SBI-0206965
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- $73 - $1800
- Product name: SBI-0206965
- CAS: 1884220-36-3
- MF: C21H21BrN4O5
- MW: 489.32
- EINECS:
- MDL Number:MFCD29472244
- Synonyms:SBI-0206965;SBI0206965; SBI-0206965; SBI 0206965.;Benzamide, 2-[[5-bromo-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]oxy]-N-methyl-;SBI-0206965（02）;2-((5-Bromo-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)oxy)-N-methylbenzamide;SBI 0206965;SBI0206965;CS-1581;SBI-0206965,SBI 0206965,inhibit,Inhibitor,Unc-51 like kinase,Apoptosis,Autophagy,ULK
19 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 5MG
- 10mg
- 25mg
- 50mg
- 250mg
- 1g
- 100mg
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product number4497EC
- Product descriptionCID92044402
- Packaging100mg
- Price$1135
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0004751
- Product description2-(5-BROMO-2-(3,4,5-TRIMETHOXYPHENYLAMINO)PYRIMIDIN-4-YLOXY)-N-METHYLBENZAMIDE 95.00%
- Packaging5MG
- Price$495.76
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8715
- Product descriptionSBI-0206965
- Packaging5mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8715
- Product descriptionSBI-0206965
- Packaging10mM(in 1mL DMSO)
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8715
- Product descriptionSBI-0206965
- Packaging25mg
- Price$350
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545942
- Product descriptionSbI-0206965 >98%
- Packaging5mg
- Price$181.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545942
- Product descriptionSbI-0206965 >98%
- Packaging25mg
- Price$489.6
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18477
- Product descriptionSBI-0206965 ≥98%
- Packaging5mg
- Price$73
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18477
- Product descriptionSBI-0206965 ≥98%
- Packaging10mg
- Price$122
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18477
- Product descriptionSBI-0206965 ≥98%
- Packaging25mg
- Price$288
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18477
- Product descriptionSBI-0206965 ≥98%
- Packaging100mg
- Price$931
- Updated2024-03-01
- Buy
- ManufacturerCrysdot
- Product numberCD11177265
- Product descriptionSBI-0206965 97%
- Packaging10mg
- Price$290
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11177265
- Product descriptionSBI-0206965 97%
- Packaging25mg
- Price$511
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11177265
- Product descriptionSBI-0206965 97%
- Packaging50mg
- Price$869
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8316
- Product descriptionSBI-0206965 >98%
- Packaging250mg
- Price$900
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8316
- Product descriptionSBI-0206965 >98%
- Packaging1g
- Price$1800
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 4497EC | CID92044402 | 100mg | $1135 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0004751 | 2-(5-BROMO-2-(3,4,5-TRIMETHOXYPHENYLAMINO)PYRIMIDIN-4-YLOXY)-N-METHYLBENZAMIDE 95.00% | 5MG | $495.76 | 2021-12-16 | Buy |
| ApexBio Technology | A8715 | SBI-0206965 | 5mg | $100 | 2021-12-16 | Buy |
| ApexBio Technology | A8715 | SBI-0206965 | 10mM(in 1mL DMSO) | $110 | 2021-12-16 | Buy |
| ApexBio Technology | A8715 | SBI-0206965 | 25mg | $350 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb545942 | SbI-0206965 >98% | 5mg | $181.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb545942 | SbI-0206965 >98% | 25mg | $489.6 | 2021-12-16 | Buy |
| Cayman Chemical | 18477 | SBI-0206965 ≥98% | 5mg | $73 | 2024-03-01 | Buy |
| Cayman Chemical | 18477 | SBI-0206965 ≥98% | 10mg | $122 | 2024-03-01 | Buy |
| Cayman Chemical | 18477 | SBI-0206965 ≥98% | 25mg | $288 | 2024-03-01 | Buy |
| Cayman Chemical | 18477 | SBI-0206965 ≥98% | 100mg | $931 | 2024-03-01 | Buy |
| Crysdot | CD11177265 | SBI-0206965 97% | 10mg | $290 | 2021-12-16 | Buy |
| Crysdot | CD11177265 | SBI-0206965 97% | 25mg | $511 | 2021-12-16 | Buy |
| Crysdot | CD11177265 | SBI-0206965 97% | 50mg | $869 | 2021-12-16 | Buy |
| DC Chemicals | DC8316 | SBI-0206965 >98% | 250mg | $900 | 2021-12-16 | Buy |
| DC Chemicals | DC8316 | SBI-0206965 >98% | 1g | $1800 | 2021-12-16 | Buy |
Properties
Melting point :170 - 172°C
Density :1.434±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 30 mg/ml)
pka :14.80±0.46(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Density :1.434±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 30 mg/ml)
pka :14.80±0.46(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Description
ULK1 is a serine/threonine kinase that acts upstream of phosphatidylinositol 3-kinase (PI3K) to regulate the formation of autophagophores, the precursors of autophagosomes, in response to nutrient deprivation. It is activated by phosphorylation by AMPK and, in turn, phosphorylates and inhibits AMPK. SBI-0206965 is an inhibitor of ULK1 (IC50 = 108 nM) that is less effective against ULK2 (IC50 = 711 nM). It is selective for ULK1 and ULK2 over a panel of 456 additional kinases, showing activity against a few kinases in vitro but not in cells. SBI-0206965 suppresses autophagy induced by mTOR inhibition via AZD 8055 . It also blocks ULK1-dependent cell survival following nutrient deprivation.More related product prices
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