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ChemicalBook >> CAS DataBase List >> LE 300

LE 300

LE 300 price.
  • $36 - $721.59
  • Product name: LE 300
  • CAS: 274694-98-3
  • MF: C20H22N2
  • MW: 290.4
  • EINECS:
  • MDL Number:MFCD00951284
  • Synonyms:7-METHYL-6,7,8,9,14,15-HEXAHYDRO-5H-BENZ[D]INDOLO[2,3-G]AZECINE;6,7,8,9,14,15-HEXAHYDRO-7-METHYL-5H-INDOLO[3,2-F][3]BENZAZECINE;6,7,8,9,14,15-Hexahydro-7-methyl-5H-indolo[3,2-f]benzazecine;LE 300;5H-Indolo[3,2-f][3]benzazecine, 6,7,8,9,14,15-hexahydro-7-methyl-
Price10 Properties Safety Information Description
10 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 5mg
  • 10
  • 1mg
  • 10MG
  • ManufacturerAK Scientific
  • Product number6202CM
  • Product description7-Methyl-6,7,8,9,14,15-hexahydro-5H-benz[d]indolo[2,3-g]azecine
  • Packaging5mg
  • Price$209
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008482
  • Product descriptionLE 300 95.00%
  • Packaging5MG
  • Price$223.3
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008482
  • Product descriptionLE 300 95.00%
  • Packaging10MG
  • Price$721.59
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6824
  • Product descriptionLE300
  • Packaging10mg
  • Price$329
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number29856
  • Product descriptionLE300
  • Packaging1mg
  • Price$36
  • Updated2023-06-20
  • Buy
  • ManufacturerCayman Chemical
  • Product number29856
  • Product descriptionLE300
  • Packaging5mg
  • Price$96
  • Updated2023-06-20
  • Buy
  • ManufacturerCayman Chemical
  • Product number29856
  • Product descriptionLE300 ≥98%
  • Packaging10mg
  • Price$174
  • Updated2023-06-20
  • Buy
  • ManufacturerTocris
  • Product number1674
  • Product descriptionLE300 ≥98%(HPLC)
  • Packaging10
  • Price$227
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberL321003
  • Product descriptionLE300
  • Packaging10mg
  • Price$215
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number255672
  • Product descriptionLE 300
  • Packaging10mg
  • Price$480
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 6202CM 7-Methyl-6,7,8,9,14,15-hexahydro-5H-benz[d]indolo[2,3-g]azecine 5mg $209 2021-12-16 Buy
American Custom Chemicals Corporation API0008482 LE 300 95.00% 5MG $223.3 2021-12-16 Buy
American Custom Chemicals Corporation API0008482 LE 300 95.00% 10MG $721.59 2021-12-16 Buy
ApexBio Technology B6824 LE300 10mg $329 2021-12-16 Buy
Cayman Chemical 29856 LE300 1mg $36 2023-06-20 Buy
Cayman Chemical 29856 LE300 5mg $96 2023-06-20 Buy
Cayman Chemical 29856 LE300 ≥98% 10mg $174 2023-06-20 Buy
Tocris 1674 LE300 ≥98%(HPLC) 10 $227 2021-12-16 Buy
TRC L321003 LE300 10mg $215 2021-12-16 Buy
Usbiological 255672 LE 300 10mg $480 2021-12-16 Buy

Properties

Melting point :>91°C (dec.)
storage temp. :Store at RT
solubility :DMSO: 26 mg/mL
form :solid
color :Off-White to Pale Beige
Stability :Hygroscopic

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

LE300 is a dopamine D1-like receptor antagonist (Kis = 1.9 and 7.5 nM in CHO cell membranes expressing human dopamine D1 and D5 receptors, respectively) and antagonist of the serotonin (5-HT) receptor subtype 5-HT2A (pA2 = 8.32 in a rat tail artery assay). It is selective for dopamine D1 and D5 over D2L and D4.4 receptors (Kis = 44.7 and 109 nM, respectively). LE300 inhibits the conditioned avoidance response in the pole-jump test in rats (ED50 = 0.94 mg/kg), which is predictive for antipsychotic-like activity. It also reduces locomotor activity in the open field test in rats (ED50 = 0.74 mg/kg).

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Suppliers and manufacturers

TargetMol Chemicals Inc.
Wuhan Topule Biopharmaceutical Co., Ltd
Aladdin Scientific 3B Pharmachem (Wuhan) International Co.,Ltd. EMMX Biotechnology LLC Shanghai EFE Biological Technology Co., Ltd. Shanghai Han-Xiang Chemical Co., Ltd. BOC Sciences ChemeGen(Shanghai) Biotechnology Co.,Ltd. MedBioPharmaceutical Technology Inc