Selonsertib
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- $12 - $2841
- Product name: Selonsertib
- CAS: 1448428-04-3
- MF: C24H24FN7O
- MW: 445.49
- EINECS:
- MDL Number:MFCD29920355
- Synonyms:Selonsertib;5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]benzamide;Selonsertib GS-4997;GS-4497;GS-4997;ASK-1;GS4997 SELONSERTIB;5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-4-methylbenzamide;Benzamide, 5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]-
88 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Ark Pharm
- Axon Medchem
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- TRC
Package
- 500μg
- 0.005g
- 0.01g
- 0.025g
- 100.00mg
- 0.1g
- 0.05g
- 10mM*1mLinDMSO(Solution)
- 1.00g
- 10mM*1mLinDMSO
- 250.00mg
- 1mg
- 10mM(1mLinDMSO)
- 5mg
- 10mg
- 25MG
- 50mg
- 100mg
- 200mg
- 1g
- 10mM*1mLinDMSO(Solid+Solvent)
- 250mg
- Manufactureraablocks
- Product numberAA00ABQH
- Product description5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]benzamide 97%
- Packaging1mg
- Price$12
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABQH
- Product description5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]benzamide 97%
- Packaging5mg
- Price$14
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABQH
- Product description5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]benzamide 97%
- Packaging10mg
- Price$17
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABQH
- Product description5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]benzamide 97%
- Packaging100mg
- Price$49
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABQH
- Product description5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]benzamide 97%
- Packaging250mg
- Price$78
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABQH
- Product description5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]benzamide 97%
- Packaging1g
- Price$296
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberM15697
- Product descriptionSelonsertib 98%
- Packaging25MG
- Price$40
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberM15697
- Product descriptionSelonsertib 98%
- Packaging100MG
- Price$100
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberM15697
- Product descriptionSelonsertib 98%
- Packaging1G
- Price$250
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1231-M001
- Product descriptionSelonsertib (free base) ≥95%
- Packaging1mg
- Price$97
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1231-M005
- Product descriptionSelonsertib(freebase) ≥95%
- Packaging5mg
- Price$205
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1231-M010
- Product descriptionSelonsertib(freebase) ≥95%
- Packaging10mg
- Price$313
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1231-M100
- Product descriptionSelonsertib(freebase) ≥95%
- Packaging100mg
- Price$1609
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1231-M005
- Product descriptionSelonsertib (free base) ≥95%
- Packaging5mg
- Price$205
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1231-M010
- Product descriptionSelonsertib (free base) ≥95%
- Packaging10mg
- Price$313
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1231-M050
- Product descriptionSelonsertib (free base) ≥95%
- Packaging50mg
- Price$961
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00ABQH | 5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]benzamide 97% | 1mg | $12 | 2026-05-28 | Buy |
| aablocks | AA00ABQH | 5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]benzamide 97% | 5mg | $14 | 2026-05-28 | Buy |
| aablocks | AA00ABQH | 5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]benzamide 97% | 10mg | $17 | 2026-05-28 | Buy |
| aablocks | AA00ABQH | 5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]benzamide 97% | 100mg | $49 | 2026-05-28 | Buy |
| aablocks | AA00ABQH | 5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]benzamide 97% | 250mg | $78 | 2026-05-28 | Buy |
| aablocks | AA00ABQH | 5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]benzamide 97% | 1g | $296 | 2026-05-28 | Buy |
| ACHEMBLOCK | M15697 | Selonsertib 98% | 25MG | $40 | 2026-05-27 | Buy |
| ACHEMBLOCK | M15697 | Selonsertib 98% | 100MG | $100 | 2026-05-27 | Buy |
| ACHEMBLOCK | M15697 | Selonsertib 98% | 1G | $250 | 2026-05-27 | Buy |
| Adipogen Life Sciences | SYN-1231-M001 | Selonsertib (free base) ≥95% | 1mg | $97 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1231-M005 | Selonsertib(freebase) ≥95% | 5mg | $205 | 2021-12-16 | Buy |
| Adipogen Life Sciences | SYN-1231-M010 | Selonsertib(freebase) ≥95% | 10mg | $313 | 2021-12-16 | Buy |
| Adipogen Life Sciences | SYN-1231-M100 | Selonsertib(freebase) ≥95% | 100mg | $1609 | 2021-12-16 | Buy |
| Adipogen Life Sciences | SYN-1231-M005 | Selonsertib (free base) ≥95% | 5mg | $205 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1231-M010 | Selonsertib (free base) ≥95% | 10mg | $313 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1231-M050 | Selonsertib (free base) ≥95% | 50mg | $961 | 2026-05-06 | Buy |
Properties
Melting point :>180°C (dec.)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (>25 mg/ml)
pka :11.21±0.70(Predicted)
form :solid
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :YIDDLAAKOYYGJG-UHFFFAOYSA-N
SMILES :C(NC1=NC(C2N(C(C)C)C=NN=2)=CC=C1)(=O)C1=CC(N2C=NC(C3CC3)=C2)=C(C)C=C1F
CAS DataBase Reference :1448428-04-3
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (>25 mg/ml)
pka :11.21±0.70(Predicted)
form :solid
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :YIDDLAAKOYYGJG-UHFFFAOYSA-N
SMILES :C(NC1=NC(C2N(C(C)C)C=NN=2)=CC=C1)(=O)C1=CC(N2C=NC(C3CC3)=C2)=C(C)C=C1F
CAS DataBase Reference :1448428-04-3
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||
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Description
Selonsertib (1448428-04-3) is a potent Apoptosis signal-regulating kinase 1 (ASK1) inhibitor (pIC50 = 8.3)1 found to improve metabolic parameters in nonalcoholic steatohepatitis, reduce hepatic steatosis, inflammation, and fibrosis2-4. Selonsertib suppressed the efflux function of multidrug resistance (MDR) transporters ABCB1 and ABCG2.5Related product price
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