Gefitinib
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- $5 - $1191
- Product name: Gefitinib
- CAS: 184475-35-2
- MF: C22H24ClFN4O3
- MW: 446.9
- EINECS:643-034-7
- MDL Number:MFCD04307832
- Synonyms:N-(3-Chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine Gefitinib;Gefitinib, >=99%;GEFITINIB RELATED COMPOUND;Gefitinib N-(3-Chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine;GEFITINIB;n-(3-chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine;ZD 1839;4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-
146 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- ApexBio Technology
- Apolloscientific
- Arctom
- AstaTech
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 1mg
- 1unit
- 5mg
- 10mg
- 10mM*1mLinDMSO
- 20mg
- 50
- 25mg
- 100mg
- 250mg
- 50mg
- 10
- Y0001813
- EvaluationSample
- 500mg
- 1g
- 2g
- 5g
- 10g
- 10.00g
- 25g
- 25.00g
- 50g
- 100.00g
- 10mM(in 1mL DMSO)
- 100g
- 250G
- 5/ G
- 25/ G
- 100/ G
- 100 mg
- 351 μg
- 10mM(in1mLDMSO)
- 110 mg
- Manufactureraablocks
- Product numberAA0039I6
- Product descriptionN-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine 98%
- Packaging250mg
- Price$5
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0039I6
- Product descriptionN-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine 98%
- Packaging1g
- Price$8
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0039I6
- Product descriptionN-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine 98%
- Packaging5g
- Price$21
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0039I6
- Product descriptionN-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine 98%
- Packaging10g
- Price$32
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product number10496
- Product descriptionGefitinib 98%
- Packaging1G
- Price$10
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1042-M005
- Product descriptionGefitinib ≥95%
- Packaging5mg
- Price$59
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1042-M001
- Product descriptionGefitinib ≥95%
- Packaging1mg
- Price$43
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1042-M005
- Product descriptionGefitinib ≥95%
- Packaging5mg
- Price$59
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1042-M010
- Product descriptionGefitinib ≥95%
- Packaging10mg
- Price$70
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1042-M050
- Product descriptionGefitinib ≥95%
- Packaging50mg
- Price$130
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1042-M100
- Product descriptionGefitinib ≥95%
- Packaging100mg
- Price$216
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product numberH018
- Product descriptionGefitinib 98%(HPLC)
- Packaging25g
- Price$141
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ94474
- Product descriptionGefitinib 95%
- Packaging25g
- Price$105
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ94474
- Product descriptionGefitinib 95%
- Packaging100g
- Price$305
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberH018
- Product descriptionGefitinib
- Packaging100g
- Price$427
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberH018
- Product descriptionGefitinib 98%(HPLC)
- Packaging100g
- Price$409
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0039I6 | N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine 98% | 250mg | $5 | 2026-05-28 | Buy |
| aablocks | AA0039I6 | N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine 98% | 1g | $8 | 2026-05-28 | Buy |
| aablocks | AA0039I6 | N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine 98% | 5g | $21 | 2026-05-28 | Buy |
| aablocks | AA0039I6 | N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine 98% | 10g | $32 | 2026-05-28 | Buy |
| ACHEMBLOCK | 10496 | Gefitinib 98% | 1G | $10 | 2026-05-27 | Buy |
| Adipogen Life Sciences | SYN-1042-M005 | Gefitinib ≥95% | 5mg | $59 | 2021-12-16 | Buy |
| Adipogen Life Sciences | SYN-1042-M001 | Gefitinib ≥95% | 1mg | $43 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1042-M005 | Gefitinib ≥95% | 5mg | $59 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1042-M010 | Gefitinib ≥95% | 10mg | $70 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1042-M050 | Gefitinib ≥95% | 50mg | $130 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1042-M100 | Gefitinib ≥95% | 100mg | $216 | 2026-05-06 | Buy |
| AK Scientific | H018 | Gefitinib 98%(HPLC) | 25g | $141 | 2026-06-04 | Buy |
| AK Scientific | J94474 | Gefitinib 95% | 25g | $105 | 2026-06-04 | Buy |
| AK Scientific | J94474 | Gefitinib 95% | 100g | $305 | 2026-06-04 | Buy |
| AK Scientific | H018 | Gefitinib | 100g | $427 | 2021-12-16 | Buy |
| AK Scientific | H018 | Gefitinib 98%(HPLC) | 100g | $409 | 2026-06-04 | Buy |
Properties
Melting point :119-1200C
Boiling point :586.8±50.0 °C(Predicted)
Density :1.322±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 4 mg/ml).
pka :7.00±0.10(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChI :InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)
InChIKey :XGALLCVXEZPNRQ-UHFFFAOYSA-N
SMILES :N1=C2C(C=C(OCCCN3CCOCC3)C(OC)=C2)=C(NC2=CC=C(F)C(Cl)=C2)N=C1
CAS DataBase Reference :184475-35-2(CAS DataBase Reference)
Boiling point :586.8±50.0 °C(Predicted)
Density :1.322±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 4 mg/ml).
pka :7.00±0.10(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChI :InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)
InChIKey :XGALLCVXEZPNRQ-UHFFFAOYSA-N
SMILES :N1=C2C(C=C(OCCCN3CCOCC3)C(OC)=C2)=C(NC2=CC=C(F)C(Cl)=C2)N=C1
CAS DataBase Reference :184475-35-2(CAS DataBase Reference)
Safety Information
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Description
Overactivity of the epidermal growth factor receptor-associated tyrosine kinase (EGFR-TK) has been associated with a number of cancers and thus TK inhibitors could be potential therapeutic agents to prevent malignant growth. Gefitinib is a selective EGFR-TK inhibitor that blocks the growth of GEO colon cancer, ZR-75-1 and MCF-10A Ha-ras breast cancer, and OVCAR-3 ovarian cancer cell lines with IC50s ranging between 0.2-0.4 μM. By interfering with the intracellular kinase domain, gefitinib prevents EGFR autophosphorylation and prevents downstream signal transduction. Gefitinib has been used to treat advanced (or recurrent) non-small cell lung cancer. However, the FDA retracted its general approval for this compound (Iressa?) when a phase III trial failed to demonstrate an overall survival benefit. Gefitinib appears to be most efficacious in treating certain EGFR gene mutations that are prevalent in Asian populations.More related product prices
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Suppliers and manufacturers
Yangzhou Qinyuan Pharmatech Co.,ltd
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shandong perfect biotechnology co.ltd
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Hangzhou Hyper Chemicals Limited
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Shaanxi TNJONE Pharmaceutical Co., Ltd
AFINE CHEMICALS LIMITED
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