GSK J1
|
- $70 - $1800
- Product name: GSK J1
- CAS: 1373422-53-7
- MF: C22H23N5O2
- MW: 389.45
- EINECS:200-258-5
- MDL Number:MFCD22683851
- Synonyms:GSK J1;GSK-J1;N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-beta-alanine;GCK J1;3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(pyridin-2-yl)pyrimidin-4-yl)amino)propanoic acid;N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyriMidinyl]-|-alanine;Histone Lysine Demethylase Inhibitor VII, GSK-J1 ;Histone Lysine Demethylase Inhibitor VII, GSK-J1 - CAS 1373422-53-7 - Calbiochem
20 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Biorbyt Ltd
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 5mg
- 10mg
- 10
- 2x5mg
- 25mg
- 50mg
- 50
- 100mg
- 200mg
- 1g
- ManufacturerAdipogen Life Sciences
- Product numberSYN-3030-M100
- Product descriptionGSK-J1 ≥95%
- Packaging100mg
- Price$1026
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN3030
- Product descriptionGSK-J1
- Packaging5mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0009880
- Product descriptionGSK-J1 95.00%
- Packaging5MG
- Price$502.98
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4191
- Product descriptionGSKJ1
- Packaging200mg
- Price$665
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1934
- Product descriptionGSKJ1 99%
- Packaging2x5mg
- Price$176
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545893
- Product descriptionGSK-J1 >98%
- Packaging5mg
- Price$198.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545893
- Product descriptionGSK-J1 >98%
- Packaging25mg
- Price$554.2
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM161403
- Product description3-((2-(pyridin-2-yl)-6-(1,2,4,5-tetrahydro-3H-benzo[d]azepin-3-yl)pyrimidin-4-yl)amino)propanoicacid 98%
- Packaging50mg
- Price$203
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3322
- Product descriptionGSK-J1 99.98%
- Packaging10mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3322
- Product descriptionGSK-J1 99.98%
- Packaging25mg
- Price$115
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3322
- Product descriptionGSK-J1 99.98%
- Packaging50mg
- Price$205
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3322
- Product descriptionGSK-J1 99.98%
- Packaging100mg
- Price$340
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31003707
- Product descriptionGSK-J1 98+%
- Packaging50mg
- Price$291
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7858
- Product descriptionHistonedemethylaseinhibitorJ1 >98%
- Packaging1g
- Price$1800
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML0709
- Product descriptionGSK-J1 ≥98% (HPLC)
- Packaging5mg
- Price$78
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML0709
- Product descriptionGSK-J1 ≥98% (HPLC)
- Packaging25mg
- Price$191.2
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | SYN-3030-M100 | GSK-J1 ≥95% | 100mg | $1026 | 2021-12-16 | Buy |
| AK Scientific | SYN3030 | GSK-J1 | 5mg | $110 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0009880 | GSK-J1 95.00% | 5MG | $502.98 | 2021-12-16 | Buy |
| ApexBio Technology | A4191 | GSKJ1 | 200mg | $665 | 2021-12-16 | Buy |
| Axon Medchem | Axon1934 | GSKJ1 99% | 2x5mg | $176 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb545893 | GSK-J1 >98% | 5mg | $198.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb545893 | GSK-J1 >98% | 25mg | $554.2 | 2021-12-16 | Buy |
| Chemenu | CM161403 | 3-((2-(pyridin-2-yl)-6-(1,2,4,5-tetrahydro-3H-benzo[d]azepin-3-yl)pyrimidin-4-yl)amino)propanoicacid 98% | 50mg | $203 | 2021-12-16 | Buy |
| ChemScene | CS-3322 | GSK-J1 99.98% | 10mg | $70 | 2021-12-16 | Buy |
| ChemScene | CS-3322 | GSK-J1 99.98% | 25mg | $115 | 2021-12-16 | Buy |
| ChemScene | CS-3322 | GSK-J1 99.98% | 50mg | $205 | 2021-12-16 | Buy |
| ChemScene | CS-3322 | GSK-J1 99.98% | 100mg | $340 | 2021-12-16 | Buy |
| Crysdot | CD31003707 | GSK-J1 98+% | 50mg | $291 | 2021-12-16 | Buy |
| DC Chemicals | DC7858 | HistonedemethylaseinhibitorJ1 >98% | 1g | $1800 | 2021-12-16 | Buy |
| Sigma-Aldrich | SML0709 | GSK-J1 ≥98% (HPLC) | 5mg | $78 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0709 | GSK-J1 ≥98% (HPLC) | 25mg | $191.2 | 2024-03-01 | Buy |
Properties
Boiling point :608.9±55.0 °C(Predicted)
Density :1.292±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble15mg/mL, clear
form :powder
pka :4.20±0.10(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase? as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChIKey :AVZCPICCWKMZDT-UHFFFAOYSA-N
Density :1.292±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble15mg/mL, clear
form :powder
pka :4.20±0.10(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase? as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChIKey :AVZCPICCWKMZDT-UHFFFAOYSA-N
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
GSK-J1 (1373422-53-7) is a potent and selective inhibitor of jumonji H3K27 histone demethylases JMJD3 and UTX (IC50 = 60 nM, human JMJD3). This is the first known inhibitor selective for the H3K27me3-specific JMJ subfamily which binds to the active catalytic site of the enzyme. The COOH group confers cell impermeability and as such GSK-J1 is useful as a standard in in vitro assays. A cell permeable ethyl ester analog is also available, see GSK-J4 (cat.# 10-1394).More related product prices
GSK J2 GSK J5 GSK J4 HCl 101574-65-6 Selonsertib 1014691-61-2 GS967 GS9620 Entospletinib (GS-9973) 2-Cyanopyridine Entinostat 96017-59-3 Resveratrol SIRTINOLRelated product price
- GSK J2
$85-750 - GSK J5
$146-1962 - GSK J4 HCl
$110-1962
