NSC764414
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- $48 - $1900
- Product name: NSC764414
- CAS: 321695-57-2
- MF: C15H15NO5S
- MW: 321.35
- EINECS:
- MDL Number:
- Synonyms:4-[O-[(4-Methoxyphenyl)sulfonyl]oxime]-2,6-dimethyl-2,5-cyclohexadiene-1,4-dione;L002;NSC764414;p300/CBP Inhibitor VI, L002 ;[(3,5-dimethyl-4-oxo-cyclohexa-2,5-dien-1-ylidene)amino] 4-methoxybenzenesulfonate;L002(NSC764414);L 002;NSC 764414;L-002;NSC-764414;p300/CBP Inhibitor VI, L002 - CAS 321695-57-2 - Calbiochem
58 prices
Selected condition：
Brand
- aablocks
- AK Scientific
- ApexBio Technology
- Axon Medchem
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO
- 5mg
- 10
- 2mg
- 50
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- Manufactureraablocks
- Product numberAA00CNEM
- Product description4-((((4-Methoxyphenyl)sulfonyl)oxy)imino)-2,6-dimethylcyclohexa-2,5-dien-1-one
- Packaging10mg
- Price$85
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00CNEM
- Product description4-((((4-Methoxyphenyl)sulfonyl)oxy)imino)-2,6-dimethylcyclohexa-2,5-dien-1-one
- Packaging25mg
- Price$164
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00CNEM
- Product description4-((((4-Methoxyphenyl)sulfonyl)oxy)imino)-2,6-dimethylcyclohexa-2,5-dien-1-one
- Packaging50mg
- Price$295
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00CNEM
- Product description4-((((4-Methoxyphenyl)sulfonyl)oxy)imino)-2,6-dimethylcyclohexa-2,5-dien-1-one
- Packaging100mg
- Price$474
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00CNEM
- Product description4-((((4-Methoxyphenyl)sulfonyl)oxy)imino)-2,6-dimethylcyclohexa-2,5-dien-1-one
- Packaging5mg
- Price$64
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00CNEM
- Product description4-((((4-Methoxyphenyl)sulfonyl)oxy)imino)-2,6-dimethylcyclohexa-2,5-dien-1-one
- Packaging2mg
- Price$48
- Updated2026-05-28
- Buy
- ManufacturerAK Scientific
- Product numberSYN5191
- Product descriptionL002
- Packaging50mg
- Price$410
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7739
- Product descriptionL002
- Packaging25mg
- Price$316
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7739
- Product descriptionL002
- Packaging25mg
- Price$332
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7739
- Product descriptionL002
- Packaging10mg
- Price$144
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7739
- Product descriptionL002
- Packaging5mg
- Price$95
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7739
- Product descriptionL002
- Packaging50mg
- Price$587
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7739
- Product descriptionL002
- Packaging50mg
- Price$616
- Updated2026-05-06
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2319
- Product descriptionL 002
- Packaging50mg
- Price$308
- Updated2026-05-19
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2319
- Product descriptionL002-NSC764414 99%
- Packaging10mg
- Price$88
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2319
- Product descriptionL 002
- Packaging10mg
- Price$88
- Updated2026-05-19
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00CNEM | 4-((((4-Methoxyphenyl)sulfonyl)oxy)imino)-2,6-dimethylcyclohexa-2,5-dien-1-one | 10mg | $85 | 2026-05-28 | Buy |
| aablocks | AA00CNEM | 4-((((4-Methoxyphenyl)sulfonyl)oxy)imino)-2,6-dimethylcyclohexa-2,5-dien-1-one | 25mg | $164 | 2026-05-28 | Buy |
| aablocks | AA00CNEM | 4-((((4-Methoxyphenyl)sulfonyl)oxy)imino)-2,6-dimethylcyclohexa-2,5-dien-1-one | 50mg | $295 | 2026-05-28 | Buy |
| aablocks | AA00CNEM | 4-((((4-Methoxyphenyl)sulfonyl)oxy)imino)-2,6-dimethylcyclohexa-2,5-dien-1-one | 100mg | $474 | 2026-05-28 | Buy |
| aablocks | AA00CNEM | 4-((((4-Methoxyphenyl)sulfonyl)oxy)imino)-2,6-dimethylcyclohexa-2,5-dien-1-one | 5mg | $64 | 2026-05-28 | Buy |
| aablocks | AA00CNEM | 4-((((4-Methoxyphenyl)sulfonyl)oxy)imino)-2,6-dimethylcyclohexa-2,5-dien-1-one | 2mg | $48 | 2026-05-28 | Buy |
| AK Scientific | SYN5191 | L002 | 50mg | $410 | 2021-12-16 | Buy |
| ApexBio Technology | B7739 | L002 | 25mg | $316 | 2021-12-16 | Buy |
| ApexBio Technology | B7739 | L002 | 25mg | $332 | 2026-05-06 | Buy |
| ApexBio Technology | B7739 | L002 | 10mg | $144 | 2026-05-06 | Buy |
| ApexBio Technology | B7739 | L002 | 5mg | $95 | 2026-05-06 | Buy |
| ApexBio Technology | B7739 | L002 | 50mg | $587 | 2021-12-16 | Buy |
| ApexBio Technology | B7739 | L002 | 50mg | $616 | 2026-05-06 | Buy |
| Axon Medchem | Axon2319 | L 002 | 50mg | $308 | 2026-05-19 | Buy |
| Axon Medchem | Axon2319 | L002-NSC764414 99% | 10mg | $88 | 2021-12-16 | Buy |
| Axon Medchem | Axon2319 | L 002 | 10mg | $88 | 2026-05-19 | Buy |
Properties
Boiling point :459.8±55.0 °C(Predicted)
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
color :white to beige
InChI :1S/C15H15NO5S/c1-10-8-12(9-11(2)15(10)17)16-21-22(18,19)14-6-4-13(20-3)5-7-14/h4-9H,1-3H3
InChIKey :VEWFTYOFWIXCIO-UHFFFAOYSA-N
SMILES :[S](=O)(=O)(ON=C2C=C(C(=O)C(=C2)C)C)c1ccc(cc1)OC
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
color :white to beige
InChI :1S/C15H15NO5S/c1-10-8-12(9-11(2)15(10)17)16-21-22(18,19)14-6-4-13(20-3)5-7-14/h4-9H,1-3H3
InChIKey :VEWFTYOFWIXCIO-UHFFFAOYSA-N
SMILES :[S](=O)(=O)(ON=C2C=C(C(=O)C(=C2)C)C)c1ccc(cc1)OC
Safety Information
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Description
L002 is an inhibitor of p300 histone acetyltransferase (KAT3B; IC50 = 1.98 μM in vitro). It has weaker inhibitory effects against PCAF and GCN5 (IC50s = 35 and 34 μM, respectively) and is specific for p300 over a panel of additional acetyltransferases, deacetylases, and methyltransferases. L002 blocks acetylation of histones and p53 in cells treated with trichostatin A or etoposide, respectively, and reduces STAT3 phosphorylation, which requires p300-mediated acetylation of STAT3. It induces growth arrest and apoptosis in certain cancer cell lines and, when administered intraperitoneally in mice, suppresses the growth of triple-negative breast cancer xenografts.Related product price
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