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ChemicalBook >> CAS DataBase List >> Podophyllotoxin

Podophyllotoxin

Podophyllotoxin price.
  • $9 - $1720
  • Product name: Podophyllotoxin
  • CAS: 518-28-5
  • MF: C22H22O8
  • MW: 414.41
  • EINECS:208-250-4
  • MDL Number:MFCD00075290
  • Synonyms:Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, (5R,5aR,8aR,9R)-;Podophyllotoxin ,98%;(5R)-5,8,8aβ,9-Tetrahydro-9β-hydroxy-5-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aαH)-one;Podophyllotoxin,95%;trimethoxyphenyl)-furo(3',4':6,7)naphtho[2,3-d]-1,3-dioxol-6(5aH)-one;PODOPHYLLIN(RG);5,8,8a,9-tetrahydro-9-hydroxy-5- (3,4,5-trimethoxyphenyl)-furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5ah)-one;(5R,5AR,8AR,9R)-9-HYDROXY-5-(3,4,5-TRIMETHOXY-PHENYL)-5,8,8A,9-TETRAHYDRO-5AH-FURO[3',4':6,7]NAPHTHO[2,3-D][1,3]DIOXOL-6-ONE
Price86 Properties Safety Information Description
86 prices
Selected condition：
Brand
  • aablocks
  • Adipogen Life Sciences
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • JR MediChem
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Oakwood
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 20mg
  • 50mg
  • 10mM(in1mLDMSO)
  • 250mg
  • 10mM*1mLinDMSO(Solution)
  • 1000mg
  • 2.5g
  • 50g
  • 50 mg
  • 25mg
  • 100mg
  • 500mg
  • 1g
  • 5g
  • 10g
  • 100g
  • 100gG
  • 25g
  • 10mM(in 1mL DMSO)
  • Manufactureraablocks
  • Product numberAA003A9R
  • Product descriptionPodophyllotoxin ≥98%
  • Packaging500mg
  • Price$10
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003A9R
  • Product descriptionPodophyllotoxin ≥98%
  • Packaging1g
  • Price$12
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003A9R
  • Product descriptionPodophyllotoxin ≥98%
  • Packaging5g
  • Price$30
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003A9R
  • Product descriptionPodophyllotoxin 98%
  • Packaging25g
  • Price$96
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003A9R
  • Product descriptionPodophyllotoxin 98%
  • Packaging100g
  • Price$318
  • Updated2026-05-28
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0049-M500
  • Product descriptionPodophyllotoxin ≥98%(HPLC)
  • Packaging500mg
  • Price$85
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0049-M100
  • Product descriptionPodophyllotoxin ≥98%(HPLC)
  • Packaging100mg
  • Price$30
  • Updated2026-05-06
  • Buy
  • ManufacturerAHH
  • Product numberAPI-1441
  • Product descriptionPodophyllotoxin 97%
  • Packaging5g
  • Price$800
  • Updated2026-05-26
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ91208
  • Product descriptionPodophyllotoxin 95%
  • Packaging100gG
  • Price$420
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberF719
  • Product descriptionPodophyllotoxin 98%(HPLC)
  • Packaging100gG
  • Price$576
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ91208
  • Product descriptionPodophyllotoxin 95%
  • Packaging1g
  • Price$12
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberF719
  • Product descriptionPodophyllotoxin 98%(HPLC)
  • Packaging1g
  • Price$18
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10533
  • Product descriptionPodophyllotoxin >98%(HPLC),powder
  • Packaging25mg
  • Price$41
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ91208
  • Product descriptionPodophyllotoxin 95%
  • Packaging5g
  • Price$47
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberF719
  • Product descriptionPodophyllotoxin 98%(HPLC)
  • Packaging5g
  • Price$63
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10533
  • Product descriptionPodophyllotoxin >98%(HPLC),powder
  • Packaging100mg
  • Price$99
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA003A9R Podophyllotoxin ≥98% 500mg $10 2026-05-28 Buy
aablocks AA003A9R Podophyllotoxin ≥98% 1g $12 2026-05-28 Buy
aablocks AA003A9R Podophyllotoxin ≥98% 5g $30 2026-05-28 Buy
aablocks AA003A9R Podophyllotoxin 98% 25g $96 2026-05-28 Buy
aablocks AA003A9R Podophyllotoxin 98% 100g $318 2026-05-28 Buy
Adipogen Life Sciences AG-CN2-0049-M500 Podophyllotoxin ≥98%(HPLC) 500mg $85 2026-05-06 Buy
Adipogen Life Sciences AG-CN2-0049-M100 Podophyllotoxin ≥98%(HPLC) 100mg $30 2026-05-06 Buy
AHH API-1441 Podophyllotoxin 97% 5g $800 2026-05-26 Buy
AK Scientific J91208 Podophyllotoxin 95% 100gG $420 2026-06-04 Buy
AK Scientific F719 Podophyllotoxin 98%(HPLC) 100gG $576 2026-06-04 Buy
AK Scientific J91208 Podophyllotoxin 95% 1g $12 2026-06-04 Buy
AK Scientific F719 Podophyllotoxin 98%(HPLC) 1g $18 2026-06-04 Buy
AK Scientific J10533 Podophyllotoxin >98%(HPLC),powder 25mg $41 2026-06-04 Buy
AK Scientific J91208 Podophyllotoxin 95% 5g $47 2026-06-04 Buy
AK Scientific F719 Podophyllotoxin 98%(HPLC) 5g $63 2026-06-04 Buy
AK Scientific J10533 Podophyllotoxin >98%(HPLC),powder 100mg $99 2026-06-04 Buy
Next Last

Properties

Melting point :183-184 °C (lit.)
alpha :-110.7 º (c=1, CHCl3)
Boiling point :453.31°C (rough estimate)
Density :1.2649 (rough estimate)
refractive index :1.4480 (estimate)
storage temp. :2-8°C
solubility :DMSO:15.0(Max Conc. mg/mL);36.2(Max Conc. mM)
pka :13.26±0.40(Predicted)
form :Powder
color :White to off-white
optical activity :[α]/D 131±2°, c = 1 in chloroform
Merck :13,7628
BRN :99163
Stability :Very Hygroscopic
InChIKey :YJGVMLPVUAXIQN-XVVDYKMHSA-N
SMILES :COc1cc(cc(OC)c1OC)[C@H]2C3C(COC3=O)[C@@H](O)c4cc5OCOc5cc24
LogP :2.010
CAS DataBase Reference :518-28-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): Skull and Crossbones (GHS06)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Podophyllotoxin is a non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum species. It binds to topoisomerase II during the late S and early G2 stage, blocking tubulin polymerization and, thus, inhibiting mitosis. In addition to being used as a cathartic, purgative, antiviral agent, vesicant, and antihelminthic, podophyllotoxin is the starting material for the semi-synthesis of the anti-cancer drugs etoposide , teniposide , and etopophos.

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Suppliers and manufacturers

Shaanxi xintianyu Biotechnology Co., Ltd. Nanjing Shangshu Biotechnology Co., Ltd Wuhan Hongfuda New Materials Co., Ltd. Shaanxi Haochen Biotechnology Co., Ltd Sichuan Hongen Plant Technology Co., Ltd. J & K SCIENTIFIC LTD. Meryer (Shanghai) Chemical Technology Co., Ltd. 3B Pharmachem (Wuhan) International Co.,Ltd. future industrial shanghai co., ltd Chembest Research Laboratories Limited