Midostaurin
|
- $22 - $2700
- Product name: Midostaurin
- CAS: 120685-11-2
- MF: C35H30N4O4
- MW: 570.64
- EINECS:999-999-2
- MDL Number:MFCD10687105
- Synonyms:CGP 41251MIDOSTAURIN(PKC412);N-((5S,6R,7R,9R)-6-Methoxy-14-oxo-5,6,7,8,9,14,15,16-octahydro-17-oxa-4b,9a,15-triaza-5,9-Methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-7-yl)-N-MethylbenzaMide;PKC-412, CGP-41251;Midostaurin (PKC412);PKC412 (Midostaurin);CGP 41231;N-Benzoylstaurosporine;(Midostaurin) Benzoylstaurosporine
39 prices
Selected condition：
Brand
- AK Scientific
- Alfa Aesar
- Ambeed
- ApexBio Technology
- Apolloscientific
- Arctom
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number3850AH
- Product descriptionMidostaurin hydrate
- Packaging50mg
- Price$651
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ62917
- Product descriptionMidostaurin
- Packaging1mg
- Price$119
- Updated2023-06-20
- Buy
- ManufacturerAlfa Aesar
- Product numberJ62917
- Product descriptionMidostaurin
- Packaging5mg
- Price$424
- Updated2023-06-20
- Buy
- ManufacturerAmbeed
- Product numberA297057
- Product descriptionPKC412 99%
- Packaging1mg
- Price$22
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA297057
- Product descriptionPKC412 99%
- Packaging5mg
- Price$51
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA297057
- Product descriptionPKC412 99%
- Packaging25mg
- Price$115
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA297057
- Product descriptionPKC412 99%
- Packaging50mg
- Price$170
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA297057
- Product descriptionPKC412 99%
- Packaging100mg
- Price$275
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA297057
- Product descriptionPKC412 99%
- Packaging1g
- Price$1420
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3709
- Product descriptionMidostaurin(PKC412)
- Packaging1mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3709
- Product descriptionMidostaurin(PKC412)
- Packaging5mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3709
- Product descriptionMidostaurin(PKC412)
- Packaging10mg
- Price$210
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3709
- Product descriptionMidostaurin(PKC412)
- Packaging25mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIP1007
- Product descriptionPKC412
- Packaging1mg
- Price$219
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIP1007
- Product descriptionPKC412
- Packaging5mg
- Price$715
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIP1007
- Product descriptionPKC412
- Packaging10mg
- Price$1248
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3850AH | Midostaurin hydrate | 50mg | $651 | 2021-12-16 | Buy |
| Alfa Aesar | J62917 | Midostaurin | 1mg | $119 | 2023-06-20 | Buy |
| Alfa Aesar | J62917 | Midostaurin | 5mg | $424 | 2023-06-20 | Buy |
| Ambeed | A297057 | PKC412 99% | 1mg | $22 | 2021-12-16 | Buy |
| Ambeed | A297057 | PKC412 99% | 5mg | $51 | 2021-12-16 | Buy |
| Ambeed | A297057 | PKC412 99% | 25mg | $115 | 2021-12-16 | Buy |
| Ambeed | A297057 | PKC412 99% | 50mg | $170 | 2021-12-16 | Buy |
| Ambeed | A297057 | PKC412 99% | 100mg | $275 | 2021-12-16 | Buy |
| Ambeed | A297057 | PKC412 99% | 1g | $1420 | 2021-12-16 | Buy |
| ApexBio Technology | B3709 | Midostaurin(PKC412) | 1mg | $50 | 2021-12-16 | Buy |
| ApexBio Technology | B3709 | Midostaurin(PKC412) | 5mg | $135 | 2021-12-16 | Buy |
| ApexBio Technology | B3709 | Midostaurin(PKC412) | 10mg | $210 | 2021-12-16 | Buy |
| ApexBio Technology | B3709 | Midostaurin(PKC412) | 25mg | $420 | 2021-12-16 | Buy |
| Apolloscientific | BIP1007 | PKC412 | 1mg | $219 | 2021-12-16 | Buy |
| Apolloscientific | BIP1007 | PKC412 | 5mg | $715 | 2021-12-16 | Buy |
| Apolloscientific | BIP1007 | PKC412 | 10mg | $1248 | 2021-12-16 | Buy |
Properties
Melting point :235-260℃
Density :1.47±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO (15 mg/ml), MDC (10 mg/ml), methanol (5 mg/ml), 100% ethanol (2.5 mg/ml), and DMF (20 mg/ml).
pka :14.19±0.70(Predicted)
form :Tan solid
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
Density :1.47±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO (15 mg/ml), MDC (10 mg/ml), methanol (5 mg/ml), 100% ethanol (2.5 mg/ml), and DMF (20 mg/ml).
pka :14.19±0.70(Predicted)
form :Tan solid
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
Safety Information
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| Signal word: | Danger | ||||||||||||
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Description
PKC 412 is a cell-permeable, reversible inhibitor of several serine/threonine and tyrosine kinases, including conventional PKC isoforms (α, β, and γ), Syk, FLK1, Akt, PKA, c-Kit, C-Fgr, c-Src, FLT3, PDFRβ, VEGFR1, and VEGFR2 with IC50 values ranging from 80-500 nM. It also upregulates the expression of endothelial nitric oxide synthase (eNOS) in mice. PKC 412 inhibits growth or induces apoptosis in many cancer cell types, blocks angiogenesis in tumors, and sensitizes cancer cells to ionizing radiation, supporting its use in cancer therapy.Related product price
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