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ChemicalBook >> CAS DataBase List >> LAS191859

LAS191859

LAS191859 price.
  • $174 - $1733
  • Product name: LAS191859
  • CAS: 1420071-13-1
  • MF: C24H24F3N3O3
  • MW: 459.46
  • EINECS:
  • MDL Number:
  • Synonyms:LAS191859;1H-Pyrrolo[2,3-b]pyridine-3-acetic acid, 1-[2-[[(cyclopropylcarbonyl)ethylamino]methyl]-4-(trifluoromethyl)phenyl]-6-methyl-;1-[2-[[(cyclopropylcarbonyl)ethylamino]methyl]-4-(trifluoromethyl)phenyl]-6-methyl-1H-pyrrolo[2,3-b]pyridine-3-aceticacid
Price7 Properties Safety Information Description
7 prices
Selected condition：
Brand
  • aablocks
  • AK Scientific
  • Cayman Chemical
  • ChemScene
Package
  • 500μg
  • 1mg
  • 5mg
  • 10mg
  • Manufactureraablocks
  • Product numberAA01EPS8
  • Product descriptionLAS191859 ≥98%
  • Packaging1mg
  • Price$312
  • Updated2026-05-30
  • Buy
  • ManufacturerAK Scientific
  • Product number2632DU
  • Product description2-[1-[2-[[Cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]aceticacid
  • Packaging1mg
  • Price$413
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number20238
  • Product descriptionLAS191859 ≥98%
  • Packaging500μg
  • Price$174
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number20238
  • Product descriptionLAS191859 ≥98%
  • Packaging1mg
  • Price$312
  • Updated2026-04-30
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0083787
  • Product descriptionLAS191859
  • Packaging1mg
  • Price$379
  • Updated2026-06-04
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0083787
  • Product descriptionLAS191859
  • Packaging5mg
  • Price$1083
  • Updated2026-06-04
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0083787
  • Product descriptionLAS191859
  • Packaging10mg
  • Price$1733
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA01EPS8 LAS191859 ≥98% 1mg $312 2026-05-30 Buy
AK Scientific 2632DU 2-[1-[2-[[Cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]aceticacid 1mg $413 2021-12-16 Buy
Cayman Chemical 20238 LAS191859 ≥98% 500μg $174 2026-04-30 Buy
Cayman Chemical 20238 LAS191859 ≥98% 1mg $312 2026-04-30 Buy
ChemScene CS-0083787 LAS191859 1mg $379 2026-06-04 Buy
ChemScene CS-0083787 LAS191859 5mg $1083 2026-06-04 Buy
ChemScene CS-0083787 LAS191859 10mg $1733 2026-06-04 Buy

Properties

storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml; Ethanol: 2.5 mg/ml
form :A crystalline solid

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

LAS191859 is a CRTH2/DP2 antagonist with IC50 values of 9.58, 14, 15.5, and 7.6 nM for recombinant human, rat, mouse, and guinea pig CRTH2/DP2 receptors, respectively. In vitro evidence in GTPγS binding studies indicate that LAS191859 is a CRTh2 antagonist with activity in the low nanomolar range. This potency is also maintained in cellular assays performed with human eosinophils and whole blood. The main differentiation of LAS191859 vs other CRTh2 antagonists is in its receptor binding kinetics. LAS191859 has a residence time half-life of 21h at CRTh2 that translates into a long-lasting in vivo efficacy that is independent of plasma levels

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Suppliers and manufacturers

TargetMol Chemicals Inc.
LAS191859
$983.00
LAS191859 CAS:1420071-13-1
BOC Sciences Shanghai Hongye Biotechnology Co. Ltd ChemeGen(Shanghai) Biotechnology Co.,Ltd. TargetMol Chemicals Inc. Shanghai Yifei Biotechnology Co. , Ltd. Guangzhou Ruidi Biotechnology Co., Ltd.