  • Packaging5mg
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberSHG0006419
  • Product descriptionEXEMESTANE 95.00%
  • Packaging5MG
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberSHG0006419
  • Product descriptionEXEMESTANE 95.00%
  • Packaging10MG
  • Price$704.55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberSHG0006419
  • Product descriptionEXEMESTANE 95.00%
  • Packaging100MG
  • Price$1593.9
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1296
  • Product descriptionExemestane
  • Packaging10mM(in 1mL DMSO)
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1712
  • Product descriptionExemestane
  • Packaging25mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1712
  • Product descriptionExemestane
  • Packaging100mg
  • Price$69
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1712
  • Product descriptionExemestane
  • Packaging1g
  • Price$109
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1712
  • Product descriptionExemestane
  • Packaging10g
  • Price$390
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2045
  • Product descriptionExemestane-Aromasin|FCE24304 98%
  • Packaging50mg
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15008
  • Product descriptionExemestane ≥95%
  • Packaging5mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15008
  • Product descriptionExemestane ≥95%
  • Packaging10mg
  • Price$70
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15008
  • Product descriptionExemestane ≥95%
  • Packaging25mg
  • Price$152
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15008
  • Product descriptionExemestane ≥95%
  • Packaging50mg
  • Price$281
  • Updated2024-03-01
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004640
  • Product descriptionExemestane 97%
  • Packaging1g
  • Price$260
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH API-1298 Exemestane 98% 10g $330 2021-12-16 Buy
AK Scientific H824 Exemestane 5mg $28 2021-12-16 Buy
American Custom Chemicals Corporation SHG0006419 EXEMESTANE 95.00% 5MG $550 2021-12-16 Buy
American Custom Chemicals Corporation SHG0006419 EXEMESTANE 95.00% 10MG $704.55 2021-12-16 Buy
American Custom Chemicals Corporation SHG0006419 EXEMESTANE 95.00% 100MG $1593.9 2021-12-16 Buy
ApexBio Technology A1296 Exemestane 10mM(in 1mL DMSO) $60 2021-12-16 Buy
AvaChem 1712 Exemestane 25mg $39 2021-12-16 Buy
AvaChem 1712 Exemestane 100mg $69 2021-12-16 Buy
AvaChem 1712 Exemestane 1g $109 2021-12-16 Buy
AvaChem 1712 Exemestane 10g $390 2021-12-16 Buy
Axon Medchem Axon2045 Exemestane-Aromasin|FCE24304 98% 50mg $220 2021-12-16 Buy
Cayman Chemical 15008 Exemestane ≥95% 5mg $44 2024-03-01 Buy
Cayman Chemical 15008 Exemestane ≥95% 10mg $70 2024-03-01 Buy
Cayman Chemical 15008 Exemestane ≥95% 25mg $152 2024-03-01 Buy
Cayman Chemical 15008 Exemestane ≥95% 50mg $281 2024-03-01 Buy
Crysdot CD31004640 Exemestane 97% 1g $260 2021-12-16 Buy

Properties

Melting point :155.13°C
Boiling point :453.7±45.0 °C(Predicted)
Density :1.13±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥20mg/mL
form :powder
color :white to off-white
optical activity :[α]/D +250 to +300°, c = 1 in methanol
InChI :InChI=1S/C20H24O2/c1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h6,8,11,14-16H,1,4-5,7,9-10H2,2-3H3/t14-,15-,16-,19+,20-/m0/s1
InChIKey :BFYIZQONLCFLEV-DAELLWKTSA-N
SMILES :C1(=O)C=C2[C@](C)(C=C1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)C(=O)CC3)CC2=C
CAS DataBase Reference :107868-30-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P391 Collect spillage. Hazardous to the aquatic environment

Description

Exemestane is a third generation, irreversible steroidal aromatase inhibitor (Ki = 10.2 nM; Kinact = 26 nM) that induces aromatase degradation leading to a decrease in estrogen levels in plasma. As an androgen analog, exemestane exhibits androgenic effects and has been shown to decrease total and HDL cholesterol, apo A1, and total triglyceride levels. Marketed under the trade name Aromasin?, exemestane has been used to treat estrogen receptor-positive breast cancers in post-menopausal women.

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